2025
Medicare Parity and Outpatient Mental Health Service Use and Costs Among Beneficiaries With Depression
Tetlow S, Phillips V, Hockenberry J. Medicare Parity and Outpatient Mental Health Service Use and Costs Among Beneficiaries With Depression. JAMA Network Open 2025, 8: e258491. PMID: 40314953, PMCID: PMC12048850, DOI: 10.1001/jamanetworkopen.2025.8491.Peer-Reviewed Original ResearchConceptsMental health service useOutpatient mental health service useHealth service useOut-of-pocket expenditureMental health servicesOutpatient mental health servicesService useMedicare beneficiariesHealth servicesDepression screeningUS Preventive Services Task Force recommendationsAccessibility of mental health servicesMedical Expenditure Panel Survey Household ComponentInterrupted time series designOutpatient mental healthMental health careCost-sharingMental health conditionsEconomic evaluationProportion of beneficiariesTask Force recommendationsBarriers to treatmentNationally representative sampleTime series designOlder with depressionGender-Affirming Surgery for Transgender and Gender Diverse Medicare Beneficiaries
Balkan E, Babbs G, Meyers D, Kelly P, Yee K, Pletta D, Shireman T, Alpert A, Baker K, Hughto J. Gender-Affirming Surgery for Transgender and Gender Diverse Medicare Beneficiaries. JAMA Network Open 2025, 8: e258072. PMID: 40310645, PMCID: PMC12046427, DOI: 10.1001/jamanetworkopen.2025.8072.Peer-Reviewed Original ResearchConceptsGender-affirming surgeryTransgender individualsRates of chronic conditionsTransgenderBeneficiaries' useProportion of residentsRegional differencesDual statusBeneficiariesChronic conditionsDiverse beneficiariesBeneficiary characteristicsMedicare beneficiariesGenderCross-sectional studyMedicare entitlementGender-affirming surgical proceduresPropensity score matchingNational Medicare dataMedicare programMedicaidProportion of Medicare beneficiariesSouthSurgical proceduresDescriptive analysisScreening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer
Huang S, Westvold S, Soulos P, Fan J, Winer E, Zhan H, Lustberg M, Lewin J, Robinson T, Dinan M. Screening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer. JAMA Network Open 2025, 8: e255322. PMID: 40232715, DOI: 10.1001/jamanetworkopen.2025.5322.Peer-Reviewed Original ResearchConceptsBreast cancer-specific mortalityBreast cancer mortalityBreast cancer diagnosisCancer-specific mortalityCancer mortalityCancer diagnosisScreening mammographyHazard of breast cancer-specific deathFee-for-service Medicare Parts AAssociated with reduced breast cancer mortalityLower breast cancer mortalityHazard of breast cancer-specific mortalityBreast cancerImprove breast cancer outcomesScreen-detected breast cancerCohort studyBreast cancer-specific deathStudy of older womenBreast cancer outcomesFee-for-serviceDetection of breast cancerMedicare Part ALater-stage diseaseCox proportional hazards modelsAssociated with early stagesMediators of Racial Inequities in Non‐Small Cell Lung Cancer Care
Hamid S, Lee D, Herrin J, Yu J, Pollack C, Dean L, Gaddy J, Oladele C, Feder S, Canavan M, Nunez-Smith M, Soulos P, Gross C. Mediators of Racial Inequities in Non‐Small Cell Lung Cancer Care. Cancer Medicine 2025, 14: e70757. PMID: 40052387, DOI: 10.1002/cam4.70757.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancer carePhase of careSocioeconomic statusNon-small cell lung cancerIndividual-level socioeconomic statusNeighborhood-level socioeconomic statusMedicare-Medicaid dual eligibilityWhite patientsHealth care accessLung cancer careNon-Hispanic blacksIndirect effects of mediatorsDiagnosis stageStage-appropriate treatmentTwo-year survivalCancer careCare accessEffects of raceOptimal careDual eligiblesCareStructural racismRacial inequalityBlack patientsInadequate evaluationExamining multimorbidity contributors to dementia over time
