2024
Drinking severity mediates the relationship between hypothalamic connectivity and rule-breaking/intrusive behavior differently in young women and men: an exploratory study
Li G, Dong Y, Chen Y, Li B, Chaudhary S, Bi J, Sun H, Yang C, Liu Y, Li C. Drinking severity mediates the relationship between hypothalamic connectivity and rule-breaking/intrusive behavior differently in young women and men: an exploratory study. Quantitative Imaging In Medicine And Surgery 2024, 14: 6669683-6666683. PMID: 39281112, PMCID: PMC11400642, DOI: 10.21037/qims-24-815.Peer-Reviewed Original ResearchLeft temporo-parietal junctionHypothalamic connectionsIntrusion scoresParacentral lobuleAlcohol misuseAdult Self-Report ScaleSeverity of alcohol useSeverity of alcohol misuseTemporo-parietal junctionWhole-brain regressionSeverity of drinkingSelf-report scalesHypothalamic functional connectivityImpact of problem drinkingMotivational circuitsDrinking severityHuman Connectome ProjectMotivated behaviorDrinking measuresFunctional connectivityMediation analysisProblem drinkingRule-breakingAlcohol useNeural circuitsThe inter-related effects of alcohol use severity and sleep deficiency on semantic processing in young adults
Li G, Zhong D, Zhang N, Dong J, Yan Y, Xu Q, Xu S, Yang L, Hao D, Li C. The inter-related effects of alcohol use severity and sleep deficiency on semantic processing in young adults. Neuroscience 2024, 555: 116-124. PMID: 39059740, DOI: 10.1016/j.neuroscience.2024.07.025.Peer-Reviewed Original ResearchMiddle frontal gyrusSemantic processingPittsburgh Sleep Quality IndexPrecentral gyrusPittsburgh Sleep Quality Index scoreAlcohol misuseNeural correlates of semantic processingMiddle frontal gyrus activationRight middle frontal gyrusSeverity of alcohol useAlcohol use severityAssociated with deficitsPrecentral gyrus activationLeft precentral gyrusInfluence of sleep qualityYoung adultsWord comprehensionHuman Connectome Project dataFrontal gyrusNeural correlatesConsumption severityLanguage tasksSleep deficiencyNeural mechanismsMediation analysisSex differences in dorsolateral prefrontal cortical and superior colliculus activities support the impact of alcohol use severity and sleep deficiency on two-back memory
Li G, Cao Y, Yang C, Li X, Yang Y, Yang L, Hao D, Li C. Sex differences in dorsolateral prefrontal cortical and superior colliculus activities support the impact of alcohol use severity and sleep deficiency on two-back memory. Quantitative Imaging In Medicine And Surgery 2024, 14: 4972986-4974986. PMID: 39022273, PMCID: PMC11250293, DOI: 10.21037/qims-24-156.Peer-Reviewed Original ResearchAlcohol use severityWorking memoryPittsburgh Sleep Quality IndexAlcohol misuseSex differencesHuman Connectome ProjectPath modelAssociated with working memory deficitsNeural correlates of working memoryPittsburgh Sleep Quality Index scoreCorrelates of working memoryPrefrontal cortex responsesImpact working memoryWhole-brain regressionComorbid alcohol misusePotential sex differencesManipulation of informationImpact of drinkingDLPFC activationDrinking severityPublished routinesNeural correlatesMemory deficitsNeural measuresSleep deficiencyFunctional Networks of Reward and Punishment Processing and Their Molecular Profiles Predicting the Severity of Young Adult Drinking
