2025
Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study
Dhodapkar M, Halperin S, Day W, Saifi C, Rubio D, Koumpouras F, Grauer J, Varthi A. Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study. North American Spine Society Journal (NASSJ) 2025, 100604. DOI: 10.1016/j.xnsj.2025.100604.Peer-Reviewed Original ResearchPosterior lumbar fusionSystemic lupus erythematosusDiscoid lupus erythematosusSingle-level posterior lumbar fusionPostoperative adverse eventsMinor adverse eventsAdverse eventsIncreased oddsLupus erythematosusLumbar fusionDiagnosis of discoid lupus erythematosusCohort of systemic lupus erythematosusLevel posterior lumbar fusionsMultivariate analysisDiagnosis of systemic lupus erythematosusDiscoid lupus erythematosus patientsUrinary tract infectionPerioperative adverse outcomesSurgical site infectionAcute kidney injuryDeep vein thrombosisNational database studyHistory of infectionSampled adult patientsMultivariate logistic regressionDocumented Cannabis Use Is a Risk Factor for Nonunion After Nonoperative Management of Scaphoid Fractures: A Retrospective Review of 159 998 Patients.
Pathak N, Ratnasamy P, Oghenesume O, Luo X, Grauer J, Halim A. Documented Cannabis Use Is a Risk Factor for Nonunion After Nonoperative Management of Scaphoid Fractures: A Retrospective Review of 159 998 Patients. Hand 2025, 15589447251317225. PMID: 39968879, PMCID: PMC11840816, DOI: 10.1177/15589447251317225.Peer-Reviewed Original ResearchDocumented cannabis useCannabis useNonunion surgeryScaphoid fracturesNonunion rateNon-user groupNonoperative managementMultivariate analysisTreated with nonoperative managementIncreased riskScaphoid nonunionNon-usersPotential associationElectronic medical recordsManagement of scaphoid fracturesAcute scaphoid fracturesIndex fractureTobacco useRetrospective reviewTobacco-onlyFracture patientsAdult patientsFracture diagnosisMatched cohortCannabis-onlyPredictors of Delayed Surgery After Distal Radius Fracture: A Large National Database Study.
Ratnasamy P, Allam O, Kammien A, Joo P, Luo X, Grauer J. Predictors of Delayed Surgery After Distal Radius Fracture: A Large National Database Study. Orthopedics 2025, 48: e75-e80. PMID: 39933104, DOI: 10.3928/01477447-20250204-01.Peer-Reviewed Original ResearchConceptsDistal radius fracturesDelayed surgeryRadius fracturesImmediate surgeryClinical factorsDistal radius fracture surgeryTime of surgeryCohort of patientsDemographics of patientsNon-clinical factorsFracture surgeryIndependent predictorsRetrospective studySurgical timeImpact patient outcomesMultivariate analysisSurgerySmoking statusComorbidity burdenPatientsWeek 0 to 2Patient outcomesWeek 3WeeksNon-clinicalDeclining postoperative ninety-day opioid prescriptions from 2010 to 2021 following hip arthroscopy for femoroacetabular impingement syndrome
Day W, Halperin S, Surucu S, Jimenez A, Katsnelson B, Zhu J, Grauer J. Declining postoperative ninety-day opioid prescriptions from 2010 to 2021 following hip arthroscopy for femoroacetabular impingement syndrome. Arthroscopy Sports Medicine And Rehabilitation 2025, 101078. DOI: 10.1016/j.asmr.2025.101078.Peer-Reviewed Original ResearchPostoperative opioid prescriptionsFemoroacetabular impingement syndromeOpioid prescriptionsPostoperative mmeElixhauser Comorbidity IndexHip arthroscopyNinety-dayHistory of chronic painImpingement syndromeAmount of narcoticsNational administrative databaseChronic painAdult patientsPatient sexPostoperative recoveryMultivariate linear regressionComorbidity indexMultivariate analysisComorbidity burdenClinical relevancePatientsExclusion criteriaSurgeryPatient variablesAdministrative databases
2024
Emergency Department Use Within 90 Days After Single-Level Posterior Cervical Foraminotomy.