Klee M, Markwardt S, Elman M, Han L, Leist A, Allore H, Quiñones A. Examining multimorbidity contributors to dementia over time. Alzheimer's & Dementia 2025, 21: e14589. PMID: 39988573, PMCID: PMC11847647, DOI: 10.1002/alz.14589.Peer-Reviewed Original ResearchConceptsAverage attributable fractionDementia incidenceDementia riskAttributable fractionChronic conditionsAssociated with increased risk of dementiaHealth and Retirement Study participantsMedicare fee-for-service beneficiariesAcute myocardial infarctionFee-for-service beneficiariesRetirement Study participantsRisk of dementiaPatterns of comorbiditiesAssociated with increased riskDementia casesMyocardial infarctionClaims algorithmIncident casesADRDStudy participantsIschemic heart diseaseDementiaConfidence intervalsMultimorbidityHeart diseaseQuality of gastrointestinal surgical oncology care according to insurance status
Butensky S, Kerekes D, Bakkila B, Billingsley K, Ahuja N, Johnson C, Khan S. Quality of gastrointestinal surgical oncology care according to insurance status. Journal Of Gastrointestinal Surgery 2025, 29: 101961. PMID: 39800081, DOI: 10.1016/j.gassur.2025.101961.Peer-Reviewed Original ResearchConceptsMedicare-insured patientsNational Cancer DatabaseAdequate lymphadenectomyNegative marginsCancer DatabaseRetrospective study of adult patientsStudy of adult patientsSurvival analysisInsurance statusReceipt of lymphadenectomyCurative-intent resectionGastrointestinal (GI) cancersIncreased risk of deathMultivariate survival analysisAdequacy of lymphadenectomyCox proportional hazards modelsRisk of deathProportional hazards modelResection marginsSurgical oncology careAdjuvant therapyRetrospective studyAdult patientsBiliary organismsLymphadenectomyAssessing Medicare’s Coverage With Evidence Development Program
Mooghali M, Moneer O, Janda G, Dhruva S, Ross J, Ramachandran R. Assessing Medicare’s Coverage With Evidence Development Program. Health Affairs 2025, 44: 32-39. PMID: 39761464, DOI: 10.1377/hlthaff.2024.00814.Peer-Reviewed Original Research
2024
Medicare Local Coverage Determinations: Evidence Quality Is Stronger For Covered Indications
Moneer O, Mooghali M, Moosa K, Ramachandran R, Ross J, Dhruva S. Medicare Local Coverage Determinations: Evidence Quality Is Stronger For Covered Indications. Health Affairs 2024, 43: 1712-1718. PMID: 39626147, DOI: 10.1377/hlthaff.2024.00182.Peer-Reviewed Original ResearchConceptsCentury Cures ActLocal coverage determinationsCures ActQuality of evidenceHigh-risk devicesCoverage decisionsPatient ageClinical evidenceClinical studiesCoverage determinationMedical literatureTherapeutic drugsSixty-fiveCoverage databaseEvidence strengthEvidence qualityEvidence summaryActMedicare coverage decisionsMedicare beneficiary populationHospital COVID-19 Burden and Adverse Event Rates
Metersky M, Rodrick D, Ho S, Galusha D, Timashenka A, Grace E, Marshall D, Eckenrode S, Krumholz H. Hospital COVID-19 Burden and Adverse Event Rates. JAMA Network Open 2024, 7: e2442936. PMID: 39495512, PMCID: PMC11581512, DOI: 10.1001/jamanetworkopen.2024.42936.Peer-Reviewed Original ResearchConceptsCOVID-19 burdenHospital admissionPatient safetyRelative riskCohort studyStudy of hospital admissionsAcute care hospitalsRisk-adjustment variablesRisk-adjusted ratesMedicare hospital admissionsCOVID-19 pandemicStaffing shortagesHospital characteristicsMain OutcomesHospital resilienceSurge capacityMedicare patientsCare hospitalHighest burdenPrevent declinesPatient admissionsStudy sampleElixhauser comorbiditiesCOVID-19Low burdenMedical Devices Applying for Outpatient Medicare Supplemental Payments
Moneer O, Johnston J, Rathi V, Ross J, Dhruva S. Medical Devices Applying for Outpatient Medicare Supplemental Payments. JAMA Health Forum 2024, 5: e244016. PMID: 39546305, PMCID: PMC11568453, DOI: 10.1001/jamahealthforum.2024.4016.Peer-Reviewed Original ResearchConceptsCenters for Medicare & Medicaid ServicesMedicare beneficiariesUS Centers for Medicare & Medicaid ServicesCross-sectional studyCross-sectional analysisPatient demographic characteristicsClinical decision-makingMedicaid ServicesMain OutcomesHispanic patientsClinical evidence requirementsPremarket clinical studyOutpatient settingOutpatient paymentsTraditional pathwaysMedicareSupplemental paymentsFiscal yearTransitional pass-through paymentsReimbursementDemographic dataEffectiveness end pointPathway applicationClinical studiesAuthorization pathwaysRisk of Atherosclerotic Cardiovascular Disease Hospitalizations after Chronic Obstructive Pulmonary Disease Hospitalization among Older Adults.