Li Y, Yang L, Hao D, Chen Y, Ye-Lin Y, Li C, Li G. Functional Networks of Reward and Punishment Processing and Their Molecular Profiles Predicting the Severity of Young Adult Drinking. Brain Sciences 2024, 14: 610. PMID: 38928610, PMCID: PMC11201596, DOI: 10.3390/brainsci14060610.Peer-Reviewed Original ResearchConnectome-based predictive modelingAlcohol use severityReward processingPunishment processingFunctional connectivityAssociated with alcohol use severityAlcohol misusePatterns of network connectivitySemi-Structured AssessmentYoung adult drinkersYoung adultsGenetics of AlcoholismYoung adult drinkingHuman Connectome Project dataNetwork connectivity featuresFronto-parietalAdult drinkersJuSpace toolboxAdult drinkingNeural fingerprintsMolecular profilingGABAA signalingRewardFunctional networksConnectivity features
2023
Brain Networks and Adolescent Alcohol Use
Yip S, Lichenstein S, Liang Q, Chaarani B, Dager A, Pearlson G, Banaschewski T, Bokde A, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Brühl R, Martinot J, Martinot M, Artiges E, Nees F, Orfanos D, Paus T, Poustka L, Hohmann S, Millenet S, Fröhner J, Smolka M, Vaidya N, Walter H, Whelan R, Schumann G, Garavan H. Brain Networks and Adolescent Alcohol Use. JAMA Psychiatry 2023, 80: 1131-1141. PMID: 37647053, PMCID: PMC10469292, DOI: 10.1001/jamapsychiatry.2023.2949.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestAlcohol use riskAlcohol misuseUse riskAlcohol use disorderMale adolescentsDisorders Identification TestSingle-site studyIntervention effortsWhole-brain patternsMean ageAlcohol use dataLeading causeMagnetic resonance imaging dataMAIN OUTCOMEReward-related processesHigh riskSeparate cohortUse disordersAlcohol consumptionCurrent severityAdolescent neurodevelopmentAlcohol use behaviorsAlcohol useAUDIT scoresThe effects of age on the severity of problem drinking: Mediating effects of positive alcohol expectancy and neural correlates
Chaudhary S, Chen Y, Zhornitsky S, Le T, Zhang S, Chao H, Dominguez J, Li C. The effects of age on the severity of problem drinking: Mediating effects of positive alcohol expectancy and neural correlates. Addiction Biology 2023, 28: e13278. PMID: 37252876, DOI: 10.1111/adb.13278.Peer-Reviewed Original ResearchConceptsPositive alcohol expectanciesAlcohol Use Disorders Identification TestAlcohol expectanciesAlcohol use disorderNeural correlatesCue responsesPath analysisProblem drinkingAlcohol misuseEffect of ageAUDIT scoresRostral anterior cingulate cortexWhole-brain regressionAlcohol cue exposureMiddle occipital cortexModerate alcohol use disorderAlcohol Expectancy QuestionnaireAnterior cingulate cortexAlcohol use severityBilateral rostral anterior cingulate cortexPsychological mechanismsBilateral parahippocampal gyrusCue exposureNeural processesSeverity of problemsProspective associations of psychedelic treatment for co-occurring alcohol misuse and posttraumatic stress symptoms among United States Special Operations Forces Veterans
Armstrong S, Xin Y, Sepeda N, Polanco M, Averill L, Davis A. Prospective associations of psychedelic treatment for co-occurring alcohol misuse and posttraumatic stress symptoms among United States Special Operations Forces Veterans. Military Psychology 2023, 36: 184-191. PMID: 38377244, PMCID: PMC10880491, DOI: 10.1080/08995605.2022.2156200.Peer-Reviewed Original ResearchPost-traumatic stress disorderRisky alcohol useAlcohol useRisky drinkersProspective associationsCognitive functioning changesAlcohol misuseCo-occurring alcohol misusePosttraumatic stress symptomsFuture clinical trialsPTSD symptomsComplex traumaPsychedelic-assisted therapyStress disorderStress symptomsClinical characteristicsClinical trialsDMT treatmentPsychedelic treatmentTraditional interventionsTreatment programSignificant reductionSymptomsRespondersTreatment
2022
Win and Loss Responses in the Monetary Incentive Delay Task Mediate the Link between Depression and Problem Drinking
