2025
Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications
Sailer A, Latich I, Levey A. Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications. Seminars In Interventional Radiology 2025, 42: 205-212. PMCID: PMC12077947, DOI: 10.1055/s-0045-1804492.Peer-Reviewed Original ResearchQuality of lifePain managementCombination of therapiesImprove quality of lifeIncreased healthcare costsOpioid consumptionAdjunctive therapyHealthcare costsPatient's painUncontrolled painPhysical sufferingPainPotential complicationsAnatomical considerationsCryoneurolysisAbstract PainImprove qualityPatient outcomesPatientsClinical settingPerson's abilityCritical anatomyPatient pathologyTherapyPersonsResearch Priorities in Neuropalliative Care
Lau W, Fehnel C, Macchi Z, Mehta A, Auffret M, Bogetz J, Fleisher J, Graber J, Leeper H, Manglani-Terranova H, Muehlschlegel S, Mroz E, Pedowitz E, Ramanathan U, Sarmet M, Shlobin N, Sokol L, Weeks S, Xu J, Medsger H, Creutzfeldt C, Vranceanu A, Zahuranec D, Hwang D. Research Priorities in Neuropalliative Care. JAMA Neurology 2025, 82: 295-302. PMID: 39899319, DOI: 10.1001/jamaneurol.2024.4932.Peer-Reviewed Original ResearchConceptsNeuropalliative careCare partnersIntegration of palliative careSpecialty palliative care servicesGoal-concordant carePalliative care servicesInterdisciplinary panel of expertsArea of practiceImprove quality of lifeQuality of lifePalliative careCare interventionsCare servicesPanel of expertsDelivery modelsPriority research areasCareInterdisciplinary panelImprove qualityCare SocietyResearch prioritiesResearch funding mechanismsResearch CommitteeSpecialized communicationNeurological diseasesQualitative analysis of pain impact in adult patients with X-linked hypophosphatemia
Nishime N, Theriault C, Feinn R, Macica C. Qualitative analysis of pain impact in adult patients with X-linked hypophosphatemia. JBMR Plus 2025, 9: ziaf012. PMID: 40060917, PMCID: PMC11890110, DOI: 10.1093/jbmrpl/ziaf012.Peer-Reviewed Original ResearchHealth-related quality of lifeQuality of lifeDomains of health-related quality of lifePain self-management interventionShort Form Survey InstrumentX-linked hypophosphatemiaEffective pain management strategiesSelf-management interventionsHealthcare providers' lackHealth-related qualityPain management strategiesExperiences of adultsImprove quality of lifeAge-adjusted differencesSemi-structured interviewsPhysical inactivityProviders' lackQualitative analysis of interviewsHealthcare accessPhysical functionImprove carePhysical therapyEmotional burdenSF-36Healthcare services10 Dysmenorrhea and endometriosis in the adolescent female
Davis-Kankanamge C, Vash-Margita A. 10 Dysmenorrhea and endometriosis in the adolescent female. 2025, 86-98. DOI: 10.1016/b978-0-443-10512-8.00019-9.Peer-Reviewed Original ResearchPelvic painCause of secondary dysmenorrheaTreatment of pelvic painGonadotropin-releasing hormone agonistQuality of lifeCombination of estrogenDevelopment of treatment modalitiesDiagnosis of endometriosisDevelopment of noninvasive biomarkersTreatment of endometriosisNonsteroidal antiinflammatory drugsImpaired quality of lifeRetrograde blood flowMedical treatment regimensNeuropathic medicationsOvarian pathologySecondary dysmenorrheaHistological diagnosisHormone agonistSurgical treatmentImprove quality of lifeTreatment modalitiesTreatment regimensAdolescent patientsAntiinflammatory drugs
2024
IMPLEMENTATION OF COMMUNITY-BASED PALLIATIVE CARE: A SYSTEMATIC SCOPING REVIEW
