2024
Abbreviated MRI in the evaluation of dizziness: report turnaround times and impact on length of stay compared to CT, CTA, and conventional MRI
Tu L, Tegtmeyer K, de Oliveira Santo I, Venkatesh A, Forman H, Mahajan A, Melnick E. Abbreviated MRI in the evaluation of dizziness: report turnaround times and impact on length of stay compared to CT, CTA, and conventional MRI. Emergency Radiology 2024, 31: 705-711. PMID: 39034381, DOI: 10.1007/s10140-024-02273-7.Peer-Reviewed Original ResearchLength of stayEvaluation of dizzinessAbbreviated MRIConventional MRIMRI protocolEmergency departmentNon-contrast CT headConventional MRI protocolHead and neckPosterior circulation strokeAnalysis of length of stayTurnaround timeED length of stayCT headNo significant differenceAcute dizzinessCirculation strokeRetrospective analysisDizzinessAcute settingAssociated with greater impactMRI studiesImaging modalitiesMRIPatients
2023
CT With CTA Versus MRI in Patients Presenting to the Emergency Department With Dizziness: Analysis Using Propensity Score Matching.
Tu L, Navaratnam D, Melnick E, Forman H, Venkatesh A, Malhotra A, Yaesoubi R, Sureshanand S, Sheth K, Mahajan A. CT With CTA Versus MRI in Patients Presenting to the Emergency Department With Dizziness: Analysis Using Propensity Score Matching. American Journal Of Roentgenology 2023, 221: 836-845. PMID: 37404082, DOI: 10.2214/ajr.23.29617.Peer-Reviewed Original ResearchConceptsSecondary stroke prevention medicationsStroke prevention medicationsEmergency departmentPrevention medicationsEchocardiography evaluationPosterior circulation strokeProportion of patientsGroup of patientsPhysical examination findingsNeuroimaging resultsUse of MRIReview of systemsGreater frequencyPropensity-score matchingExamination findingsRetrospective studyED readmissionMedical historyHead CTClinical impactMRI examinationsBrain MRINeck CTADizzinessPatients
2022
Reduced blood-brain barrier penetration of acne vulgaris antibiotic sarecycline compared to minocycline corresponds with lower lipophilicity
Grada A, Del Rosso J, Moore A, Gold L, Harper J, Damiani G, Shaw K, Obagi S, Salem R, Tanaka S, Bunick C. Reduced blood-brain barrier penetration of acne vulgaris antibiotic sarecycline compared to minocycline corresponds with lower lipophilicity. Frontiers In Medicine 2022, 9: 1033980. PMID: 36569144, PMCID: PMC9773825, DOI: 10.3389/fmed.2022.1033980.Peer-Reviewed Original ResearchAdverse eventsClinical trialsVestibular side effectsBlood-brain barrier penetrationSecond-generation tetracyclineNon-clinical studiesLower ratesH postdosingAcne vulgarisSide effectsMinocyclineBrain samplesPotential associationSarecyclineBarrier penetrationDoxycyclineTrialsLow lipophilicityPenetranceTetracyclineDizzinessVertigoPostdosingRosaceaAcneRimegepant, Ubrogepant, and Lasmiditan in the Acute Treatment of Migraine Examining the Benefit-Risk Profile Using Number Needed to Treat/Harm
Johnston K, Powell L, Popoff E, Harris L, Croop R, Coric V, L’Italien G. Rimegepant, Ubrogepant, and Lasmiditan in the Acute Treatment of Migraine Examining the Benefit-Risk Profile Using Number Needed to Treat/Harm. The Clinical Journal Of Pain 2022, 38: 680-685. PMID: 36125279, PMCID: PMC9555761, DOI: 10.1097/ajp.0000000000001072.Peer-Reviewed Original ResearchConceptsBenefit-risk profilePain freedomPain reliefAcute treatmentRisk differenceMost bothersome symptomsSustained pain reliefFixed-effect Bayesian NMALasmiditan 200Lasmiditan 50Lowest NNTPooled placeboBothersome symptomsBayesian NMAClinical trialsSafety outcomesLasmiditanNauseaDizzinessTrialsPlaceboMigraineNNTTreatmentHoursAntibiotic Resistance Risk with Oral Tetracycline Treatment of Acne Vulgaris
