2024
Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases
Kawano-Dourado L, Kulkarni T, Ryerson C, Rivera-Ortega P, Baldi B, Chaudhuri N, Funke-Chambour M, Hoffmann-Vold A, Johannson K, Khor Y, Montesi S, Piccari L, Prosch H, Molina-Molina M, Torres J, Bauer-Ventura I, Rajan S, Jacob J, Richards D, Spencer L, Wendelberger B, Jensen T, Quintana M, Kreuter M, Gordon A, Martinez F, Kaminski N, Cornelius V, Lewis R, Adams W, Jenkins G, consortium R, Bravery A, Goodwin A, Etges A, Boshoff A, Günther A, Briggs A, Palmer A, Wilson A, Crawshaw A, Hoffmann-Vold A, Bergeron A, Holland A, Gordon A, Prasse A, Tzouvelekis A, Trachalaki A, Wells A, Nair A, Adegunsoye A, Wendelberger B, Hope-Gill B, Kaul B, Gooptu B, Baldi B, Crestani B, Polanczyk C, Vancheri C, Crobal C, Summers C, Grainge C, Ryerson C, von Garnier C, Huntley C, Ravaglia C, Valenzuela C, Hayton C, McCarthy C, Chambers D, Babalis D, Thicket D, Turner D, Talwar D, Anand D, Dhasmana D, Parek D, Griffiths D, Villegas D, Richards D, Santucci E, Bendstrup E, Balestro E, Tsitoura E, Falaschetti E, Gupta E, Farrand E, Khan F, Martinez F, Bonella F, Lombardi F, Hunninghake G, Saini G, Jenkins G, Gudmundsson G, Collard H, Parfrey H, Prosch H, Fainberg H, Adamali H, Stewart I, Forrest I, Glaspole I, Bauer-Ventura I, Noth I, Cox I, Strambu I, Sellares J, Eaden J, Johnston J, Swigris J, Blaikley J, Kim J, Chung J, Lasky J, Jacob J, Lee J, Behr J, Storrer K, Lewandowska K, Johnson K, Antoniou K, Hostettler K, Johannson K, Hurley K, Hett K, Schwarzkopf L, Fabbri L, Price L, Pearmain L, Kawano-Dourado L, Galvin L, Spencer L, Watson L, Crowley L, Richeldi L, Piccari L, Funke-Chambour M, Molina-Molina M, Jones M, Spears M, Toshner M, Wijsenbeek-Lourens M, Brutsche M, Vasakova M, Quintana M, Gibbons M, Henry M, Keane M, Kreuter M, Man M, Sadatsafavi M, Kaminski N, Chaudhuri N, Weatherley N, Hirani N, Mladinescu O, Spagnolo P, Beirne P, Bryce P, George P, Molyneaux P, Rivera-Ortega P, Crisan-Dabija R, Maida R, Borie R, Takei R, Lewis R, Rolo R, Guler S, Paganoni S, Singh S, Freitas S, Piciucchi S, Malik S, Barratt S, Hart S, Dal Corso S, Fletcher S, Stanel S, Bianchi S, Jones S, Nathan S, Rajan S, Birring S, Montesi S, Reoto T, Corte T, Zaman T, Kulkarni T, Gatheral T, Jensen T, McMillan T, Quinn V, Poletti V, Cornelius V, Cottin V, Adams W, Wuyts W, Kondoh Y, Miyazaki Y, Khor Y, Haider Y. Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases. Thorax 2024, 79: 788-795. PMID: 38448221, PMCID: PMC11287572, DOI: 10.1136/thorax-2023-221148.Peer-Reviewed Original ResearchConceptsFibrotic interstitial lung diseaseInterstitial lung diseaseRandomised controlled trial approachTarget populationCare of peopleImprove patient careLung diseaseDisease associated with significant morbiditySafety of interventionsDissemination of resultsTrial deliveryImprove careProgression of fibrosisPatient careResponse adaptive randomisationPrimary outcomeCareSignificant morbidityAdult patientsApproaches to drug developmentClinical trialsDrug development pipelineTrial approachHeterogeneous groupPatients
2020
Summary and Future Applications of Precision Medicine in Pulmonary, Critical Care, and Sleep Medicine
Gomez J, Kaminski N, Himes B. Summary and Future Applications of Precision Medicine in Pulmonary, Critical Care, and Sleep Medicine. Respiratory Medicine 2020, 417-428. DOI: 10.1007/978-3-030-31507-8_28.Peer-Reviewed Original ResearchCritical careSleep medicinePrecision medicine strategiesNovel biomarker candidatesDisease endotypesClinical studiesDisease pathogenesisHealthcare providersNovel interventionsBiomarker candidatesMedicine strategiesPrecision medicineDrug targetsCareMolecular underpinningsWidespread implementationMedicineEndotypesPulmonaryPathogenesisCohortInitial discoveryBiomarkers
2019
High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report
Hersh CP, Adcock IM, Celedón JC, Cho MH, Christiani DC, Himes BE, Kaminski N, Mathias RA, Meyers DA, Quackenbush J, Redline S, Steiling KA, Tabor HK, Tobin MD, Wurfel MM, Yang IV, Koppelman GH. High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2019, 16: 1-16. PMID: 30592451, PMCID: PMC6812157, DOI: 10.1513/annalsats.201810-716ws.Peer-Reviewed Original ResearchConceptsCritical careSleep medicine researchAmerican Thoracic Society meetingOfficial American Thoracic Society Workshop ReportCommon chronic diseasesMedicine researchNonmalignant diseasesLung cancerChronic diseasesPractice guidelinesRespiratory diseaseBest practice guidelinesSleep medicineStudy designDiseaseWorkshop reportCareReporting of resultsRelevant diseasesSingle-day workshopMonogenic diseasesGenetic epidemiologyReportReview articleSociety meetings
2015
Palliative Care and Location of Death in Decedents With Idiopathic Pulmonary Fibrosis
Lindell KO, Liang Z, Hoffman LA, Rosenzweig MQ, Saul MI, Pilewski JM, Gibson KF, Kaminski N. Palliative Care and Location of Death in Decedents With Idiopathic Pulmonary Fibrosis. CHEST Journal 2015, 147: 423-429. PMID: 25187973, PMCID: PMC4314817, DOI: 10.1378/chest.14-1127.Peer-Reviewed Original ResearchConceptsIdiopathic pulmonary fibrosisLocation of deathPalliative care referralPalliative careCare referralPulmonary fibrosisAdequacy of endCommunity hospital wardsLung transplant recipientsTiming of referralMajority of patientsObituary listingsTransplant recipientsMedian survivalSymptom burdenSpecialty centersFirst visitHospital settingCenter visitsHospital wardsClinical practiceReferralPatientsDecedentsCare
2012
Personalized medicine: applying omics to lung fibrosis
Herazo-Maya JD, Kaminski N. Personalized medicine: applying omics to lung fibrosis. Biomarkers In Medicine 2012, 6: 529-540. PMID: 22917154, PMCID: PMC3517740, DOI: 10.2217/bmm.12.38.Peer-Reviewed Original ResearchConceptsIdiopathic pulmonary fibrosisFibrotic lung diseaseLung transplantPulmonary fibrosisLung fibrosisLung diseaseUnknown etiologyChronic diseasesSporadic formsHigh mortalityPatient careTreatment of diseasesDrug studiesCost-effective strategyDiseaseFibrosisDiagnosisPersonalized medicinePatientsTransplantEtiologyTherapyMortalityCarePrevention
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