2025
Finding the optimal length of stay for veterans in substance use disorder residential treatment using generalized propensity score modeling
Dams G, Gross G, Ketchen B, Smith N, Burden J. Finding the optimal length of stay for veterans in substance use disorder residential treatment using generalized propensity score modeling. International Journal Of Drug Policy 2025, 137: 104715. PMID: 40024631, DOI: 10.1016/j.drugpo.2025.104715.Peer-Reviewed Original ResearchConceptsSubstance use disordersResidential treatmentSevere substance use disordersTreatment outcomesComplex clinical needsVeterans AffairsResidential programsLength of stayDepartment of Veterans AffairsOptimal length of stayResidential centersMethodological issuesVeteransEnhanced outcomesClinical assessmentIndividual patient needsGeneralized propensity score modelAssociation of malnutrition with surgical outcomes after spine surgery for spinal epidural abscess
Elsamadicy A, Serrato P, Ghanekar S, Mitre L, Khalid S, Lo S, Sciubba D. Association of malnutrition with surgical outcomes after spine surgery for spinal epidural abscess. Clinical Neurology And Neurosurgery 2025, 249: 108754. PMID: 39862535, DOI: 10.1016/j.clineuro.2025.108754.Peer-Reviewed Original ResearchConceptsSpinal epidural abscessNon-routine dischargeNational Surgical Quality Improvement ProgramLength of stayAdverse eventsMalnourished cohortEpidural abscessAmerican College of SurgeonsSurgical outcomesPredictors of poor surgical outcomeSpinal epidural abscess patientsNutritional statusSurgical Quality Improvement ProgramMultivariate logistic regression analysisPoor surgical outcomesExtended length of stayPost-operative outcomesAssociation of malnutritionRetrospective cohort studyIncreased LOSPost-surgical outcomesLogistic regression analysisQuality Improvement ProgramSEA patientsSpine surgeryImpact of patient age on morbidity and mortality in adults with acute traumatic cervical spinal cord injury: An ACS trauma quality programs database study
Elsamadicy A, Serrato P, Belkasim S, Ghanekar S, Khalid S, Lo S, Sciubba D. Impact of patient age on morbidity and mortality in adults with acute traumatic cervical spinal cord injury: An ACS trauma quality programs database study. Clinical Neurology And Neurosurgery 2025, 249: 108740. PMID: 39813756, DOI: 10.1016/j.clineuro.2025.108740.Peer-Reviewed Original ResearchConceptsIn-hospital mortalityAcute CSCI patientsLength of stayCSCI patientsTreatment modalitiesCervical SCIAcute traumatic cervical spinal cord injuryTraumatic cervical spinal cord injuryAssociated with increased morbidityImpact of patient ageAcute cervical SCICervical spinal cord injuryRetrospective cohort studyMultivariate logistic regressionPredictors of AEYears of ageSpinal cord injuryCervicothoracic fusionAssociated with AECervical fusionPatient ageIndependent predictorsInjury typePatient demographicsProgram database
2024
Association of Safety-Net hospital status and hospital outcomes following ACDF or PCDF for CSM
Elsamadicy A, Sayeed S, Sherman J, Craft S, Reeves B, Hengartner A, Ghanekar S, Sadeghzadeh S, Larry Lo S, Sciubba D. Association of Safety-Net hospital status and hospital outcomes following ACDF or PCDF for CSM. Journal Of Clinical Neuroscience 2024, 133: 111001. PMID: 39742780, DOI: 10.1016/j.jocn.2024.111001.Peer-Reviewed Original ResearchConceptsCervical spondylotic myelopathySafety net hospitalProportion of patientsNon-routine dischargeNon-SNHsAdverse eventsMultivariate analysisPosterior cervical decompressionAnterior cervical discectomyDischarge dispositionNational Inpatient Sample databaseRetrospective cohort studyNon-routine discharge dispositionPredictors of prolonged LOSICD-10-CM codesInpatient Sample databaseICD-10-CMTreating hospital characteristicsACDF cohortElective ACDFCervical decompressionCervical discectomySpondylotic myelopathyStudy patientsIndependent predictorsAnalysis of short- and delayed unplanned readmission rates after anterior discectomy and fusion for CSM
