2025
Evaluating clinical and pathologic predictors for pathologic lymph node positivity (pN+) in patients with clinical T1-4N0M0 bladder cancer undergoing cystectomy.
Jaime-Casas S, Barragan-Carrillo R, Zugman M, Zang P, Ebrahimi H, Castro D, Mercier B, Li X, Dizman N, Salgia N, Hsu J, Nguyen C, Yip W, Chehrazi-Raffle A, Zengin Z, Meza L, Pal S, Tripathi A. Evaluating clinical and pathologic predictors for pathologic lymph node positivity (pN+) in patients with clinical T1-4N0M0 bladder cancer undergoing cystectomy. Journal Of Clinical Oncology 2025, 43: 877-877. DOI: 10.1200/jco.2025.43.5_suppl.877.Peer-Reviewed Original ResearchConcomitant carcinoma in situRecurrence-free survivalPositive surgical marginsLymph node positivityRadical cystectomyLymphovascular invasionOverall survivalPreoperative hydronephrosisSurgical marginsPathologic predictorsBladder cancerPredictors of lymph node positivityConcomitant CISMultivariate analysisPathologic lymph node positivityPelvic lymph node dissectionPathological lymph node involvementMultivariate Cox proportional hazards modelMultivariate Cox regression modelNode-positiveBladder-preserving approachPreoperative renal functionLymph node dissectionLymph node involvementCarcinoma in situ
2024
Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017–2019
Girardi M, Carlson K, Huang X, Corman S, Edmundson P, Schmier J, Kale H, Raina R, Foss F. Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017–2019. Journal Of Dermatological Treatment 2024, 35: 2360568. PMID: 38852942, DOI: 10.1080/09546634.2024.2360568.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaCutaneous T-cell lymphoma patientsExtracorporeal photopheresisResponse rateClinical outcomesMonths of ECP treatmentMedian time to responseReal-world treatment patternsECP initiationLymph node involvementStage IV diseaseAdvanced-stage diseaseT-cell lymphomaTime to responseEffective treatment optionPercentage of patientsChart review studyIV diseaseSezary syndromeNode involvementConcomitant therapySystemic therapyMedian ageMycosis fungoidesChart reviewImmediate DIEP Breast Reconstruction in a Trans Woman with Breast Cancer
Avery E, Barone N, Haykal S. Immediate DIEP Breast Reconstruction in a Trans Woman with Breast Cancer. Plastic & Reconstructive Surgery Global Open 2024, 12: e5834. PMID: 38798942, PMCID: PMC11124744, DOI: 10.1097/gox.0000000000005834.Peer-Reviewed Original ResearchImmediate breast reconstructionBreast reconstructionBreast cancerEstrogen therapyRisk of breast cancerTrans womenBilateral skin-sparing mastectomyDeep inferior epigastric perforator free flapHistory of estrogen therapySentinel lymph node biopsyManagement of breast cancerDIEP breast reconstructionPostoperative flap complicationsSkin-sparing mastectomyLymph node biopsyLymph node involvementRight breast cancerInvasive mucinous carcinomaBreast cancer diagnosisFree flap reconstructionBreast cancer managementHolistic treatment approachPerforator free flapFinal pathologyNode biopsy
2023
Association of Wildfire Exposure While Recovering From Lung Cancer Surgery With Overall Survival
Zhang D, Xi Y, Boffa D, Liu Y, Nogueira L. Association of Wildfire Exposure While Recovering From Lung Cancer Surgery With Overall Survival. JAMA Oncology 2023, 9: 1214-1220. PMID: 37498574, PMCID: PMC10375383, DOI: 10.1001/jamaoncol.2023.2144.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerOverall survivalWorse overall survivalLung cancerNSCLC surgeryCohort studyHazard ratioSurgical resectionNSCLC resectionLong-term overall survivalNational Cancer DatabaseLung cancer surgeryLymph node involvementCell lung cancerHealth insurance typeHealth hazardsHospital dischargeNode involvementCancer surgeryStudy endTumor sizeCancer DatabaseInsurance typeHigh riskUnexposed individuals
2021
Association between percentage of positive biopsy cores and risk of pelvic lymph node involvement in prostate cancer.