Ho D, Dissault N, Vick J, Skalla L, Dukkipati H, Ma J, Kaufman B. IMPLEMENTATION OF COMMUNITY-BASED PALLIATIVE CARE: A SYSTEMATIC SCOPING REVIEW. Innovation In Aging 2024, 8: 233-233. PMCID: PMC11689857, DOI: 10.1093/geroni/igae098.0753.Peer-Reviewed Original ResearchCommunity-based palliative carePalliative careSystematic scoping reviewPerceived barriersScoping reviewProvider perspectiveEnd-of-life careSocial needs resourcesLeadership buy-inInter-provider communicationEnd-of-lifeReviewers screened articlesImprove quality of lifeQuality of lifePC teamIllness carePC educationCare partnersFramework synthesisProvider levelCategorize themesPractice settingsSpecialty clinicsNeeds resourcesProgram implementationPain can’t be carved at the joints: defining function-based pain profiles and their relevance to chronic disease management in healthcare delivery design
Barron D, Saltoun K, Kiesow H, Fu M, Cohen-Tanugi J, Geha P, Scheinost D, Isaac Z, Silbersweig D, Bzdok D. Pain can’t be carved at the joints: defining function-based pain profiles and their relevance to chronic disease management in healthcare delivery design. BMC Medicine 2024, 22: 594. PMID: 39696368, PMCID: PMC11656997, DOI: 10.1186/s12916-024-03807-z.Peer-Reviewed Original ResearchConceptsChronic diseasesPain ProfileChronic conditionsPatient functionPain conditionsManagement of chronic diseasesChronic disease managementContinuum of careHealthcare delivery systemImprove quality of lifeQuality of lifePainful body partPain interferenceAssociated with clinical variablesUK BiobankWhole-body perspectiveHealth strategiesTreatment of individual patientsPain intensityClinically relevant differencesPatient wellbeingPain managementTreat painful conditionsICD codesMedical specialtiesComparative proteomic analysis of human vitreous in rhegmatogenous retinal detachment and diabetic retinopathy reveals a common pathway and potential therapeutic target
Brighenti T, Neri G, Mazzola M, Tomé G, Scalfati M, Peroni D, Belli R, Zampedri E, Tebaldi T, Borello U, Romanelli F, Casarosa S. Comparative proteomic analysis of human vitreous in rhegmatogenous retinal detachment and diabetic retinopathy reveals a common pathway and potential therapeutic target. Clinical Proteomics 2024, 21: 63. PMID: 39609746, PMCID: PMC11603643, DOI: 10.1186/s12014-024-09515-3.Peer-Reviewed Original ResearchRhegmatogenous retinal detachmentDiabetic retinopathyNon-steroidal anti-inflammatory drugsRetinal detachmentVitreoretinal diseasesPotential therapeutic targetProliferative vitreoretinopathyOphthalmic non-steroidal anti-inflammatory drugTherapeutic targetAnalysis of vitreous samplesProteomic signatureGlucose metabolismNitric oxide levelsAnti-inflammatory drugsElevated nitric oxide levelsMacular puckerPhotoreceptor deathImprove quality of lifeAldo-keto reductase family 1 member B1Vitreous samplesRetinal cellsVascular proliferationFibrous proliferationReduce complicationsHuman vitreousThe effects of a psychoeducational intervention on caregivers of colorectal cancer patients: A meta-analysis of randomized controlled trials
Zhang M, Xue Y, Shao M, Yang Y, Yu L, Ma B, Li D, Zhou H, Wang K, Chen C, Cheng M, Wang T. The effects of a psychoeducational intervention on caregivers of colorectal cancer patients: A meta-analysis of randomized controlled trials. European Journal Of Oncology Nursing 2024, 74: 102739. PMID: 39729814, DOI: 10.1016/j.ejon.2024.102739.Peer-Reviewed Original ResearchConceptsPsychoeducational interventionRandomized controlled trialsPsychological statusImpact of psychoeducational interventionsAspects of caregivingReduce caregiver burdenControlled trialsEnhancing caregivers' abilityCondition of caregiversImprove quality of lifeQuality of lifeCaregiver burdenCRC patientsRandom-effects modelCaregivers' abilityCINAHL CompletePerception of family supportGeneral well-beingActive lifestyleWeb of ScienceMeta-analysis of randomized controlled trialsPhysical healthCare scheduleSocial supportFixed-effects modelTop Ten Tips Palliative Care Clinicians Should Know About Addressing Patient Sexuality and Intimacy in Serious Illness
