2025
A preliminary investigation of the interaction between expectation and the reflexive allocation of covert spatial attention
Crotty N, Massa N, Tellez D, White A, Grubb M. A preliminary investigation of the interaction between expectation and the reflexive allocation of covert spatial attention. Scientific Reports 2025, 15: 5778. PMID: 39962116, PMCID: PMC11833114, DOI: 10.1038/s41598-025-89845-w.Peer-Reviewed Original ResearchConceptsExogenous spatial attentionSpeed-accuracy tradeoffSpatial attentionCue presenceExogenous cuesNon-target stimuliCovert spatial attentionBehavioral effectsCueing effectsReflexive shiftsSpeed-accuracyOnline studyVisual peripheryCuesVisual targetImplicit knowledgeStimuliVisual informationTemporal dynamicsParticipantsAttentionExpectationsImplicit
2024
Temporal dynamics in psychological assessments: a novel dataset with scales and response times
Su Z, Liu R, Wei Y, Zhang R, Xu X, Wang Y, Zhu Y, Wang L, Liang L, Wang F, Zhang X. Temporal dynamics in psychological assessments: a novel dataset with scales and response times. Scientific Data 2024, 11: 1046. PMID: 39333112, PMCID: PMC11437125, DOI: 10.1038/s41597-024-03888-8.Peer-Reviewed Original ResearchConceptsPsychological assessmentDiagnosis of mental disordersDomain of psychologyResponse time dataEarly diagnosis of mental disordersPrevalence of mental health issuesMental health issuesGAD-7Mental disordersPsychological screeningScale reliabilityMental healthTemporal dynamicsScreening initiativesHealth issuesPublic healthXinxiang Medical UniversityHealthResponse timeScalePsychologyMedical UniversityEnergy partitioning in the cell cortex
Chen S, Seara D, Michaud A, Kim S, Bement W, Murrell M. Energy partitioning in the cell cortex. Nature Physics 2024, 20: 1824-1832. DOI: 10.1038/s41567-024-02626-6.Peer-Reviewed Original ResearchCell cortexEntropy production rateGAP expressionCortical actin filamentsRho GTPase pathwayGTPase pathwayMyosin IIActin filamentsDiversity patternsEnergy partitioningRhoOnsager reciprocityCell phenotypeProtein expressionThermodynamic equilibriumCellsSpiral travelling waveProduction rateTemporal dynamicsLiving systemsActinEnergyWavePhenotypeActivityDynamic functional connectivity in anorexia nervosa: alterations in states of low connectivity and state transitions
Boehm I, Mennigen E, Geisler D, Poller N, Gramatke K, Calhoun V, Roessner V, King J, Ehrlich S. Dynamic functional connectivity in anorexia nervosa: alterations in states of low connectivity and state transitions. Journal Of Child Psychology And Psychiatry 2024, 65: 1299-1310. PMID: 38480007, DOI: 10.1111/jcpp.13970.Peer-Reviewed Original ResearchConceptsAnorexia nervosaFunctional connectivityResting state functional connectivityResting-state functional MRI dataInternalizing mental disordersAssociated with preoccupationOnset of anorexia nervosaFunctional MRI dataFemale healthy controlsHealthy controlsDynamic functional connectivityDynamics of functional connectivityTemporal dynamics of functional connectivityFunctional connectivity statesMental disordersStatic analytical approachesGroup differencesNervosaFractional timeMRI dataAdolescentsConnectivity statesFemale patientsClinical featuresTemporal dynamicsLongitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease
Zhou X, Shen X, Johnson J, Spakowicz D, Agnello M, Zhou W, Avina M, Honkala A, Chleilat F, Chen S, Cha K, Leopold S, Zhu C, Chen L, Lyu L, Hornburg D, Wu S, Zhang X, Jiang C, Jiang L, Jiang L, Jian R, Brooks A, Wang M, Contrepois K, Gao P, Rose S, Tran T, Nguyen H, Celli A, Hong B, Bautista E, Dorsett Y, Kavathas P, Zhou Y, Sodergren E, Weinstock G, Snyder M. Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease. Cell Host & Microbe 2024, 32: 506-526.e9. PMID: 38479397, PMCID: PMC11022754, DOI: 10.1016/j.chom.2024.02.012.Peer-Reviewed Original ResearchHost healthMicrobiome dynamicsBacterial taxaBody sitesMicrobiome stabilityIndividual taxaHuman microbiomeMicrobial compositionMicrobial dynamicsMulti-omicsNasal microbiomeMicrobiomeDisrupt interactionsMolecular markersBody-sitesTaxaHostMetabolic diseasesOral microbiomeInsulin-resistant individualsIndividual-specificTemporal dynamicsClinical featuresComprehensive viewClinical markersTime Course of Attention to a Talker’s Mouth in Monolingual and Close-Language Bilingual Children
Birulés J, Bosch L, Lewkowicz D, Pons F. Time Course of Attention to a Talker’s Mouth in Monolingual and Close-Language Bilingual Children. Developmental Psychology 2024, 60: 135-143. PMID: 37917490, DOI: 10.1037/dev0001659.Peer-Reviewed Original ResearchChild's native languageNative languageNonnative languageSelective attentionEarly linguistic experienceLinguistic experienceBilingual childrenSpanish monolingualsTalker's eyesMonolingualsLanguageTalker's faceTalker's mouthChildren's deploymentBilingualsTalkersEqual attentionTemporal dynamicsDifferential effectsCatalanAttentionUtterancesChildrenFaceTime course
2023
Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection
Chaguza C, Hahn A, Petrone M, Zhou S, Ferguson D, Breban M, Pham K, Peña-Hernández M, Castaldi C, Hill V, Initiative Y, Billig K, Earnest R, Fauver J, Kalinch C, Kerantzas N, Koch T, De Kumar B, Landry M, Ott I, Peaper D, Tikhonova I, Vogels C, Schulz W, Swanstrom R, Roberts S, Grubaugh N. Accelerated SARS-CoV-2 intrahost evolution leading to distinct genotypes during chronic infection. Cell Reports Medicine 2023, 4: 100943. PMID: 36791724, PMCID: PMC9906997, DOI: 10.1016/j.xcrm.2023.100943.Peer-Reviewed Original ResearchConceptsChronic infectionEvolutionary ratesGenetic diversityIntrahost evolutionDistinct genotypesHigher viral genome copiesVirus evolutionary ratesSARS-CoV-2 evolutionUntreated chronic infectionAdvantageous mutationsNucleotide substitutionsViral genome copiesDivergent variantsInfection hypothesisVariant emergenceViral populationsInfectious virusInfectionHallmark changesGenome copiesDifferent genotypesDiversityGenotypesTemporal dynamicsEvolution
2022
Decoding the temporal dynamics of spoken word and nonword processing from EEG
McMurray B, Sarrett ME, Chiu S, Black AK, Wang A, Canale R, Aslin RN. Decoding the temporal dynamics of spoken word and nonword processing from EEG. NeuroImage 2022, 260: 119457. PMID: 35842096, PMCID: PMC10875705, DOI: 10.1016/j.neuroimage.2022.119457.Peer-Reviewed Original ResearchConceptsMultiple word candidatesNeuroscience of languagePatterns of confusionNonword processingImplicit processesLexical developmentWord recognitionNeural basisSpeech decodingPsycholinguistic findingsWord candidatesNeural dynamicsBehavioral methodsCognitive disordersSimple paradigmEEG systemTemporal dynamicsClinical disordersWordsMachine-learning techniquesEEG signalsLanguageNeuroscienceDisordersRecognitionSpatial Gist Extraction During Human Memory Consolidation
