2025
Pain Management in the Older Adults A Narrative Review
Rajput K, Ng J, Zwolinski N, Chow R. Pain Management in the Older Adults A Narrative Review. Clinics In Geriatric Medicine 2025, 41: 131-151. PMID: 39551538, DOI: 10.1016/j.cger.2024.03.011.Peer-Reviewed Original ResearchConceptsPain managementOlder adult populationOlder adult patientsOlder adultsAdult populationMultiple medicationsLife expectancyClinical practiceAdult patientsMedical managementPreexisting comorbiditiesPainUnited StatesDegenerative processPracticeNonagenariansMedicationAdultsComorbiditiesReviewManagementOctogenariansPatients
2024
Cognitive screening in the emergency department: Agreement between the patient‐ and caregiver‐completed AD8
Galske J, Sather A, Chera T, Hwang U, Carpenter C, Gettel C. Cognitive screening in the emergency department: Agreement between the patient‐ and caregiver‐completed AD8. Alzheimer's & Dementia 2024, 20: e087105. PMCID: PMC11710470, DOI: 10.1002/alz.087105.Peer-Reviewed Original ResearchAscertain Dementia 8Intraclass correlation coefficientEmergency departmentOlder adultsCognitive impairmentCommunity-dwelling older adultsSelf-administered screening toolElectronic health recordsTrained research assistantsDiagnosis of dementiaChanges associated with dementiaOlder adult patientsAbsence of cognitive impairmentDementia diagnosisEmergency careED settingHealth recordsCognitive screeningCaregiversAnalytic sampleResearch assistantsScreening toolDementiaModerate agreementImpaired cognitionEAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults
Keller D, Curtis N, Burt H, Ammirati C, Collings A, Polk H, Carrano F, Antoniou S, Hanna N, Piotet L, Hill S, Cuijpers A, Tejedor P, Milone M, Andriopoulou E, Kontovounisios C, Leeds I, Awad Z, Barber M, Al-Mansour M, Nassif G, West M, Pryor A, Carli F, Demartines N, Bouvy N, Passera R, Arezzo A, Francis N. EAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults. Surgical Endoscopy 2024, 38: 4104-4126. PMID: 38942944, PMCID: PMC11289045, DOI: 10.1007/s00464-024-10977-7.Peer-Reviewed Original ResearchEvidence-based recommendationsMinimally invasive surgeryOlder adultsOlder adult patientsAbdominal surgeryColorectal surgeryPerioperative carePerioperative care of older adultsAdult patientsCare of older adultsCorrection of anemiaOptimization of perioperative careInfluence surgical outcomesCertainty of evidenceCessation of smokingEvidence synthesisExpert opinionEvidence gapsSurgical outcomesPoor outcomeFunctional capacityERAS programOlder patientsPrehabilitationMeta-analysesEnhancing Brain Health and Well-Being in Older Adults: Innovations in Lifestyle Interventions
Beyer J, Dix E, Husain-Krautter S, Kyomen H. Enhancing Brain Health and Well-Being in Older Adults: Innovations in Lifestyle Interventions. Current Psychiatry Reports 2024, 26: 405-412. PMID: 38842654, DOI: 10.1007/s11920-024-01513-4.Peer-Reviewed Original ResearchOlder adult patientsBrain healthAssociated with better cognitive healthOlder adultsCognitive behavioral therapyEvidence-based treatmentsImprove cognitive functionBehavioral therapyHealthy sleep patternCognitive functionPhysical activityCognitive healthReduce anxietyLifestyle interventionMIND dietRecent FindingsEvidenceSleep hygieneLifestyle changesCognitive activityOptimal careAdult patientsSleep patternsMindfulnessWell-beingHealthQuality of Life in Older Adults With Stable Ischemic Heart Disease and Diabetes Mellitus: A Post Hoc Analysis of the BARI 2D Trial
Park D, Jamil Y, Moumneh M, Batchelor B W, Nanna M, Damluji A. Quality of Life in Older Adults With Stable Ischemic Heart Disease and Diabetes Mellitus: A Post Hoc Analysis of the BARI 2D Trial. The American Journal Of Cardiology 2024, 223: 58-69. PMID: 38797195, PMCID: PMC11214881, DOI: 10.1016/j.amjcard.2024.05.016.Peer-Reviewed Original ResearchDuke Activity Status IndexOlder adultsYears of follow-upStable ischemic heart diseaseIntensive medical therapyQoL measuresStatus indexIschemic heart diseaseDistress ratingsOlder adult populationOlder adult patientsBARI 2D trialDiabetes mellitusQuality of lifeQuality-of-lifeHeart diseaseMultivariate linear regressionFollow-upMedical therapyAdult populationQoLCognitive impairmentOlder patientsPost hoc analysisChronic total occlusionBrain Health and Well-Being in Older Adults: Innovations in Lifestyle Interventions
Kyomen H, Husain-Krautter S, Beyer J, Dix E. Brain Health and Well-Being in Older Adults: Innovations in Lifestyle Interventions. American Journal Of Geriatric Psychiatry 2024, 32: s24-s25. DOI: 10.1016/j.jagp.2024.01.082.Peer-Reviewed Original ResearchOlder adult patientsBrain healthWell-beingHealth and Well-BeingOlder adultsLifestyle changesEvidence-based guidanceCognitive exercisesBenefit of older adultsAdult patientsLifestyle interventionBrainLimitations of current dataLifestyleHealthAdultsCliniciansMindfulnessPatientsExerciseSessionsSleepCurrent dataInterventionNutritionReducing Care Overuse in Older Patients Using Professional Norms and Accountability : A Cluster Randomized Controlled Trial.