Elsamadicy A, Sayeed S, Sadeghzadeh S, Hengartner A, Ghanekar S, Serrato P, Khalid S, Lo S, Sciubba D. Analysis of short- and delayed unplanned readmission rates after anterior discectomy and fusion for CSM. Journal Of Clinical Neuroscience 2024, 133: 110993. PMID: 39742778, DOI: 10.1016/j.jocn.2024.110993.Peer-Reviewed Original ResearchConceptsCervical spondylotic myelopathyNationwide Readmissions DatabaseTreatment of cervical spondylotic myelopathyCervical spondylotic myelopathy patientsAnterior cervical discectomyDrivers of readmissionModified frailty indexRetrospective cohort studyAcute kidney failureNon-readmitted patientsPatient- and hospital-level factorsPatient demographic informationCervical discectomySpondylotic myelopathyAnterior discectomyAdult patientsAdverse eventsHospital-level factorsCohort studyICD-10 codesReadmissions DatabaseACDFPatientsKidney failureFrailty scoreEffects of Buprenorphine, Methadone, and Substance Use on COVID-19 Morbidity and Mortality
Christian N, Zhou X, Radhakrishnan R. Effects of Buprenorphine, Methadone, and Substance Use on COVID-19 Morbidity and Mortality. Journal Of Addiction Medicine 2024, 19: 223-226. PMID: 39475125, DOI: 10.1097/adm.0000000000001386.Peer-Reviewed Original ResearchConceptsActive substance useSubstance useAssociated with increased morbidityDuration of hospitalizationCOVID-19 outcomesOpioid useSubstance use disordersImpact of substance useCOVID-19 infectionEffects of buprenorphineOpioid use disorderRetrospective cohort studyUse disorderAll-cause mortalityCOVID-19 positive patientsUrine toxicologyMultivariate logistic regressionAssociated with statistically significant increasesMedical comorbidityStatistically significant differenceMOUD treatmentStatistically significant increaseAssociated with worse COVID-19 outcomesCOVID-19 morbidityUrban hospital systemOptimizing hospital length of stay after infrainguinal bypass: Should ultrashort set the bar?
Said S, Ochoa Chaar C. Optimizing hospital length of stay after infrainguinal bypass: Should ultrashort set the bar? Journal Of Vascular Surgery 2024, 80: 1191. PMID: 39306445, DOI: 10.1016/j.jvs.2024.05.006.Peer-Reviewed Original ResearchUse of Early Ketamine Sedation and Association With Clinical and Cost Outcomes Among Mechanically Ventilated Patients With COVID-19: A Retrospective Cohort Study
Royce-Nagel G, Jarzebowski M, Wongsripuemtet P, Krishnamoorthy V, Fuller M, Ohnuma T, Treggiari M, Yaport M, Cobert J, Garrigan E, Bartz R, Raghunathan K. Use of Early Ketamine Sedation and Association With Clinical and Cost Outcomes Among Mechanically Ventilated Patients With COVID-19: A Retrospective Cohort Study. Critical Care Explorations 2024, 6: e1105. PMID: 38904975, PMCID: PMC11196078, DOI: 10.1097/cce.0000000000001105.Peer-Reviewed Original ResearchConceptsRenal replacement therapyLength of stayHospital length of stayHigher hospital mortalityKetamine infusionTotal hospital costsHospital mortalityVasopressor daysKetamine useVentilator daysSample of U.S. hospitalsRenal replacement therapy useAssociated with higher hospital mortalityDays of mechanical ventilationAssociated with in-hospital mortalityHospital costsManagement of critically ill patientsExtracorporeal membrane oxygenationPropensity score matching analysisRetrospective cohort studyPremier Healthcare DatabaseDays of hospitalizationDays of intubationMechanically ventilated patientsCritically ill patientsEarly prediction of long hospital stay for Intensive Care units readmission patients using medication information
Zhang M, Kuo T. Early prediction of long hospital stay for Intensive Care units readmission patients using medication information. Computers In Biology And Medicine 2024, 174: 108451. PMID: 38603899, PMCID: PMC11385457, DOI: 10.1016/j.compbiomed.2024.108451.Peer-Reviewed Original ResearchConceptsIntensive care unitProlonged ICU LOSAverage doseICU LOSLonger hospital stayReceiver operating characteristic curveLogistic regressionPredicting intensive care unitMedical informationExpected Calibration ErrorSummed dosePatient ageHospital staySupport vector machineCare unitMIMIC-IV databasePatient complicationsCharacteristic curveMedicationRandom forestDosePatient recordsAdmissionReadmission patientsUse of The Risk Assessment and Prediction Tool to Predict Same-day Discharge After Primary Hip and Knee Arthroplasty