Swallow MA, Fan R, Cohen JM, Bunick CG. Antibiotic Resistance Risk with Oral Tetracycline Treatment of Acne Vulgaris. Antibiotics 2022, 11: 1032. PMID: 36009899, PMCID: PMC9405006, DOI: 10.3390/antibiotics11081032.Peer-Reviewed Original ResearchAcne vulgarisSevere acne vulgarisAntibiotic resistancePotential side effectsOral tetracyclineGut dysbiosisPatients 9Gastrointestinal upsetRisk of resistanceSide effectsDrug AdministrationTetracycline treatmentSarecyclineTetracycline usageAcneTreatmentTetracyclineAntibiotic resistance riskPathogenic bacteriumRiskVulgarisDizzinessVertigoDysbiosisMinocycline
2021
Pilot MRI-based strategies to improve the detection of stroke in patients with dizziness/vertigo
Tu LH, Mahajan A, Minja FJ, Navaratnam D, Melnick ER. Pilot MRI-based strategies to improve the detection of stroke in patients with dizziness/vertigo. Clinical Imaging 2021, 82: 234-236. PMID: 34902799, DOI: 10.1016/j.clinimag.2021.12.001.Peer-Reviewed Original ResearchConceptsDizziness/vertigoCT/CTAPosterior strokeNon-specific complaintsEmergency department practiceSuch patientsPosterior circulationStroke evaluationDetection of strokeFalse reassuranceConventional MRIStrokePatientsMRIVertigoDepartment practiceHigh rateSpecialized MRICTALow sensitivityDizzinessComplaintsCT
2019
More Than Just Teenage Angst?
Leviter J, Constantine E. More Than Just Teenage Angst? Clinical Pediatric Emergency Medicine 2019, 20: 100730. DOI: 10.1016/j.cpem.2019.100730.Peer-Reviewed Original Research
2016
Can a simple question predict prolonged uroflow lag times in children?
Franco I, Grantham EC, Cubillos J, Franco J, Collett-Gardere T, Zelkovic P. Can a simple question predict prolonged uroflow lag times in children? Journal Of Pediatric Urology 2016, 12: 157.e1-157.e8. PMID: 26875871, DOI: 10.1016/j.jpurol.2015.12.009.Peer-Reviewed Original ResearchConceptsBladder neck dysfunctionNeck dysfunctionAutonomic dysfunctionPsychiatric problemsPrevalence of dizzinessTilt table testingBlood pressure dropFamily membersExperienced syncopeUroflowmetry findingsBladder dysfunctionInstitute Review BoardMale patientsMedian ageFemale patientsQuestionnaire groupDizzinessNew patientsPsychiatric historyNeuropsychiatric problemsPatientsDysfunctionUrology officeReliable markerSignificant association
2011
Somatic and autonomic small fiber neuropathy induced by bortezomib therapy: an immunofluorescence study
Giannoccaro M, Donadio V, Gomis Pèrez C, Borsini W, Di Stasi V, Liguori R. Somatic and autonomic small fiber neuropathy induced by bortezomib therapy: an immunofluorescence study. Neurological Sciences 2011, 32: 361-363. PMID: 21290160, DOI: 10.1007/s10072-010-0475-2.Peer-Reviewed Original ResearchConceptsSmall fiber neuropathySensory axonal neuropathySkin nerve fibersMajor side effectsNew chemotherapeutic agentsMeans of immunofluorescencePostural dizzinessAutonomic neuropathyBortezomib therapyAutonomic symptomsUrinary disturbanceMultiple myelomaAxonal neuropathyBortezomib treatmentNerve fibersSide effectsNeuropathyChemotherapeutic agentsImmunofluorescence studiesSmall fibersBortezomibTreatmentIleusDizzinessSyncope
2001
Validation of Dizziness as a Possible Geriatric Syndrome
