2024
Diffusion MRI Allows Capturing the Amyloid-β and τ Proteins Status in Alzheimer’s Disease Continuum
Dolci G, Cruciani F, Brusini L, Pini L, Galazzo I, Calhoun V, Menegaz G. Diffusion MRI Allows Capturing the Amyloid-β and τ Proteins Status in Alzheimer’s Disease Continuum. 2024, 00: 1-5. DOI: 10.1109/isbi56570.2024.10635105.Peer-Reviewed Original Research
2014
Trafficking to the Apical and Basolateral Membranes in Polarized Epithelial Cells
Stoops EH, Caplan MJ. Trafficking to the Apical and Basolateral Membranes in Polarized Epithelial Cells. Journal Of The American Society Of Nephrology 2014, 25: 1375-1386. PMID: 24652803, PMCID: PMC4073435, DOI: 10.1681/asn.2013080883.Peer-Reviewed Original ResearchConceptsTrafficking routesCell type-specific variationsDistinct protein compositionTrans-Golgi networkPolarized epithelial cellsCellular trafficking pathwaysEpithelial cellsBasolateral membraneType-specific variationsBasolateral proteinsTrafficking pathwaysRecycling endosomesRenal epithelial cellsDifferent developmental statesCarrier vesiclesProtein distributionProtein compositionTransport functionProteinK-ATPaseCurrent understandingCellsPathwayRemarkable capacityDevelopmental state
2012
Bimodal Protein Distributions in Heterogeneous Oscillating Systems
Dobrzyński M, Fey D, Nguyen L, Kholodenko B. Bimodal Protein Distributions in Heterogeneous Oscillating Systems. Lecture Notes In Computer Science 2012, 7605: 17-28. DOI: 10.1007/978-3-642-33636-2_3.Peer-Reviewed Original Research
2002
Site‐specific cross‐linking analyses reveal an asymmetric protein distribution for a box C/D snoRNP
Cahill NM, Friend K, Speckmann W, Li Z, Terns RM, Terns MP, Steitz JA. Site‐specific cross‐linking analyses reveal an asymmetric protein distribution for a box C/D snoRNP. The EMBO Journal 2002, 21: 3816-3828. PMID: 12110593, DOI: 10.1093/emboj/cdf376.Peer-Reviewed Original ResearchConceptsBox C/D snoRNPsD snoRNPsC-boxBox C/D classSite-specific cross-linking analysisBox C/D small nucleolar ribonucleoproteinsBox C/DAsymmetric protein distributionSmall nucleolar ribonucleoproteinSmall nucleolar RNAsXenopus oocyte nucleusCross-linking analysisNucleolar RNAsNucleolar ribonucleoproteinD motifBox DMutational analysisOocyte nucleusGuide sequenceWidespread modificationProtein distributionFibrillarinFunctional rescueCore proteinSnoRNPs
1997
Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines
Blum M, Toninelli E, Anderson J, Balda M, Zhou J, O'Donnell L, Pardi R, Bender J. Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines. American Journal Of Physiology 1997, 273: h286-h294. PMID: 9249502, DOI: 10.1152/ajpheart.1997.273.1.h286.Peer-Reviewed Original ResearchMeSH Keywords1-Methyl-3-isobutylxanthineActinsBucladesineCells, CulturedCytokinesCytoskeletonElectrophysiologyEndothelium, VascularHumansInfant, NewbornInterferon-gammaMaleMembrane PotentialsMembrane ProteinsMicrocirculationPhosphoproteinsSkinTight JunctionsTumor Necrosis Factor-alphaUmbilical VeinsZonula Occludens-1 ProteinConceptsTransmonolayer electrical resistanceSpecialized intercellular structuresTight junctionsF-actin cytoskeletonLarge vessel ECActin cytoskeletonEndothelial cell typesMicrovascular endothelial cellsCytoskeletal rearrangementsStriking fragmentationF-actinProtein distributionCytochalasin DCell typesIntercellular structuresBarrier regulationCytoskeletal alterationsConfocal microscopyMVEC monolayersZO-1Macromolecular fluxCentral roleEC permeabilityEndothelial cellsPrimary cultures
1995
Hydrogen peroxide-induced endothelial retraction is accompanied by a loss of the normal spatial organization of endothelial cell adhesion molecules.
Bradley JR, Thiru S, Pober JS. Hydrogen peroxide-induced endothelial retraction is accompanied by a loss of the normal spatial organization of endothelial cell adhesion molecules. American Journal Of Pathology 1995, 147: 627-41. PMID: 7677177, PMCID: PMC1870992.Peer-Reviewed Original ResearchConceptsMembrane protein distributionFocal adhesion plaquesAdjacent cellsNormal spatial organizationNew protein synthesisEndothelial cellsSurface protein expressionBeta 3 integrinActin organizationDendrite-like processesCell peripheryEndothelial retractionCell adhesion moleculeHuman umbilical vein endothelial cellsAdhesion plaquesUmbilical vein endothelial cellsCellular metabolismActin filamentsProtein distributionProtein synthesisVein endothelial cellsNormal endothelial cell functionEndothelial cell functionApical capCell retraction
1975
A neutron scattering study of the distribution of protein and RNA in the 30 S ribosomal subunit of Escherichia coli
Moore P, Engelman D, Schoenborn B. A neutron scattering study of the distribution of protein and RNA in the 30 S ribosomal subunit of Escherichia coli. Journal Of Molecular Biology 1975, 91: 101-120. PMID: 1102695, DOI: 10.1016/0022-2836(75)90374-5.Peer-Reviewed Original Research
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