Jayaram R, Oghenesume O, Day W, Kammien A, Grauer J. Emergency Department Use Within 90 Days After Single-Level Posterior Cervical Foraminotomy. Orthopedics 2024, 48: 51-56. PMID: 39699166, DOI: 10.3928/01477447-20241213-04.Peer-Reviewed Original ResearchConceptsSingle-level posterior cervical foraminotomyPosterior cervical foraminotomyElixhauser Comorbidity IndexCervical foraminotomyEmergency departmentPredictive factorsMultivariate analysisED visitsAcute postoperative periodPrimary ED diagnosisPatient agePostoperative periodPatient characteristicsSurgical siteFemale sexComorbidity indexIndications of traumaED diagnosisED useRisk factorsYounger agePatientsMultilevel proceduresForaminotomySurgeryPatients on Antidepressants Are at an Increased Risk of Adverse Events following Total Knee Arthroplasty.
Ratnasamy P, Diatta F, Oghenesume O, Sanchez J, Gouzoulis M, Grauer J. Patients on Antidepressants Are at an Increased Risk of Adverse Events following Total Knee Arthroplasty. Journal Of The American Academy Of Orthopaedic Surgeons 2024 PMID: 39637418, DOI: 10.5435/jaaos-d-24-00743.Peer-Reviewed Original ResearchTime of surgeryTotal knee arthroplasty patientsAdverse eventsRevision surgeryTotal knee arthroplastyPatient ageIncreased risk of adverse eventsRisk of adverse eventsElixhauser Comorbidity Index scorePostoperative adverse eventsInferior perioperative outcomesComorbidity Index scoreKnee arthroplastyPerioperative outcomesElixhauser Comorbidity IndexPostoperative outcomesAntidepressant medicationAntidepressantsComorbidity indexMultivariate analysisPatient populationSurgeryIncreased riskLevel IIIPatientsPatients With Diabetes on Sodium-Glucose Cotransporter-2 Inhibitors Undergoing Total Knee Arthroplasty Are at Increased Odds for a Number of Postoperative Adverse Events But Reduced Risk of Transfusion.
Kim L, Wiznia D, Grauer J. Patients With Diabetes on Sodium-Glucose Cotransporter-2 Inhibitors Undergoing Total Knee Arthroplasty Are at Increased Odds for a Number of Postoperative Adverse Events But Reduced Risk of Transfusion. Journal Of The American Academy Of Orthopaedic Surgeons 2024 PMID: 39630933, DOI: 10.5435/jaaos-d-24-00299.Peer-Reviewed Original ResearchSodium-glucose cotransporter 2 inhibitorsDM patientsAdverse eventsDiabetes mellitusTotal knee arthroplastySGLT2i useElixhauser Comorbidity IndexComorbidity indexMultivariate analysisIncidence of blood transfusionReduced risk of transfusionAssociated with multiple complicationsOdds of transfusionUrinary tract infectionAssociated with increased riskPerioperative adverse outcomesRisk of transfusionAssociated with reduced incidenceAcute kidney injuryPostoperative adverse eventsSurgical decision makingControlled DM patientsActive tobacco useGroup of medicationsAssociated with higher oddsEmergency Department Visits Following Supracondylar Humerus Fractures
Gouzoulis M, Yang A, Joo P, Kaszuba S, Frumberg D, Grauer J. Emergency Department Visits Following Supracondylar Humerus Fractures. Journal Of Pediatric Orthopaedics 2024, 45: 128-133. PMID: 39808740, DOI: 10.1097/bpo.0000000000002866.Peer-Reviewed Original ResearchPediatric supracondylar humerus fracturesSupracondylar humerus fracturesHumerus fracturesEmergency departmentSurgical interventionManagement of pediatric supracondylar humerus fracturesHistory of ED visitsOdds ratioED visitsMultivariate logistic regressionPediatric patientsInitial managementPediatric fracturesPredictive factorsEmergency department visitsMultivariate analysisQuality improvement measuresRisk factorsPatientsTime of visitClinical interestMedicaid insuranceAdministrative databasesLogistic regressionDepartment visitsImpact of Surgeon Volume on Perioperative Complications and Survival to Total Hip Arthroplasty Following Femoral Head Core Decompression