Antony JW, Stiver CA, Graves KN, Osborne J, Turk-Browne NB, Bennion KA. Spatial Gist Extraction During Human Memory Consolidation. Journal Of Experimental Psychology Learning Memory And Cognition 2022, 48: 929-941. PMID: 34323577, DOI: 10.1037/xlm0000894.Peer-Reviewed Original ResearchConceptsGist-like representationsMemory consolidationHuman memory consolidationExplicit memoryObject exemplarsGist extractionDistributional learningHuman learningVivid memoriesExperiment 3Virtual mazeExperiment 1Spatial navigationExperiment 2Explicit testsHidden objectBehavioral experimentsMemoryTemporal dynamicsRepresentation increasesNavigation performanceLearningRepresentationConsolidationHuman subjects
2021
Maternal perinatal anxiety and neural responding to infant affective signals: Insights, challenges, and a road map for neuroimaging research
Yatziv T, Vancor EA, Bunderson M, Rutherford HJV. Maternal perinatal anxiety and neural responding to infant affective signals: Insights, challenges, and a road map for neuroimaging research. Neuroscience & Biobehavioral Reviews 2021, 131: 387-399. PMID: 34563563, PMCID: PMC8642296, DOI: 10.1016/j.neubiorev.2021.09.043.Peer-Reviewed Original ResearchConceptsInfant cuesSensitive responsivenessMothers' sensitive responsivenessFunctional neuroimaging studiesMaternal perinatal anxietyPerinatal maternal anxietyPerinatal anxietyCue valenceNeural correlatesAffective signalsSensitive caregivingNeuroimaging studiesCore facetsAnxiety symptomsLongitudinal investigationNeural circuitryMixed findingsDepression symptomsMaternal anxietyAnxietyCuesFuture researchTemporal dynamicsCaregivingCurrent research
2020
Systems biology approaches to macromolecules: the role of dynamic protein assemblies in information processing
Rukhlenko O, Kholodenko B, Kolch W. Systems biology approaches to macromolecules: the role of dynamic protein assemblies in information processing. Current Opinion In Structural Biology 2020, 67: 61-68. PMID: 33126139, PMCID: PMC8062579, DOI: 10.1016/j.sbi.2020.09.007.Peer-Reviewed Original ResearchConceptsProtein assembliesProtein complex dynamicsDynamic protein assembliesMacromolecular protein assembliesSignal transduction networksSystems biology approachMEK-ERK pathwayProtein complexesTransduction networksCellular processesBiology approachMolecular machinesRAS-RAFOncogenic mutationsStructural studiesDrug resistanceTemporal dynamicsAssemblyRecent progressTumorigenesisMutationsPicture highlightsFine tuningPathwayDynamic processTemporal dynamics of visual representations in the infant brain
Bayet L, Zinszer BD, Reilly E, Cataldo JK, Pruitt Z, Cichy RM, Nelson CA, Aslin RN. Temporal dynamics of visual representations in the infant brain. Developmental Cognitive Neuroscience 2020, 45: 100860. PMID: 32932205, PMCID: PMC7498752, DOI: 10.1016/j.dcn.2020.100860.Peer-Reviewed Original ResearchConceptsInfant brainComplex visual stimuliVisual representationPairwise classification accuracyEEG dataNeural correlatesNeural representationMental representationsVisual domainVisual objectsRepresentational contentStimulus onsetVisual stimuliNeural activationNeural activityComputational neuroscienceDevelopmental reorganizationIndividual infantsTemporal dynamicsAdult controlsRepresentationAdultsClassification accuracyNeuroscienceAge groups
2014
Laminar and Temporal Expression Dynamics of Coding and Noncoding RNAs in the Mouse Neocortex
Fertuzinhos S, Li M, Kawasawa YI, Ivic V, Franjic D, Singh D, Crair M, Šestan N. Laminar and Temporal Expression Dynamics of Coding and Noncoding RNAs in the Mouse Neocortex. Cell Reports 2014, 6: 938-950. PMID: 24561256, PMCID: PMC3999901, DOI: 10.1016/j.celrep.2014.01.036.Peer-Reviewed Original ResearchConceptsTemporal expression dynamicsExpression dynamicsDistinct biological processesGene coexpression networksSpecific spatiotemporal expressionSmall RNAsNoncoding RNAsTranscriptional differencesTranscriptional eventsSplicing patternsCoexpression networkMRNA interactionsPotential miRNATranscriptional overlapDeep sequencingBiological processesSpatiotemporal expressionMouse neocortexCell typesTranscriptsStudies of neurodevelopmentIntegrated viewTemporal dynamicsCharacteristic setTranscriptome