Chen Y, Dhingra I, Le T, Zhornitsky S, Zhang S, Li C. Win and Loss Responses in the Monetary Incentive Delay Task Mediate the Link between Depression and Problem Drinking. Brain Sciences 2022, 12: 1689. PMID: 36552149, PMCID: PMC9775947, DOI: 10.3390/brainsci12121689.Peer-Reviewed Original ResearchSuperior temporal gyrusMonetary incentive delay taskAlcohol Use Disorders Identification TestParahippocampal gyrusAlcohol misuseNeural correlatesReward processingWhole-brain regressionAltered reward processingIncentive delay taskDepression InventoryBDI-II scoresRight parahippocampal gyrusAlcohol use disorderDelay taskDisorders Identification TestLoss processingTemporal gyrusFrontoparietal regionsNeural markersBeck Depression InventoryDrinking adultsMediation analysisProblem drinkingSeverity of drinkingPilot examination of stress, heart rate variability, and alcohol craving and use among female veterans
Holzhauer CG, Epstein EE, Bickar L, Ellis RA, Pole N, Sofuoglu M, Smelson DA, Mattocks K. Pilot examination of stress, heart rate variability, and alcohol craving and use among female veterans. Frontiers In Psychiatry 2022, 13: 886801. PMID: 36159929, PMCID: PMC9500469, DOI: 10.3389/fpsyt.2022.886801.Peer-Reviewed Original ResearchHeart rate variabilityAlcohol use disorderAlcohol cravingAlcohol misuseFemale veteransRate variabilityStudy periodSelf-reported alcohol cravingPilot dataAssociation of stressSelf-report questionnairesUse disordersVeteran populationWomen veteransDaily drinksDaily assessmentAlcohol useDaily cravingPilot studyOverall alcoholCravingSuccessive differencesPotential roleWomenPilot examinationA Systematic Review of Risk Factors for Suicide Among Persons Living with HIV (1996–2020)
Smith A, Breazeale S, Goulet JL, Vlahov D, Justice AC, Womack JA. A Systematic Review of Risk Factors for Suicide Among Persons Living with HIV (1996–2020). AIDS And Behavior 2022, 26: 2559-2573. PMID: 35107660, DOI: 10.1007/s10461-022-03591-y.Peer-Reviewed Original ResearchConceptsRisk factorsHIV-specific risk factorsInjection drug useHIV-1 RNACause of morbidityShare risk factorsPrevious suicide attemptsQuantitative study designHIV diagnosisPeer-reviewed journalsHIV infectionEligible studiesInclusion criteriaPsychiatric illnessElevated riskGeneral populationAlcohol misuseElectronic databasesDrug useSystematic reviewSuicide attemptsStudy designInitial searchSearch termsHIVPsychedelic treatment for co-occurring alcohol misuse and post-traumatic stress symptoms among United States Special Operations Forces Veterans
Mangini P, Averill L, Davis A. Psychedelic treatment for co-occurring alcohol misuse and post-traumatic stress symptoms among United States Special Operations Forces Veterans. Journal Of Psychedelic Studies 2022, 5: 149-155. DOI: 10.1556/2054.2021.00176.Peer-Reviewed Original ResearchPost-traumatic stress symptomsAlcohol misusePsychedelic treatmentAlcohol useCo-occurring alcohol misuseStress symptomsAnonymous internet-based surveyNovel treatment developmentRigorous longitudinal studiesUnique treatment needsPharmacologic treatmentPsychological flexibilityPsychedelic-assisted therapyInternet-based surveyTreatment needsAlcohol consumptionSymptomsClinical programsComplex sequelaeTreatment developmentCombat exposureLongitudinal studyTreatmentRetrospective reportsVeteransDepression and alcohol use in American Indian adolescents: The influence of family factors
