Regularized Latent Class Model for Joint Analysis of High-Dimensional Longitudinal Biomarkers and a Time-to-Event Outcome
Sun J, Herazo-Maya J, Molyneaux PL, Maher TM, Kaminski N, Zhao H. Regularized Latent Class Model for Joint Analysis of High-Dimensional Longitudinal Biomarkers and a Time-to-Event Outcome. Biometrics 2018, 75: 69-77. PMID: 30178494, DOI: 10.1111/biom.12964.Peer-Reviewed Original ResearchConceptsJoint latent class modelLongitudinal biomarkersExtensive simulation studyLatent class modelLongitudinal submodelJoint modeling methodSurvival submodelLikelihood approachSimulation studyClass modelEvent outcomesLatent classesModeling methodMembership modelRandom effectsModeling approachClassSubmodelsJoint analysisModelBootstrapUnique trajectoriesNovel biological insightsInference
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