Mosher C, Osazuwa-Peters O, Nanna M, MacIntyre N, Que L, Jones W, Palmer S, O'Brien E. Risk of Atherosclerotic Cardiovascular Disease Hospitalizations after Chronic Obstructive Pulmonary Disease Hospitalization among Older Adults. Annals Of The American Thoracic Society 2024, 21: 1516-1523. PMID: 39018486, PMCID: PMC11568506, DOI: 10.1513/annalsats.202401-017oc.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary disease hospitalizationsChronic obstructive pulmonary diseaseAtherosclerotic cardiovascular diseaseASCVD hospitalizationHospital outcomesMedicare beneficiariesCardiovascular diseaseHospitalization severityCardiovascular disease hospitalizationCardiovascular disease eventsRisk of cardiovascular diseaseAssociated with higher riskCox proportional hazards modelsPopulation of chronic obstructive pulmonary diseasePulmonary disease hospitalizationsHazard ratio estimatesRisk of atherosclerotic cardiovascular diseaseProportional hazards modelHospital 1 yearRetrospective cohort studyObstructive pulmonary diseaseOlder adultsClaims dataHospitalization riskHigh-risk subgroupsEstimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer’s and related dementias
Ouyang Y, Li F, Li X, Bynum J, Mor V, Taljaard M. Estimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer’s and related dementias. Trials 2024, 25: 732. PMID: 39478608, PMCID: PMC11523597, DOI: 10.1186/s13063-024-08404-2.Peer-Reviewed Original ResearchConceptsIntra-cluster correlation coefficientIntra-cluster correlation coefficient estimationSample size calculationED visitsMedicare dataMedicare fee-for-service beneficiariesEmergency departmentFee-for-service beneficiariesSize calculationDiagnosis of ADRDNational Medicare dataCluster randomized trialHospital referral regionsHospital service areasHealth care systemBackgroundCluster randomized trialsPopulation-level dataRandomized trialsDesign of cluster randomized trialsEvaluate interventionsReferral regionsCare systemICC estimatesADRDCorrelation coefficientBenzodiazepine Utilization in Ischemic Stroke Survivors: Analyzing Initial Excess Supply and Longitudinal Trends
Torres V, Brooks J, Donahue M, Sun S, Hsu J, Price M, Blacker D, Schwamm L, Newhouse J, Haneuse S, Moura L. Benzodiazepine Utilization in Ischemic Stroke Survivors: Analyzing Initial Excess Supply and Longitudinal Trends. Stroke 2024, 55: 2694-2702. PMID: 39417222, PMCID: PMC11729356, DOI: 10.1161/strokeaha.124.047257.Peer-Reviewed Original ResearchConceptsIschemic stroke dischargesSkilled nursing facilityDays supplyMonths prior enrollmentUS Medicare claimsIschemic stroke survivorsPost-acute ischemic strokeIschemic strokeNursing facilitiesStroke survivorsStroke dischargesMedicare claimsBenzodiazepine initiationTraditional Medicare coverageMedicare coverageMedical insuranceBenzodiazepine prescriptionsExamined demographicsAcute ischemic strokeInitiation rateLongitudinal trendsPrescription patternsPart AHospital insurancePrescriptionThe extent and burden of high multimorbidity on older adults in the US: a descriptive analysis of Medicare beneficiaries
Dorr D, Markwardt S, Bobo M, Allore H, Botoseneanu A, Newsom J, Nagel C, Quiñones A. The extent and burden of high multimorbidity on older adults in the US: a descriptive analysis of Medicare beneficiaries. BMC Geriatrics 2024, 24: 777. PMID: 39304796, PMCID: PMC11414248, DOI: 10.1186/s12877-024-05329-y.Peer-Reviewed Original ResearchConceptsHigh multimorbidityMultimorbidity levelOlder adultsHigher levels of multimorbidityHealth and Retirement Study dataAssociated with sociodemographic characteristicsWell-being of older adultsLevels of multimorbidityProgression of multimorbidityImpact of multimorbidityBurden of multimorbidityHigher healthcare utilizationRetirement Study dataYounger birth cohortsMultimorbidity groupsHealthcare utilizationLower educationNon-HispanicMultimorbiditySociodemographic characteristicsMedicare beneficiariesSocioeconomic statusHealth indicatorsBirth cohortChronic diseasesDisparities in Dual-energy X-ray Absorptiometry Scan Utilization Across Race/Ethnic Groups Before and After Hip Fractures