Schick M, Nalven T, Thomas E, Weiss N, Spillane N. Depression and alcohol use in American Indian adolescents: The influence of family factors. Alcohol Clinical And Experimental Research 2022, 46: 141-151. PMID: 35076972, PMCID: PMC8988920, DOI: 10.1111/acer.14748.Peer-Reviewed Original ResearchConceptsCo-occurrence of depressionDepressive symptomsAlcohol useFamily factorsFamily warmthGreater depressive symptomsStatistically significant positive associationCulturally sensitive preventionNationally representative sampleAI adolescentsInfluence of family factorsSignificant positive associationParental monitoringGreater alcohol useRepresentative sampleSensitive preventionTreatment approachesAlcohol misuseGeneral populationLevels of parental monitoringAmerican Indian adolescentsPositive associationSymptomsDepressionIndian adolescents
2021
Armed conflict, HIV, and syndemic risk markers of mental distress, alcohol misuse, and intimate partner violence among couples in Uganda
Mootz JJ, Basaraba CN, Corbeil T, Johnson K, Kubanga KP, Wainberg ML, Khoshnood K. Armed conflict, HIV, and syndemic risk markers of mental distress, alcohol misuse, and intimate partner violence among couples in Uganda. Journal Of Traumatic Stress 2021, 34: 1016-1026. PMID: 34647647, PMCID: PMC8530966, DOI: 10.1002/jts.22740.Peer-Reviewed Original ResearchConceptsSyndemic problemsHIV statusRisk markersIntimate partner violenceSyndemic scoreAlcohol misuseMale partnersMental distressUnknown HIV statusPopulation-based studyRisk of maleHIV/AIDSFemale intimate partner violencePartner violencePsychosocial interventionsHIVSignificant total effectWomenProblem scoresHigh rateNortheastern UgandaMen's exposureExposureConflict exposureTotal effectAlcohol use severity and the neural correlates of the effects of sleep disturbance on sustained visual attention
Li G, Chen Y, Tang X, Li CR. Alcohol use severity and the neural correlates of the effects of sleep disturbance on sustained visual attention. Journal Of Psychiatric Research 2021, 142: 302-311. PMID: 34416549, PMCID: PMC8429210, DOI: 10.1016/j.jpsychires.2021.08.018.Peer-Reviewed Original ResearchConceptsPittsburgh Sleep Quality IndexNeural correlatesAlcohol useSleep disturbancesReaction timeSustained visual attentionAlcohol misuseWhole-brain regressionGreater sleep disturbanceHuman Connectome ProjectSevere alcohol useVisual attentionSustained attentionNeural processesCognitive performanceLow accuracy rateLonger reaction timesPerformance accuracyConnectome ProjectEvaluation and Management of Alcohol use Disorder among Older Adults
Joshi P, Duong KT, Trevisan LA, Wilkins KM. Evaluation and Management of Alcohol use Disorder among Older Adults. Current Geriatrics Reports 2021, 10: 82-90. PMID: 34336549, PMCID: PMC8308079, DOI: 10.1007/s13670-021-00359-5.Peer-Reviewed Original ResearchAlcohol use disorderOlder adultsUse disordersTreatment of AUDPatient screening resultsScreening resultsStandardized screening toolsMost older adultsReviewThe prevalenceSUD treatmentPsychosocial treatmentsAlcohol misuseSubstance misuseBrief interventionScreening toolSubstance useMutual help groupsAdultsCOVID-19 pandemicTreatmentPhysical distancingDisordersLaboratory testsScreeningIncreased isolationPrenatal Stress Exposure and Post-traumatic Stress Disorder Associated With Risk of Postpartum Alcohol Misuse Among Women Veterans
Holzhauer CG, Kroll-Desrosiers A, Kinney RL, Copeland LA, Bastian LA, Mattocks KM. Prenatal Stress Exposure and Post-traumatic Stress Disorder Associated With Risk of Postpartum Alcohol Misuse Among Women Veterans. Women's Health Issues 2021, 31: 596-602. PMID: 34148828, PMCID: PMC10500562, DOI: 10.1016/j.whi.2021.05.002.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderMaternal post-traumatic stress disorderMaternal alcohol misuseAlcohol misuseWomen veteransStress exposurePostpartum periodMultisite prospective cohort studyPTSD diagnosisStress disorderMore stress exposureHigher AUDIT-C scoresProspective cohort studyAlcohol Use Disorders Identification TestAUDIT-C scoresSuch risk factorsPrenatal stress exposureDisorders Identification TestGreater stress exposureVeterans Affairs (VA) medical recordsPostpartum scoresCohort studyInfant outcomesMedical recordsRisk factorsSuicidal ideation and thoughts of self‐harm during the COVID‐19 pandemic: The role of COVID‐19‐related stress, social isolation, and financial strain