Yang D, Dee E, Arega M, Nguyen P, Orio P, King M, Kann B, Yu J, Cook K, Ma T, Kishan A, Muralidhar V. Association between percentage of positive biopsy cores and risk of pelvic lymph node involvement in prostate cancer. Journal Of Clinical Oncology 2021, 39: 205-205. DOI: 10.1200/jco.2021.39.6_suppl.205.Peer-Reviewed Original ResearchPercentage of positive biopsy coresRisk of pelvic lymph node involvementPelvic lymph node involvementLymph node involvementPositive biopsy coresPelvic lymph nodesProstate cancerRadical prostatectomyBiopsy coresNode involvementLymph nodesDefinitive treatment of prostate cancerGleason 9-10 diseasePositive pelvic lymph nodesTreatment of prostate cancerBiopsy Gleason scoreClinicopathological prognostic variablesElective nodal irradiationGleason 8 diseasePathologic nodal evaluationClinical tumor stageNational Cancer DatabaseTime of RPClinically relevant associationMultivariate logistic regressionExamination of factors associated with lymph node metastases in lung carcinoids: Results from a single institution retrospective cohort study
Pathipati MP, Yohannan TK, Tian L, Hornbacker K, Benson JA, Berry GJ, Lui NS, Kunz PL, Padda SK. Examination of factors associated with lymph node metastases in lung carcinoids: Results from a single institution retrospective cohort study. Lung Cancer 2021, 154: 186-194. PMID: 33551175, PMCID: PMC8026717, DOI: 10.1016/j.lungcan.2021.01.017.Peer-Reviewed Original ResearchConceptsLung neuroendocrine tumorsLymph nodesNeuroendocrine tumorsLung carcinoidsSSTR imagingLN metastasisAtypical carcinoidExact testSingle-institution retrospective cohort studyLymph node-positive diseaseAssociation of lymphPositive lymph nodesRetrospective cohort studyLymph node diseaseLymph node involvementNode-positive diseaseLymph node metastasisMultivariable logistic regressionFisher's exact testPre-operative workupN2 diseaseAdjuvant therapyLN involvementN1 diseaseNode involvement
2020
Association Between Percentage of Positive Biopsy Cores and Risk of Pelvic Lymph Node Involvement in Prostate Cancer
Yang D, Dee E, Arega M, Nguyen P, Orio P, King M, Kann B, Yu J, Sandler K, Ma T, Kishan A, Muralidhar V. Association Between Percentage of Positive Biopsy Cores and Risk of Pelvic Lymph Node Involvement in Prostate Cancer. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: e860. DOI: 10.1016/j.ijrobp.2020.07.427.Peer-Reviewed Original ResearchOutcomes of Patients with Transformed Mycosis Fungoides: Analysis from a Prospective Multicenter US Cohort Study
Lansigan F, Horwitz SM, Pinter-Brown LC, Carson KR, Shustov AR, Rosen ST, Pro B, Hsi ED, Federico M, Gisselbrecht C, Schwartz M, Bellm LA, Acosta M, Foss FM. Outcomes of Patients with Transformed Mycosis Fungoides: Analysis from a Prospective Multicenter US Cohort Study. Clinical Lymphoma Myeloma & Leukemia 2020, 20: 744-748. PMID: 32532611, PMCID: PMC8447249, DOI: 10.1016/j.clml.2020.05.001.Peer-Reviewed Original ResearchConceptsLymph node involvementOutcomes of patientsMedian survivalNode involvementCohort studyMycosis fungoidesSingle agentPeripheral T-cell lymphoma patientsT-cell lymphoma patientsProspective cohort studyKaplan-Meier methodologyUS cohort studyNovel treatment approachesConcomitant radiotherapyMost patientsSystemic therapyMedian agePatient characteristicsMedian timeLymphoma patientsLiposomal doxorubicinPatientsTreatment approachesSurvival rateLactate dehydrogenaseRecurrence and Complications in Pediatric and Adolescent Papillary Thyroid Cancer in a High-Volume Practice