Rudisill K, Ratnasamy P, Sanchez J, Grauer J. Disparities in Dual-energy X-ray Absorptiometry Scan Utilization Across Race/Ethnic Groups Before and After Hip Fractures. JAAOS Global Research And Reviews 2024, 8: e24.00052. PMID: 39303221, PMCID: PMC11419421, DOI: 10.5435/jaaosglobal-d-24-00052.Peer-Reviewed Original ResearchConceptsHip fracture populationHip fractureDEXA scanRace/ethnic groupsElixhauser Comorbidity IndexLesser oddsPatient ageFracture populationScan utilizationComorbidity indexTime of hip fractureBefore hip fractureStudy revealed disparitiesImprove medication accessDual x-ray absorptiometryHip fracture patientsGeriatric hip fracturesX-ray absorptiometryHip fragility fracturesMedication accessNon-white categorySentinel eventsHealthcare systemFragility fracturesFracture patientsTrends in Open Versus Endoscopic Carpal Tunnel Release From 2010 to 2021
Ratnasamy P, Rudisill K, Joo P, Lattanza L, Grauer J. Trends in Open Versus Endoscopic Carpal Tunnel Release From 2010 to 2021. JAAOS Global Research And Reviews 2024, 8: e24.00077. PMID: 38885416, PMCID: PMC11191037, DOI: 10.5435/jaaosglobal-d-24-00077.Peer-Reviewed Original ResearchSocial Determinants of Health and Delivery of Rehabilitation to Older Adults During ICU Hospitalization
Jain S, Murphy T, Falvey J, Leo-Summers L, O’Leary J, Zang E, Gill T, Krumholz H, Ferrante L. Social Determinants of Health and Delivery of Rehabilitation to Older Adults During ICU Hospitalization. JAMA Network Open 2024, 7: e2410713. PMID: 38728030, PMCID: PMC11087837, DOI: 10.1001/jamanetworkopen.2024.10713.Peer-Reviewed Original ResearchConceptsSocial determinants of healthDeterminants of healthOccupational therapyPhysical therapyOlder adultsRural residentsIntensive care unit hospitalizationRehabilitation deliveryIntensive care unitSocial determinantsSocioeconomic disadvantageNational Health and Aging Trends StudyDelivery of physical therapyIllness hospitalizationFactors associated with lower oddsDelivery of rehabilitationIn-hospital rehabilitationMitigate functional declineMedicaid eligibilityBurden of disabilityHigh school educationDual MedicareTrends StudyMedicare claimsLength of staySurvival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals
Jain S, Gan S, Nguyen O, Sudore R, Steinman M, Covinsky K, Makam A. Survival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals. JAMA Network Open 2024, 7: e2413309. PMID: 38805226, PMCID: PMC11134219, DOI: 10.1001/jamanetworkopen.2024.13309.Peer-Reviewed Original ResearchConceptsHealth and Retirement StudyLong-term acute care hospitalHealth and Retirement Study interviewsActivities of daily livingAcute care hospitalsOlder adultsMiddle-agedCognitive statusLong-term acute care hospital admissionCare hospitalCohort studyAcute illnessAssociated with lower riskIncreased likelihood of deathAdverse outcomesLikelihood of deathMultivariate logistic regressionReceipt of mechanical ventilationSevere impairmentDaily livingRetirement StudyRetrospective cohort studyMedicare claimsLee index scoresMain OutcomesMedicare Coverage and Patient Out-of-Pocket Costs for Cardiovascular-Kidney-Metabolic Medications
Young G, Bansal K, Riello R, Clark K, Dhruva S, Faridi K, Desai N. Medicare Coverage and Patient Out-of-Pocket Costs for Cardiovascular-Kidney-Metabolic Medications. JAMA Network Open 2024, 7: e2412437. PMID: 38771578, PMCID: PMC11109768, DOI: 10.1001/jamanetworkopen.2024.12437.Peer-Reviewed Original ResearchMortality and morbidity ramifications of proposed retractions in healthcare coverage for the United States
Pandey A, Fitzpatrick M, Singer B, Galvani A. Mortality and morbidity ramifications of proposed retractions in healthcare coverage for the United States. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2321494121. PMID: 38648491, PMCID: PMC11066981, DOI: 10.1073/pnas.2321494121.Peer-Reviewed Original Research
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