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Seddio A, Li M, Wiznia D, Grauer J. Impact of Surgeon Volume on Perioperative Complications and Survival to Total Hip Arthroplasty Following Femoral Head Core Decompression. JAAOS Global Research And Reviews 2024, 8: e24.00153. PMCID: PMC11578193, DOI: 10.5435/jaaosglobal-d-24-00153.Peer-Reviewed Original ResearchFemoral head osteonecrosisHip fractureInvasive proceduresCore decompressionHigh-volume surgeon groupImpact of surgeon volumeTotal hip arthroplastyKaplan-Meier survival analysisHigh-volume surgeonsMinimally invasive procedureSurgeon volume categoriesStatistically significant differenceAssess complicationsPerioperative complicationsPostoperative complicationsElixhauser Comorbidity IndexAdult patientsVolume surgeonsTreatment optionsAdverse eventsSurgeon volumeSurgeon groupComorbidity indexMultivariate analysisComplicationsContinuous Adductor Canal Block Compared to Epidural Anesthesia for Total Knee Arthroplasty
Freedman I, Mercier M, Galivanche A, Sandhu M, Hocevar M, Moore H, Grauer J, Rubin L, Li J. Continuous Adductor Canal Block Compared to Epidural Anesthesia for Total Knee Arthroplasty. Journal Of Pain Research 2024, 17: 3729-3740. PMID: 39559456, PMCID: PMC11572497, DOI: 10.2147/jpr.s462079.Peer-Reviewed Original ResearchContinuous adductor canal blockAdductor canal blockEpidural analgesiaEA patientsNon-home dischargeCanal blockMultivariate analysisIncidence of postoperative adverse eventsPostoperative adverse eventsMorphine equivalentsEpidural anesthesiaAdverse eventsRetrospective analysisHospital lengthProlonged LOSLevel IIIPatientsSteroidsTotal knee arthroplastyAdjuvantTKA patientsLogistic regressionDischarge dispositionAnalgesiaKnee arthroplastyImproved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization
Seddio A, Wilhelm C, Gouzoulis M, Islam W, Vasudevan R, Halperin S, Rubin L, Medvecky M, Donohue K, Grauer J. Improved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization. JSES International 2024 DOI: 10.1016/j.jseint.2024.10.006.Peer-Reviewed Original ResearchTotal shoulder arthroplastyBody mass indexT2DM patientsElixhauser Comorbidity IndexMultivariate analysisOdds of surgical site infectionUrinary tract infectionSurgical site infectionAcute kidney injuryType II diabetes mellitusII diabetes mellitusTract infectionsSite infectionClinical benefitPreoperative optimizationCardiac eventsKidney injuryVenous thromboembolismMetformin useAdverse eventsManagement of type II diabetes mellitusMass indexDiabetes mellitusType II diabetesAdverse outcomesFollowing carpel tunnel release, what factors affect whether patients return to the same or different hand surgeon for a subsequent procedure?
Halperin S, Dhodapkar M, Pathak N, Joo P, Luo X, Grauer J. Following carpel tunnel release, what factors affect whether patients return to the same or different hand surgeon for a subsequent procedure? PLOS ONE 2024, 19: e0312159. PMID: 39436931, PMCID: PMC11495619, DOI: 10.1371/journal.pone.0312159.Peer-Reviewed Original ResearchImpact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty
Smith-Voudouris J, Dhodapkar M, Halperin S, Cohen J, Grauer J. Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e23.00267. PMID: 39436712, PMCID: PMC11498930, DOI: 10.5435/jaaosglobal-d-23-00267.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAdverse eventsOdds of pneumoniaTotal knee arthroplastyPerioperative outcomes of patientsModerate-to-severe diseaseIncreased oddsEmergency departmentUrinary tract infectionChronic inflammatory skin conditionOutcomes of patientsLog-rank testRisk of adverse eventsInflammatory skin conditionIncreased odds of pneumoniaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesImmunosuppressive medicationsTract infectionsAggregate adverse eventsAdult patientsImpact of atopic dermatitisPatient characteristicsMultivariate analysisAfter Primary Total Shoulder Arthroplasty, Factors Associated with Returning to the Same Surgeon for Subsequent Total Shoulder Arthroplasty