Rubinstein JC, Herrick-Reynolds K, Dinauer C, Morotti R, Solomon D, Callender GG, Christison-Lagay ER. Recurrence and Complications in Pediatric and Adolescent Papillary Thyroid Cancer in a High-Volume Practice. Journal Of Surgical Research 2020, 249: 58-66. PMID: 31923715, DOI: 10.1016/j.jss.2019.12.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsChildFemaleFollow-Up StudiesHospitals, High-VolumeHumansLymph NodesLymphatic MetastasisMaleNeoplasm Recurrence, LocalPostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSurvival AnalysisThyroid Cancer, PapillaryThyroid GlandThyroid NeoplasmsThyroidectomyTreatment OutcomeYoung AdultConceptsPediatric papillary thyroid cancerLateral neck diseaseNeck diseasePapillary thyroid cancerNode involvementThyroid cancerExact testLymph node involvementCentral neck dissectionExtent of diseasePredictors of recurrenceRetrospective case seriesNon-Caucasian raceCox proportional hazardsLateral node involvementHigh-volume practiceFisher's exact testDisease recurrenceLymphovascular invasionMedian ageNeck dissectionCase seriesIndependent predictorsRetrospective reviewTumor size
2019
Impact of contralateral lymph nodal involvement and extranodal extension on survival of surgically managed HPV-positive oropharyngeal cancer staged with the AJCC eighth edition
Miccio JA, Verma V, Kelly J, Kann BH, An Y, Park HS, Eskander A, Burtness B, Husain Z. Impact of contralateral lymph nodal involvement and extranodal extension on survival of surgically managed HPV-positive oropharyngeal cancer staged with the AJCC eighth edition. Oral Oncology 2019, 99: 104447. PMID: 31630059, DOI: 10.1016/j.oraloncology.2019.104447.Peer-Reviewed Original ResearchConceptsOropharyngeal squamous cell carcinomaExtranodal extensionLymphovascular invasionKaplan-Meier overall survival analysisContralateral lymph node involvementHPV-positive oropharyngeal cancerFuture staging systemsNational Cancer DatabaseLymph node involvementLymph nodal involvementSquamous cell carcinomaAJCC eighth editionOverall survival analysisPathologic nodalInferior OSNodal involvementNode involvementWorse OSClinical stagingPrognostic factorsOropharyngeal cancerPositive marginsPrognostic importanceCell carcinomaCox regressionOA01 Impact of Contralateral Lymph Node Involvement on Survival of Surgically-Managed HPV-Positive Oropharyngeal Cancer Staged with the AJCC Eighth Edition
Miccio J, Kelly J, Kann B, An Y, Park H, Verma V, Mehra S, Judson B, Burtness B, Husain Z. OA01 Impact of Contralateral Lymph Node Involvement on Survival of Surgically-Managed HPV-Positive Oropharyngeal Cancer Staged with the AJCC Eighth Edition. International Journal Of Radiation Oncology • Biology • Physics 2019, 103: e1. DOI: 10.1016/s0360-3016(19)30402-x.Peer-Reviewed Original ResearchClinical risk-based associations of lymph node dissection and detection of metastasis among men treated with radical prostatectomy.
Abello A, Kenney P, Leapman M. Clinical risk-based associations of lymph node dissection and detection of metastasis among men treated with radical prostatectomy. Journal Of Clinical Oncology 2019, 37: 284-284. DOI: 10.1200/jco.2019.37.7_suppl.284.Peer-Reviewed Original ResearchPelvic lymph node dissectionLymph node countLymph node dissectionLymph node yieldRadical prostatectomyRisk strataNode dissectionNode yieldProstate Risk Assessment (CAPRA) scoreConditional logistic regression modelsRisk statusNational Cancer DatabaseHigh-risk patientsLymph node involvementProportion of patientsGroup of patientsLymph node metastasisDetection of metastasesCancer detection rateClinical risk statusRisk assessment scoreNode countLogistic regression modelsNode involvementPathologic factors
2018
Trends and outcomes of lymphadenectomy for nonmetastatic renal cell carcinoma: A propensity score-weighted analysis of the National Cancer Database