Kao A, Nanda A, Williams C, Tinetti M. Validation of Dizziness as a Possible Geriatric Syndrome. Journal Of The American Geriatrics Society 2001, 49: 72-75. PMID: 11207845, DOI: 10.1046/j.1532-5415.2001.49012.x.Peer-Reviewed Original ResearchConceptsReports of dizzinessRisk factorsGeriatric syndromesOlder personsClinic-based cohortCharacteristics of patientsSeverity of dizzinessCommunity-based cohortPopulation-based studyClinic-based populationCross-sectional studyPhysical examination dataEligible patientsPostural hypotensionMore medicationsMultifactorial interventionOlder patientsMedical historyMyocardial infarctionDizzinessMultifactorial etiologyDepressive symptomsAbnormal balancePatientsDiscrete disease
2000
Health, Functional, and Psychological Outcomes Among Older Persons with Chronic Dizziness
Tinetti M, Williams C, Gill T. Health, Functional, and Psychological Outcomes Among Older Persons with Chronic Dizziness. Journal Of The American Geriatrics Society 2000, 48: 417-421. PMID: 10798469, DOI: 10.1111/j.1532-5415.2000.tb04700.x.Peer-Reviewed Original ResearchConceptsSelf-rated healthChronic dizzinessDepressive symptomsInstrumental activitiesDaily livingOlder personsProspective cohort studyGoals of carePotential confounding factorsCohort studyAdverse outcomesDizzinessAge 72Clinical strategiesBaseline levelsConfounding factorsSocial disabilityDiscrete diseaseSymptomsHealth conditionsMarginal significanceHospitalizationSyncopeOutcomesPsychological outcomesDizziness among older adults: a possible geriatric syndrome.
Tinetti M, Williams C, Gill T. Dizziness among older adults: a possible geriatric syndrome. Annals Of Internal Medicine 2000, 132: 337-44. PMID: 10691583, DOI: 10.7326/0003-4819-132-5-200003070-00002.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnxietyConnecticutCross-Sectional StudiesDepressionDizzinessDrug-Related Side Effects and Adverse ReactionsFemaleHearing DisordersHumansHypotension, OrthostaticMaleMyocardial InfarctionPostural BalancePrevalenceRisk FactorsSensation DisordersStatistics as TopicSyndromeConceptsAdjusted relative riskGeriatric syndromesRelative riskEpisodes of dizzinessCommunity-living personsPast myocardial infarctionCross-sectional studyYears of agePostural hypotensionMore medicationsMyocardial infarctionImpaired balanceDizzinessDepressive symptomsSyndromeImpaired hearingSpecific causesOlder adultsMultiple causesSymptomsProbability sampleRiskSensationCauseNew Haven
1989
Fluoxetine Overdose in an Adolescent
RIDDLE M, BROWN N, DZUBINSKI D, JETMALANI A, LAW Y, WOOLSTON J. Fluoxetine Overdose in an Adolescent. Journal Of The American Academy Of Child & Adolescent Psychiatry 1989, 28: 587-588. PMID: 2788642, DOI: 10.1097/00004583-198907000-00019.Peer-Reviewed Original Research
1985
Autonomic dysfunction, peripheral neuropathy, and depression
Rimar S, Shaywitz S, Shaywitz B, Lister G, Anderson G, Leckman J, Cohen D. Autonomic dysfunction, peripheral neuropathy, and depression. Pediatric Neurology 1985, 1: 120-123. PMID: 2854734, DOI: 10.1016/0887-8994(85)90049-9.Peer-Reviewed Original ResearchConceptsAutonomic dysfunctionPeripheral neuropathyNerve conduction velocitySural nerve biopsyCSF protein concentrationPeripheral noradrenergic systemsNerve biopsyBlood pressureNorepinephrine concentrationsNeurochemical findingsCSF concentrationsUnreported entityLower extremitiesNoradrenergic systemVibratory sensationConduction velocityMetabolic screeningAffective disordersNeuropathyDysfunctionDepressionProtein concentrationDysesthesiaDizzinessDemyelination
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