2013
Functional diversity among sensory receptors in a Drosophila olfactory circuit
Mathew D, Martelli C, Kelley-Swift E, Brusalis C, Gershow M, Samuel AD, Emonet T, Carlson JR. Functional diversity among sensory receptors in a Drosophila olfactory circuit. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: e2134-e2143. PMID: 23690583, PMCID: PMC3677458, DOI: 10.1073/pnas.1306976110.Peer-Reviewed Original ResearchConceptsOlfactory receptor neuronsFunctional diversityOdorant receptorsCognate odorantsLarval olfactory systemWeaker behavioral responsesPhysiological responsesDrosophila melanogasterSingle olfactory receptor neuronsStrong behavioral responsesDrosophila olfactory circuitStronger physiological responsesDiverse mechanismsBehavioral responsesOlfactory circuitDiverse temporal dynamicsOdor receptorsReceptor neuronsWeaker physiological responsesOlfactory codingOlfactory systemIntriguing questionDiversityReceptorsTemporal dynamics
2011
Temporal dynamics reveal atypical brain response to social exclusion in autism
McPartland JC, Crowley MJ, Perszyk DR, Naples A, Mukerji CE, Wu J, Molfese P, Bolling DZ, Pelphrey KA, Mayes LC. Temporal dynamics reveal atypical brain response to social exclusion in autism. Developmental Cognitive Neuroscience 2011, 1: 271-279. PMID: 21731598, PMCID: PMC3125043, DOI: 10.1016/j.dcn.2011.02.003.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderEvent-related potentialsSocial information processingAtypical brain responsesLate slow waveSignificant social difficultiesSocial exclusionAttentional resourcesEmotional arousalPeer rejectionTypical peersTemporal processingSocial difficultiesBrain responsesComputerized gameOvert behaviorSpectrum disorderInformation processingSocial contextObjective measuresEarly componentAutismTemporal dynamicsChildrenTreatment approaches
2007
Two Gr Genes Underlie Sugar Reception in Drosophila
Dahanukar A, Lei YT, Kwon JY, Carlson JR. Two Gr Genes Underlie Sugar Reception in Drosophila. Neuron 2007, 56: 503-516. PMID: 17988633, PMCID: PMC2096712, DOI: 10.1016/j.neuron.2007.10.024.Peer-Reviewed Original ResearchConceptsSubset of sugarsReporter gene expressionSugar-sensing neuronsDouble mutantSugar receptionMolecular basisGenetic analysisGene expressionGr5aDrosophilaReceptor geneSitu hybridizationGenesNeuronsGr64aPrimary receptorTaste receptorsDistinct projectionsReceptorsTemporal dynamicsSugarsMutantsBehavioral responsesLabellumReporter
2005
Signaling through Receptors and Scaffolds: Independent Interactions Reduce Combinatorial Complexity
Borisov N, Markevich N, Hoek J, Kholodenko B. Signaling through Receptors and Scaffolds: Independent Interactions Reduce Combinatorial Complexity. Biophysical Journal 2005, 89: 951-966. PMID: 15923229, PMCID: PMC1366644, DOI: 10.1529/biophysj.105.060533.Peer-Reviewed Original ResearchConceptsProtein complexesComplex signaling networksDistinct physiological responsesSignaling networksAdaptor proteinDocking siteMolecular eventsTemporal dynamicsPhysiological responsesDistinct sitesIndependent interactionsBranched networkSeparate domainsMolecular speciesDomain-oriented approachCombinatorial increaseReceptorsIndividual sitesSitesComplexesScaffoldsSpeciesTens of thousandsProteinDifferent sites
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