Farber NJ, Rivera-Núñez Z, Kim S, Shinder B, Radadia K, Sterling J, Modi PK, Goyal S, Parikh R, Mayer TM, Weiss RE, Kim IY, Elsamra SE, Jang TL, Singer EA. Trends and outcomes of lymphadenectomy for nonmetastatic renal cell carcinoma: A propensity score-weighted analysis of the National Cancer Database. Urologic Oncology Seminars And Original Investigations 2018, 37: 26-32. PMID: 30446458, PMCID: PMC6295174, DOI: 10.1016/j.urolonc.2018.10.004.Peer-Reviewed Original ResearchConceptsLymph node dissectionNonmetastatic renal cell carcinomaRenal cell carcinomaMedian overall survivalNational Cancer DatabaseOverall survivalCell carcinomaCancer DatabasePropensity score-weighted analysisLow-stage diseaseLN-positive patientsLymph node involvementCox regression analysisSubgroup of patientsT stages 1Contemporary practice patternsRegression analysisChi-square testOS benefitPotential overutilizationNode dissectionUnderwent surgeryNode involvementPatient demographicsPositive patientsPredictors of Lymph Node Involvement by Soft Tissue Sarcoma: An Analysis of the National Cancer Database (NCDB)
Miccio J, Jairam V, Gao S, Augustyn A, Oladeru O, Onderdonk B, Costa J, Han D, Khan S, Friedlaender G, Lindskog D, Deshpande H, Tara H, Osborn H, Roberts K, Patel K. Predictors of Lymph Node Involvement by Soft Tissue Sarcoma: An Analysis of the National Cancer Database (NCDB). International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e335. DOI: 10.1016/j.ijrobp.2018.07.1028.Peer-Reviewed Original ResearchApplication of the Eighth Edition of the American Joint Committee on Cancer Staging for Pancreatic Adenocarcinoma
Liu C, Cheng H, Jin K, Guo M, Lu Y, Wang Z, Yang C, Long J, Ni Q, Yu X, Luo G. Application of the Eighth Edition of the American Joint Committee on Cancer Staging for Pancreatic Adenocarcinoma. Pancreas 2018, 47: 742-747. PMID: 29851752, DOI: 10.1097/mpa.0000000000001073.Peer-Reviewed Original ResearchConceptsAmerican Joint Committee on CancerAmerican Joint Committee on Cancer stageTumor resectionPancreatic cancerEighth editionAmerican Joint Committee on Cancer eighth editionAmerican Joint Committee on Cancer seventh editionStage classificationLymph node involvementEnd Results registrySeventh editionPrognosis to patientsNode involvementTumor diameterPositive nodesInstitutional seriesPancreatic adenocarcinomaCancer stageStage distributionSurvival curvesPatientsSurvival analysisTumorStatistical differenceCancerPhenotypes of organ involvement in sarcoidosis
Schupp J, Freitag-Wolf S, Bargagli E, Mihailović-Vučinić V, Rottoli P, Grubanovic A, Müller A, Jochens A, Tittmann L, Schnerch J, Olivieri C, Fischer A, Jovanovic D, Filipovic S, Videnovic-Ivanovic J, Bresser P, Jonkers R, O'Reilly K, Ho L, Gaede K, Zabel P, Dubaniewicz A, Marshall B, Kieszko R, Milanowski J, Günther A, Weihrich A, Petrek M, Kolek V, Keane M, O'Beirne S, Donnelly S, Haraldsdottir S, Jorundsdottir K, Costabel U, Bonella F, Wallaert B, Grah C, Peroš-Golubičić T, Luisetti M, Kadija Z, Pabst S, Grohé C, Strausz J, Vašáková M, Sterclova M, Millar A, Homolka J, Slováková A, Kendrick Y, Crawshaw A, Wuyts W, Spencer L, Pfeifer M, Valeyre D, Poletti V, Wirtz H, Prasse A, Schreiber S, Krawczak M, Müller-Quernheim J. Phenotypes of organ involvement in sarcoidosis. European Respiratory Journal 2018, 51: 1700991. PMID: 29371378, DOI: 10.1183/13993003.00991-2017.Peer-Reviewed Original ResearchConceptsOrgan involvementIntrathoracic lymph node involvementAbdominal organ involvementLymph node involvementEuropean multicentre studySystemic granulomatous diseaseNew clinical phenotypeHitherto unknown etiologyAcute onsetExtrapulmonary involvementNode involvementSkin involvementFemale patientsMulticentre studyDisease involvementUnknown etiologyCaucasian patientsGranulomatous diseaseHomogenous cohortSarcoidosisPatientsClinical phenotypeStudy centersStandardised protocolDisease phenotypePrognostic role of lymphovascular invasion and lymph node status among breast cancer subtypes