Gouzoulis M, Halperin S, Seddio A, Wilhelm C, Moran J, Donohue K, Jimenez A, Grauer J. After Primary Total Shoulder Arthroplasty, Factors Associated with Returning to the Same Surgeon for Subsequent Total Shoulder Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e24.00117. PMID: 39401371, PMCID: PMC11473060, DOI: 10.5435/jaaosglobal-d-24-00117.Peer-Reviewed Original ResearchConceptsTotal shoulder arthroplastyShoulder arthroplastyAdverse eventsPrimary total shoulder arthroplastyTotal shoulder arthroplasty patientsAnatomic total shoulder arthroplastyPatient satisfactionDepression diagnosisMinority of patientsPostoperative adverse eventsAssociated with decreased oddsRevision TSAFactors associated with returnSame surgeonContralateral surgeryElixhauser Comorbidity IndexIpsilateral shoulderFemale sexComorbidity indexMultivariate analysisRevision surgeryComorbidity burdenPatientsImprove patient satisfactionSurgeonsRisk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients
Ratnasamy P, Diatta F, Allam O, Kauke-Navarro M, Grauer J. Risk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients. JAAOS Global Research And Reviews 2024, 8: e24.00040. PMID: 39392934, PMCID: PMC11469891, DOI: 10.5435/jaaosglobal-d-24-00040.Peer-Reviewed Original ResearchConceptsBehcet's syndromeAdverse eventsTotal knee arthroplastyMultivariate analysisRevision surgeryRisk of postoperative complicationsRisk of perioperative adverse eventsTotal hip arthroplastyLog-rank testElixhauser Comorbidity Index scoreRetrospective cohort studyMultisystem autoimmune disorderPostoperative adverse eventsPerioperative adverse eventsComorbidity Index scoreNational administrative databaseKnee arthroplastyTotal knee arthroplasty patientsPostoperative complicationsNo significant differencePatient ageAutoimmune disordersPerioperative managementSyndrome patientsCohort studyRate and Timing of Revision and Contralateral Anterior Cruciate Ligament Reconstruction Relative to Index Surgery
Halperin S, Dhodapkar M, McLaughlin W, Hewett T, Grauer J, Medvecky M. Rate and Timing of Revision and Contralateral Anterior Cruciate Ligament Reconstruction Relative to Index Surgery. Orthopaedic Journal Of Sports Medicine 2024, 12: 23259671241274671. PMID: 39376746, PMCID: PMC11457252, DOI: 10.1177/23259671241274671.Peer-Reviewed Original ResearchAnterior cruciate ligament (ACL) reconstructionContralateral reconstructionRevision ACLRContralateral ACL injuryACL injuryMultivariate logistic regressionLevel of evidenceIpsilateral revisionsCross-sectional studyPatient cohortIpsilateral reconstructionFemale sexMultivariate analysisPatient counselingInjury-prevention programsPatientsTime of revisionYounger ageGraft reinjuryAdministrative databasesLogistic regressionStudy periodACLInjuryPearlDiver90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. 90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study. JAAOS Global Research And Reviews 2024, 8: e24.00069. PMID: 39330875, PMCID: PMC11412709, DOI: 10.5435/jaaosglobal-d-24-00069.Peer-Reviewed Original ResearchConceptsHip fracture surgeryHip fractureGeriatric patientsFracture surgeryAdverse eventsRate of minor adverse eventsCOVID-19 diagnosisWeeks of surgeryMinor adverse eventsTime pointsAssociated with increased oddsComplication rateAssess complicationsCOVID-19 positivityCOVID-19 infectionMultivariate analysisSurgeryComplicationsPatientsDatabase studyReadmission ratesCare algorithmWeeksDiagnosisCOVID-19P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient ageTrends in management of odontoid fractures 2010–2021
Gouzoulis M, Seddio A, Rancu A, Jabbouri S, Moran J, Varthi A, Rubio D, Grauer J. Trends in management of odontoid fractures 2010–2021. North American Spine Society Journal (NASSJ) 2024, 20: 100553. PMID: 39381260, PMCID: PMC11459689, DOI: 10.1016/j.xnsj.2024.100553.Peer-Reviewed Original ResearchOdontoid fracturesSurgical interventionPredictive factorsAdult patientsManagement of odontoid fracturesPosterior stabilizationMethods Adult patientsNon-clinical factorsRate of surgerySampled adult patientsYearly rateAnterior surgeryPosterior surgeryNonoperative careSurgical managementNonsurgical treatmentClinical factorsMale sexPosterior approachMultivariate analysisMedicare insuranceFracture managementSurgeryPatientsMidwest United States
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