Chammas D, Shindel A, Rowen T, Schanche K, Wittmann D, Shalev D, D’Addario J, Wisniewski R, Scheel T, Nelson C, Ratner E, Rosa W, Rabow M. Top Ten Tips Palliative Care Clinicians Should Know About Addressing Patient Sexuality and Intimacy in Serious Illness. Journal Of Palliative Medicine 2024 PMID: 39588705, DOI: 10.1089/jpm.2024.0451.Peer-Reviewed Original ResearchPalliative careQuality of lifePatients' sexualityDimensions of quality of lifePalliative care cliniciansEvidence-based tipsImprove quality of lifeCare cliniciansBiopsychosocial modelSerious illnessSexual healthOpen discussionSocial workIllnessCliniciansNursesCareIntimacySexualityHealthInterventionPatientsOncologyPsychiatryGynecologyBridging the gap: strategies for recognizing and managing post-COVID conditions
Khan M, Becker R. Bridging the gap: strategies for recognizing and managing post-COVID conditions. Frontiers In Medicine 2024, 11: 1395420. PMID: 39635598, PMCID: PMC11615723, DOI: 10.3389/fmed.2024.1395420.Peer-Reviewed Original ResearchQuality of lifePost-COVID conditionsTargeted interventionsPrevalence of chronic conditionsStandardized screening toolPatient-centered approachPrevalence of post-COVID conditionImprove quality of lifeHigh-risk individualsPsychosocial healthHealthcare providersChronic conditionsCardiovascular healthEarly diagnosisImprove qualityScreening toolPeripheral vascular diseaseCommunity leadersComorbid conditionsDevelopment of screening strategiesPersistent symptomsCost-effective screening approachHealthAffected individualsInterventionHypofractionated vs Conventionally Fractionated Postmastectomy Radiation After Implant-Based Reconstruction
Wong J, Uno H, Tramontano A, Fisher L, Pellegrini C, Abel G, Burstein H, Chun Y, King T, Schrag D, Winer E, Bellon J, Cheney M, Hardenbergh P, Ho A, Horst K, Kim J, Leonard K, Moran M, Park C, Recht A, Soto D, Shiloh R, Stinson S, Snyder K, Taghian A, Warren L, Wright J, Punglia R. Hypofractionated vs Conventionally Fractionated Postmastectomy Radiation After Implant-Based Reconstruction. JAMA Oncology 2024, 10: 1370-1378. PMID: 39115975, PMCID: PMC11310844, DOI: 10.1001/jamaoncol.2024.2652.Peer-Reviewed Original ResearchFunctional Assessment of Cancer Therapy-BreastPhysical well-beingPostmastectomy radiation therapyImplant-based reconstructionConventional fractionationStudy armsPhysical well-being scoresUS cancer centersLocal-regional disease controlImprove quality of lifeQuality of lifeAs-treated cohortChest wall doseHigher adverse eventsToxic effectsMain OutcomesRandomized clinical trialsPWB scoreUnpaid timePostmastectomy radiationImplant reconstructionRadiation therapyTreatment breaksImplant-basedImprovement changes51856 Spesolimab rapidly improves quality of life in patients with generalized pustular psoriasis, as per Dermatology Life Quality Index scores: Data from the Effisayil 2 trial
Gottlieb A, Strober B, Kokolakis G, Merola J, Zheng M, Langley R, Tang M, Hofmann P, Thoma C, Warren R. 51856 Spesolimab rapidly improves quality of life in patients with generalized pustular psoriasis, as per Dermatology Life Quality Index scores: Data from the Effisayil 2 trial. Journal Of The American Academy Of Dermatology 2024, 91: ab316. DOI: 10.1016/j.jaad.2024.07.1256.Peer-Reviewed Original ResearchImprove quality of lifeQuality of lifeCost‐effectiveness of sutimlimab in cold agglutinin disease