Dupont M, Held M, Shah R, Cooper H, Neuwirth A, Hickernell T. Use of The Risk Assessment and Prediction Tool to Predict Same-day Discharge After Primary Hip and Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e22.00269. PMID: 38456719, PMCID: PMC10923310, DOI: 10.5435/jaaosglobal-d-22-00269.Peer-Reviewed Original ResearchConceptsSame-day dischargeTotal knee arthroplastyTotal hip arthroplastyTertiary care centerPreoperative screening toolReceiver operating characteristic curveRAPT scoreScreening toolLogistic regression analysisAssociated with same-day dischargeKnee arthroplastyCutoff valuePreoperative notesPredictive valueCare centerPatientsCharacteristic curveSame-dayDischarge dispositionDischarge planningRegression analysisArthroplastyPositive associationScoresCutoff
2023
Impact of frailty on complications and length of stay after minimally invasive adrenalectomy surgery
Ahuja V, Gibson C, Machado N, King J. Impact of frailty on complications and length of stay after minimally invasive adrenalectomy surgery. Surgery 2023, 175: 336-341. PMID: 38049363, DOI: 10.1016/j.surg.2023.10.023.Peer-Reviewed Original ResearchConceptsFrailty indexInvasive adrenalectomySurgical indicationsBenign diseaseMalignant diseaseMost adverse outcomesStay 2 daysImpact of frailtyThirty-day mortalityLength of stayRelationship of ageAdrenalectomy patientsAdrenalectomy proceduresAdrenalectomy surgeryElective adrenalectomyPerioperative outcomesAdrenal surgeryComplication rateOlder patientsAdrenal diseaseMedian lengthSurgical outcomesAdverse outcomesEndocrine disordersEndocrine diseasesOlder adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system
Ufongene C, Van Hyfte G, Agarwal P, Goldstein J, Mathew B, Navis A, McCarthy L, Kwon C, Gururangan K, Balchandani P, Marcuse L, Naasan G, Singh A, Young J, Charney A, Nadkarni G, Jette N, Blank L, Group S. Older adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system. Seizure 2023, 114: 33-39. PMID: 38039805, PMCID: PMC10841585, DOI: 10.1016/j.seizure.2023.11.018.Peer-Reviewed Original ResearchMeSH KeywordsAgedCOVID-19EpilepsyHospital MortalityHospitalizationHospitalsHumansLength of StayRetrospective StudiesSARS-CoV-2ConceptsInternational Classification of DiseasesLength of stayOlder adultsDischarge dispositionHigher in-hospital mortalityHealth systemIn-hospital deathIn-hospital mortalityMulti-hospital health systemOdds of in-hospital deathAssociated with increased oddsAssociated with increased odds of in-hospital deathNew York health systemMultivariate logistic regression modelClassification of DiseasesConsecutive older patientsAssociated with higher in-hospital mortalityLogistic regression modelsCompare in-hospital outcomesFactors associated with mortalityNon-routine discharge dispositionAssociated with higher ratesOlder peopleInternational ClassificationAdmitted with COVID-19Early observations with an ERAS pathway for thyroid and parathyroid surgery: Moving the goalposts forward
Machado N, Mortlock R, Maduka R, Souza Cunha A, Dyer E, Long A, Canner J, Tanella A, Gibson C, Hyman J, Ogilvie J. Early observations with an ERAS pathway for thyroid and parathyroid surgery: Moving the goalposts forward. Surgery 2023, 175: 114-120. PMID: 37973430, PMCID: PMC10838521, DOI: 10.1016/j.surg.2023.06.052.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidHumansLength of StayMorphine DerivativesPain, PostoperativePostoperative ComplicationsThyroid GlandConceptsSurgery pathwayEnhanced recoverySurgery groupParathyroid surgerySignificant decreasePost-anesthesia care unit lengthAverage daily pain scoreSuperficial cervical plexus blockThyroid/parathyroid surgeryAverage daily morphineDaily pain scoresCervical plexus blockCases 1 yearStandard of careDaily morphineERAS pathwayPostoperative admissionPostoperative antiemeticsPostoperative morphineUnanticipated admissionPain scoresPerioperative outcomesPlexus blockProspective trialPatient groupEffect of Complementary Interventions to Redesign Care on Teamwork and Quality for Hospitalized Medical Patients : A Pragmatic Controlled Trial.