Liao G, Hsu H, Chu C, Hong Z, Fu C, Chou Y, Golshan M, Dai M, Chen T, De-Chian C, Tsai W, Pan C, Hsu K, Kao E, Hsu Y, Chang T, Yu J. Prognostic role of lymphovascular invasion and lymph node status among breast cancer subtypes. Journal Of Medical Sciences 2018, 38: 54-61. DOI: 10.4103/jmedsci.jmedsci_105_17.Peer-Reviewed Original ResearchRecurrent-free survivalBreast cancer subtypesLymph node statusLymphovascular invasionOverall survivalImportant prognostic factorLymph nodesPrognostic factorsHuman Investigation CommitteeLuminal HER2 subtypeNode statusHER2 subtypeBreast cancerSignificant differencesCancer subtypesLymph node involvementYear of diagnosisInstitutional review board approvalKaplan-Meier analysisTriple-negative subtypeMultivariate survival analysisCox proportional hazardsDate of deathReview board approvalSignificant independent relationship
2016
Defining outcomes of patients with clinical stage I small cell lung cancer upstaged at surgery
Thomas DC, Arnold BN, Rosen JE, Salazar MC, Blasberg JD, Detterbeck FC, Boffa DJ, Kim AW. Defining outcomes of patients with clinical stage I small cell lung cancer upstaged at surgery. Lung Cancer 2016, 103: 75-81. PMID: 28024700, DOI: 10.1016/j.lungcan.2016.11.016.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantCombined Modality TherapyDatabases, FactualFemaleGuidelines as TopicHumansLung NeoplasmsLymphatic MetastasisMaleMiddle AgedNeoplasm StagingOutcome Assessment, Health CarePneumonectomyPostoperative PeriodRadiotherapySmall Cell Lung CarcinomaSurvival AnalysisConceptsStage I small cell lung cancerClinical stage ISmall cell lung cancerCell lung cancerAdjuvant chemotherapySurgical resectionPathologic upstagingStage IRadiation therapyNodal diseaseLung cancerPositive lymph node involvementNational Cancer DatabaseOutcomes of patientsLymph node involvementProportion of patientsCurative intentNodal upstagingSCLC patientsUpstaged patientsAdjuvant therapyNode involvementIndependent predictorsInferior survivalT descriptorComparative Effectiveness of Treatment Strategies for Bladder Cancer With Clinical Evidence of Regional Lymph Node Involvement
Galsky M, Stensland K, Sfakianos J, Mehrazin R, Diefenbach M, Mohamed N, Tsao C, Boffetta P, Wiklund P, Oh W, Mazumdar M, Ferket B. Comparative Effectiveness of Treatment Strategies for Bladder Cancer With Clinical Evidence of Regional Lymph Node Involvement. Journal Of Clinical Oncology 2016, 34: 2627-2635. PMID: 27269939, PMCID: PMC5012691, DOI: 10.1200/jco.2016.67.5033.Peer-Reviewed Original ResearchConceptsCombined-modality therapyLymph node involvementTreated with chemotherapyOverall survivalAdjuvant chemotherapyBladder cancerPreoperative chemotherapyNode involvementDistant metastasisChemotherapy trialsClinical evidence of regional lymph node involvementSurvival of patients treated with chemotherapyTreatment strategiesClinical lymph node involvementEvidence of regional lymph node involvementRegional lymph node involvementNational Cancer Data BasePatients treated with chemotherapyFirst-line chemotherapy trialsNeoadjuvant chemotherapy trialsTreated with cystectomyEffectiveness of treatment strategiesBladder cancer patientsLong-term survivalCystectomyComparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+).
Galsky M, Stensland K, Sfakianos J, Mehrazin R, Diefenbach M, Tsao C, Boffetta P, Oh W, Mazumdar M, Ferket B. Comparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+). Journal Of Clinical Oncology 2016, 34: 4530-4530. DOI: 10.1200/jco.2016.34.15_suppl.4530.Peer-Reviewed Original Research
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