Ito S, Wang D, Purcell A, Chetlapalli K, Lee A, Cuker A, Goshua G. Cost‐effectiveness of sutimlimab in cold agglutinin disease. American Journal Of Hematology 2024, 99: 1475-1484. PMID: 38733355, DOI: 10.1002/ajh.27358.Peer-Reviewed Original ResearchPrimary cold agglutinin diseaseCold agglutinin diseaseStandard-of-careIncremental cost-effectiveness ratioUS willingness-to-pay thresholdRare autoimmune hemolytic anemiaPhase 3 studyWillingness-to-pay thresholdsAutoimmune hemolytic anemiaTime-limited treatmentHuman monoclonal antibodyCold-reactive antibodiesBinding to red blood cellsFollow-up dataCost-effectiveness ratioComplement-mediated hemolysisDeterministic sensitivity analysisHealth resource utilizationProbabilistic sensitivity analysesTransfusion-dependentClinical remissionTransfusion supportImprove quality of lifeRed blood cellsHemolytic anemiaClinical activity, pharmacokinetics, and pharmacodynamics of oral hypomethylating agents for myelodysplastic syndromes/neoplasms and acute myeloid leukemia: A multidisciplinary review
Haumschild R, Kennerly-Shah J, Barbarotta L, Zeidan A. Clinical activity, pharmacokinetics, and pharmacodynamics of oral hypomethylating agents for myelodysplastic syndromes/neoplasms and acute myeloid leukemia: A multidisciplinary review. Journal Of Oncology Pharmacy Practice 2024, 30: 721-736. PMID: 38509812, PMCID: PMC11118786, DOI: 10.1177/10781552241238979.Peer-Reviewed Original ResearchOral hypomethylating agentsAcute myeloid leukemiaHypomethylating agentsPK-PD profilesPharmacokinetic (PK)-pharmacodynamicMyeloid leukemiaTreatment selectionPK-PDConcentration-time curveIntravenous (IVImprove treatment outcomesCC-486IV decitabineOral azacitidineMaintenance therapySubcutaneous azacitidineNo significant differenceImprove quality of lifeAzacitidineClinical trialsClinical activityTreatment outcomesDisease settingsDecitabineDisease outcomeGender-based stigma and the prevention and treatment of HIV/AIDS among older women: A scoping review protocol
Vu T, Manalel J, Nyhan K, Wang K, Monin J. Gender-based stigma and the prevention and treatment of HIV/AIDS among older women: A scoping review protocol. PLOS ONE 2024, 19: e0298024. PMID: 38330082, PMCID: PMC10852273, DOI: 10.1371/journal.pone.0298024.Peer-Reviewed Original ResearchConceptsGender-based stigmaFull-text articlesOlder womenHIV preventionHIV care engagementStandardized data collection formPreferred Reporting ItemsImprove quality of lifeData collection formManagement of HIVPopulation of womenQuality of lifePeer-reviewed publicationsCare engagementCare experiencesWeb of ScienceTreatment of HIV/AIDSHealthcare providersNarrative summaryPRISMA-ScRSupplementary screeningSynthesize evidenceReporting ItemsCitation chainingCollection formDisparities in care of older adults of color with cancer: A narrative review
Dotan E, Lynch S, Ryan J, Mitchell E. Disparities in care of older adults of color with cancer: A narrative review. Cancer Medicine 2024, 13: e6790. PMID: 38234214, PMCID: PMC10905558, DOI: 10.1002/cam4.6790.Peer-Reviewed Original ResearchSocial determinants of healthOlder adultsGeriatric assessmentDeterminants of healthCancer incidence ratesOlder adults of colorLimited social supportImprove quality of lifeDecreased functional statusQuality of lifeOlder white patientsAge-related challengesPatients of colorAdults of colorSocial determinantsHealthcare accessHealthcare providersOverall careSocial supportPatient careAge-related concernsRacial disparitiesFunctional statusIncidence rateRates of comorbiditiesPatients’ perspectives on oral decitabine/cedazuridine for the treatment of myelodysplastic syndromes/neoplasms