O'Leary K, Johnson J, Williams M, Estrella R, Hanrahan K, Leykum L, Smith G, Goldstein J, Kim J, Thompson S, Terwilliger I, Song J, Lee J, Manojlovich M. Effect of Complementary Interventions to Redesign Care on Teamwork and Quality for Hospitalized Medical Patients : A Pragmatic Controlled Trial. Annals Of Internal Medicine 2023, 176: 1456-1464. PMID: 37903367, DOI: 10.7326/m23-0953.Peer-Reviewed Original ResearchMeSH KeywordsHealth PersonnelHumansLength of StayPhysiciansQuality of Health CareSurveys and QuestionnairesConceptsLength of stayAdverse eventsHealth care professionalsPatient outcomesImplementation of interventionsMedical patientsTeamwork climateCare professionalsPatient experienceHospitalized medical patientsHospital care deliveryImproved patient outcomesTeamwork climate scoresHigh-quality careEffects of interventionsPatient engagement activitiesA PragmaticSecondary outcomesHospitalized patientsPrimary outcomeInterprofessional roundsPatientsMedical unitsPhysician teamCare deliveryEffect Modifiers of the Association of High-Flow Nasal Cannula and Bronchiolitis Length of Stay.
Winer J, Richardson T, Berg K, Berry J, Chang P, Etinger V, Hall M, Kim G, Meneses Paz J, Treasure J, Aronson P. Effect Modifiers of the Association of High-Flow Nasal Cannula and Bronchiolitis Length of Stay. Hospital Pediatrics 2023, 13: 1018-1027. PMID: 37795554, PMCID: PMC10593863, DOI: 10.1542/hpeds.2023-007295.Peer-Reviewed Original ResearchMeSH KeywordsBronchiolitisCannulaHumansInfantLength of StayOxygen Inhalation TherapyRetrospective StudiesConceptsEffect of HFNCICU servicesEffect modifiersHigh-flow nasal cannula therapyMulticenter retrospective cohort studyPediatric Health Information SystemAge groupsHigh-flow nasal cannulaNon-ICU patientsRetrospective cohort studyComplex chronic conditionsMultivariable Poisson regressionFuture prospective studiesPotential effect modifiersInitial desaturationInitial tachypneaCohort studyClinical factorsNasal cannulaHospital recordsProspective studyHospitalized childrenChronic conditionsHFNCPatientsRacial disparities in complications following elective colon cancer resection: Impact of laparoscopic versus robotic approaches
Ahuja V, Paredes L, Leeds I, Perkal M, Tsutsumi A, Bhandarkar S, King J. Racial disparities in complications following elective colon cancer resection: Impact of laparoscopic versus robotic approaches. The American Journal Of Surgery 2023, 227: 85-89. PMID: 37806892, PMCID: PMC10842593, DOI: 10.1016/j.amjsurg.2023.09.038.Peer-Reviewed Original ResearchConceptsRC patientsLaparoscopic colectomyElective colon cancer resectionImpact of laparoscopicACS-NSQIP databaseColon cancer resectionMultivariable logistic regressionCancer resectionWhite patientsBlack patientsRobotic colectomyHigher complicationsOperative approachMinority patientsPatientsComplicationsColectomyLogistic regressionRobotic approachRacial disparitiesLaparoscopicCausal pathwaysLower ratesOutcomesMortalityOncology hospitalist impact on hospice utilization
