Cefazolin Alone Versus Cefazolin With Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Total Joint Arthroplasty
Dhodapkar M, Halperin S, Radford Z, Rubin L, Grauer J, Li M. Cefazolin Alone Versus Cefazolin With Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Total Joint Arthroplasty. Arthroplasty Today 2025, 31: 101613. PMID: 39911247, PMCID: PMC11794179, DOI: 10.1016/j.artd.2024.101613.Peer-Reviewed Original ResearchFive-year implant survivalTotal knee arthroplastyElixhauser Comorbidity IndexProphylactic cefazolinImplant survivalAdverse outcomesComorbidity indexTotal hip arthroplastyAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisStandard prophylactic antibioticsKaplan-Meier analysisLog-rank testPerioperative adverse outcomesPostoperative adverse outcomesProsthetic joint infectionMultivariate logistic regressionAntibiotic prophylaxisProphylaxis regimensTotal knee arthroplasty patientsProphylactic antibioticsSSI ratesComplication of total knee arthroplastyJoint infectionCefazolin
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