Zeidan A, Perepezko K, Salimi T, Washington T, Epstein R. Patients’ perspectives on oral decitabine/cedazuridine for the treatment of myelodysplastic syndromes/neoplasms. Therapeutic Advances In Hematology 2024, 15: 20406207241257313. PMID: 39091323, PMCID: PMC11292726, DOI: 10.1177/20406207241257313.Peer-Reviewed Original ResearchHypomethylating agentsDEC-CQuality of lifeHypomethylating agent therapyGuideline-recommended treatmentHMA therapyOral therapySurvey of patientsTreatment side effectsAdult patientsImprove quality of lifeUS patientsSide effectsPatientsTreatment administrationTherapyDecitabine/cedazuridineTreatmentDaily activitiesMonthsLittle/no impact
2022
Artificial intelligence in the detection of skin cancer
Beltrami E, Brown A, Salmon P, Leffell D, Ko J, Grant-Kels J. Artificial intelligence in the detection of skin cancer. Journal Of The American Academy Of Dermatology 2022, 87: 1336-1342. PMID: 35998842, DOI: 10.1016/j.jaad.2022.08.028.Peer-Reviewed Original ResearchConceptsArtificial intelligenceReduce health care costsSkin cancerHealth care costsImprove quality of lifeReducing physician concernsLimitations of AIQuality of lifeReducing unnecessary proceduresManagement of skin cancerDetection of skin cancerAI capabilitiesSkin cancer detectionPatient careSkin assessmentCare costsPhysician concernsAI technologyImprove qualityPromote greater accessUnnecessary proceduresClinical settingFundamental terminologyCancerCancer detectionThe effect of self-management online modules plus nurse-led support on pain and quality of life among young adults with irritable bowel syndrome: A randomized controlled trial
Chen J, Zhang Y, Barandouzi Z, Lee J, Zhao T, Xu W, Chen M, Feng B, Starkweather A, Cong X. The effect of self-management online modules plus nurse-led support on pain and quality of life among young adults with irritable bowel syndrome: A randomized controlled trial. International Journal Of Nursing Studies 2022, 132: 104278. PMID: 35640500, PMCID: PMC10588769, DOI: 10.1016/j.ijnurstu.2022.104278.Peer-Reviewed Original ResearchConceptsQuality of lifeImprove quality of lifeNurse-led interventionNurse-ledIntervention groupIntervention effectsPain interferenceOnline modulesImprove qualitySelf-managementNurse-led self-management programIrritable bowel syndromeYoung adultsSelf-efficacyNurse-led supportEffects of self-managementLife-long self-managementSelf-management programReducing pain interferenceSelf-reported painFollow-upIncreased quality of lifeBaseline data collectionIncreased self-efficacyDecreased pain intensity
2021
Sleep Disruption Worsens Seizures: Neuroinflammation as a Potential Mechanistic Link
Bonilla-Jaime H, Zeleke H, Rojas A, Espinosa-Garcia C. Sleep Disruption Worsens Seizures: Neuroinflammation as a Potential Mechanistic Link. International Journal Of Molecular Sciences 2021, 22: 12531. PMID: 34830412, PMCID: PMC8617844, DOI: 10.3390/ijms222212531.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep deprivationAnti-epileptic drugsEpilepsy-related mortalitySudden unexpected deathPotential mechanistic linkSleep apneaImprove quality of lifeWorsen neurodegenerationDaytime sleepinessDisease progressionSeizure frequencySeizure activityNocturnal seizuresSide effectsQuality of lifeUnexpected deathEpileptic brainSeizuresEpilepsy patientsPoor sleep qualityEpilepsyNeuroinflammationSleep disturbanceMechanistic link
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