Prsic E, Morris J, Adelson K, Parker N, Gombos E, Kottarathara M, Novosel M, Castillo L, Rothberg BE. Oncology hospitalist impact on hospice utilization. Cancer 2023, 129: 3797-3804. PMID: 37706601, DOI: 10.1002/cncr.35008.Peer-Reviewed Original ResearchMeSH KeywordsDeathHospicesHospitalistsHumansLength of StayMedical OncologyNeoplasmsQuality of LifeRetrospective StudiesConceptsMedical oncology serviceOncology servicesEnd of lifeAdvanced cancerInpatient hospiceHospice utilizationHigher total health care costsTotal health care costsComfort-focused careInpatient oncology serviceSmilow Cancer HospitalAdjusted odds ratioLength of staySolid tumor malignanciesLong-term survivalMultivariable linear regressionHealth care costsElectronic medical recordsHospice transitionUnplanned hospitalizationDischarge dispositionHospice referralInpatient managementLate referralCancer HospitalThe effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service
Ferrara M, Guloksuz S, Hazan H, Li F, Tek C, Sykes L, Riley S, Keshavan M, Srihari V. The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service. Schizophrenia Research 2023, 260: 198-204. PMID: 37688984, DOI: 10.1016/j.schres.2023.08.005.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesLength of stayUntreated psychosisPsychiatric hospitalizationFirst-episode servicesDuration of hospitalizationIncidence rate ratiosNon-affective psychosisNew Haven areaPoisson regression modelsPatient characteristicsHospitalization ratesRecent onsetMedical recordsHospitalizationEffect of durationNegative binomial regressionSpecialized treatmentPsychosisRate ratioBinomial regressionAdmissionDUPEnrollmentFirst yearNational Trends in Microtia Repair Cost and Hospital Length of Stay
Hauc S, Boroumand S, Hosseini H, Ihnat J, Rivera J, Almeida M, Stögner V, Huelsboemer L, Alperovich M. National Trends in Microtia Repair Cost and Hospital Length of Stay. Journal Of Craniofacial Surgery 2023, 34: 2026-2029. PMID: 37582283, DOI: 10.1097/scs.0000000000009599.Peer-Reviewed Original ResearchConceptsPatient ageInclusion criteriaNational Inpatient Sample databaseNinth Revision diagnostic codesPatient-level factorsRevision diagnostic codesRetrospective data analysisQuality of lifeAffected young childrenHospital lengthHospital stayNIS databaseDiagnostic codesConsideration patientsReconstructive proceduresReconstructive surgeryInternational ClassificationPatientsAesthetic outcomeMicrotia correctionPrivate insurancePrivate hospitalsSample databaseMicrotia repairMultifactorial impactIn‐hospital outcomes in patients with and without epilepsy diagnosed with COVID‐19—A cohort study
Ufongene C, Van Hyfte G, Agarwal P, Blank L, Goldstein J, Mathew B, Lin J, Navis A, McCarthy L, Gururangan K, Peschansky V, Kwon C, Cohen A, Chan A, Dhamoon M, Deng P, Gutzwiller E, Hao Q, He C, Nunez W, Klenofsky B, Lemus H, Marcuse L, Roberts M, Schorr E, Singh A, Tantillo G, Young J, Balchandani P, Festa J, Naasan G, Charney A, Nadkarni G, Jetté N. In‐hospital outcomes in patients with and without epilepsy diagnosed with COVID‐19—A cohort study. Epilepsia 2023, 64: 2725-2737. PMID: 37452760, DOI: 10.1111/epi.17715.Peer-Reviewed Original ResearchMeSH KeywordsAgedCohort StudiesCOVID-19EpilepsyHospital MortalityHospitalsHumansLength of StayRetrospective StudiesConceptsLength of stayNon-routine dischargeCharlson Comorbidity IndexIn-hospital outcomesHigher Charlson comorbidity indexFactors associated with higher oddsIntensive care unitInternational Classification of DiseasesOlder ageAssociated with COVID-19 mortalityRegression modelsClassification of DiseasesDecreased LOSLonger length of stayLogistic regression modelsAssociated with mortalityHealth systemOrdinary least squares regression modelsCOVID-19 mortalityOlder adultsRetrospective study of patientsInternational ClassificationHigher oddsMulticenter health systemEvaluate in-hospital outcomes
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