Elbogen EB, Lanier M, Blakey SM, Wagner HR, Tsai J. Suicidal ideation and thoughts of self‐harm during the COVID‐19 pandemic: The role of COVID‐19‐related stress, social isolation, and financial strain. Depression And Anxiety 2021, 38: 739-748. PMID: 33949747, PMCID: PMC8239640, DOI: 10.1002/da.23162.Peer-Reviewed Original ResearchThoughts of suicideMultivariable logistic regression analysisSocial isolationCOVID-19 pandemicCoronavirus disease 2019 (COVID-19) pandemicSevere mental illnessFinancial strainLogistic regression analysisRisk of suicideCurrent depressive symptomsCOVID-19Mental health symptomsPublic health interventionsDisease 2019 pandemicCOVID-19-related stressMental health problemsPandemic-related stressUS adultsDepressive symptomsGreater social supportAlcohol misuseHealth problemsMental illnessHealth interventionsHealth symptomsSex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders
Peltier MR, Verplaetse TL, Mineur YS, Gueorguieva R, Petrakis I, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders. Neuropharmacology 2021, 187: 108499. PMID: 33600842, PMCID: PMC7992136, DOI: 10.1016/j.neuropharm.2021.108499.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStress-related disordersAlcohol useMajor depressive disorderAlcohol-related disordersAlcohol use disorderPosttraumatic stress disorderStress regulation systemComplex comorbiditiesDepressive disorderProblematic alcohol useUse disordersAlcohol misuseTherapeutic potentialTrauma exposureSubstance abuseStress disorderAnxiety disordersDisordersExposure resultsProgestogensNeurosteroidsNegative affectWomenComorbiditiesMale counterpartsSyndemic Profiles and Sexual Minority Men’s HIV-Risk Behavior: A Latent Class Analysis
Scheer J, Clark K, Maiolatesi A, Pachankis J. Syndemic Profiles and Sexual Minority Men’s HIV-Risk Behavior: A Latent Class Analysis. Archives Of Sexual Behavior 2021, 50: 2825-2841. PMID: 33483851, PMCID: PMC8295412, DOI: 10.1007/s10508-020-01850-4.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsSyndemic conditionsSexual minority menLatent class analysisAlcohol misusePolydrug useMinority menHIV acquisitionHIV syndemicClass analysisTransmission riskVulnerable subpopulationsReference groupSocioeconomic distressSyndemic theorySyndemicGroup differencesMenStatus characteristicsSocial status characteristicsLatent classesClass membershipMisuseThe moderating role of emotion dysregulation in the relation between potentially morally injurious experiences and alcohol misuse among military Veterans
Forkus S, Schick M, Goncharenko S, Thomas E, Contractor A, Weiss N. The moderating role of emotion dysregulation in the relation between potentially morally injurious experiences and alcohol misuse among military Veterans. Military Psychology 2021, 33: 41-49. PMID: 38536244, PMCID: PMC10013211, DOI: 10.1080/08995605.2020.1842640.Peer-Reviewed Original ResearchPositive emotion dysregulationEmotion dysregulationUS military veteransMilitary veteransAlcohol misuseSample of US military veteransAlcohol misuse interventionsSimple slope testsCommunity sampleMisuse interventionsPMIEsModerating roleVeteransEmotionsDysregulationAlcoholMisusePervasive problemMoral standardsInjury experiencePotential utilityInjury eventsSlope test
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