Persell S, Petito L, Lee J, Meeker D, Doctor J, Goldstein N, Fox C, Rowe T, Linder J, Chmiel R, Peprah Y, Brown T. Reducing Care Overuse in Older Patients Using Professional Norms and Accountability : A Cluster Randomized Controlled Trial. Annals Of Internal Medicine 2024, 177: 324-334. PMID: 38315997, DOI: 10.7326/m23-2183.Peer-Reviewed Original ResearchCase-based educationHealth systemOlder primary care patientsCluster randomized controlled trialPrimary care internal medicineClinical decision support toolRates of uncontrolled diabetesClinician decision supportPrimary care patientsPrimary care cliniciansProstate-specific antigenOvertreatment of diabetesNational Institute on AgingMonths of interventionDecision supportRates of PSA testingHemoglobin A<sub>1c</sub>Older adult patientsInstitute on AgingSingle Health SystemUrine testsPSA testingRandomized controlled trialsCare cliniciansEmergency care
2023
Representativeness of Peripheral Artery Disease Randomized Clinical Trials Supporting Current Guidelines
Castro-Dominguez Y, Mena-Hurtado C, Algara M, Obas V, Ahmed Z, Romain G, Solaru K, Smolderen K. Representativeness of Peripheral Artery Disease Randomized Clinical Trials Supporting Current Guidelines. The American Journal Of Cardiology 2023, 201: 166-169. PMID: 37385170, DOI: 10.1016/j.amjcard.2023.05.053.Peer-Reviewed Original ResearchConceptsPeripheral artery diseasePAD guidelinesArtery diseaseRecent American Heart Association/American CollegeAmerican Heart Association/American CollegeLower extremity peripheral artery diseaseOlder adult patientsRace/ethnicity distributionAdult patientsPooled proportionMean ageClinical trialsCurrent guidelinesEpidemiologic studiesAmerican CollegeTrial participantsRCTsEthnicity distributionOlder adultsTrialsWomenPatientsDiseaseGuidelinesEthnic groupsThe genomic landscape of adolescent and young adult (AYA) malignancies using DNA and RNA-based next generation sequencing.
Lustberg M, Kaneva K, Teslow E, Mauer E, Federman N, Eisfeld A. The genomic landscape of adolescent and young adult (AYA) malignancies using DNA and RNA-based next generation sequencing. Journal Of Clinical Oncology 2023, 41: e15091-e15091. DOI: 10.1200/jco.2023.41.16_suppl.e15091.Peer-Reviewed Original ResearchTriple-negative breast cancerTumor mutational burdenCancer patientsAYA patientsMicrosatellite instabilityBreast cancerNext-generation sequencingYoung adult cancer patientsYoung adult malignancyColorectal cancer patientsAdult cancer patientsHER2- breast cancerOlder adult patientsAYA cancer patientsSoft tissue sarcomasCentral nervous systemHigh-grade gliomasLow-grade gliomasPathogenic single nucleotide variantsAYA cancerSingle nucleotide variantsAdult patientsGastrointestinal malignanciesNTRK fusionsAML subgroupsLifestyle Interventions for Brain Health and Well-Being
Kyomen H, Husain-Krautter S, Beyer J, Dix E. Lifestyle Interventions for Brain Health and Well-Being. American Journal Of Geriatric Psychiatry 2023, 31: s21. DOI: 10.1016/j.jagp.2022.12.306.Peer-Reviewed Original ResearchCutaneous leishmaniasis treatment and therapeutic outcomes in special populations: A collaborative retrospective study
del Mar Castro M, Rode J, Machado P, Llanos-Cuentas A, Hueb M, Cota G, Rojas I, Orobio Y, Sarmiento O, Rojas E, Quintero J, Pimentel M, Soto J, Suprien C, Alvarez F, Ramos A, dos Santos Arantes R, da Silva R, Arenas C, Vélez I, Lyra M, Saravia N, Arana B, Alexander N. Cutaneous leishmaniasis treatment and therapeutic outcomes in special populations: A collaborative retrospective study. PLOS Neglected Tropical Diseases 2023, 17: e0011029. PMID: 36689465, PMCID: PMC9894540, DOI: 10.1371/journal.pntd.0011029.Peer-Reviewed Original ResearchConceptsCollaborative retrospective studyRetrospective studyAdverse reactionsCutaneous leishmaniasisAge groupsMedian lesion diameterOverall cure rateOlder adult patientsMost adverse reactionsCutaneous leishmaniasis treatmentYears of ageMonotherapy regimenAdult patientsReferral centerLocal therapyPediatric populationClinical recordsCure rateCL patientsTherapeutic responseClinical trialsDisease presentationMedian numberMild intensityAntileishmanial treatment
2022
In-hospital outcomes and readmission in older adults treated with percutaneous coronary intervention for stable ischemic heart disease
Park DY, Hanna JM, Kadian S, Kadian M, Jones WS, Damluji AA, Kochar A, Curtis JP, Nanna MG. In-hospital outcomes and readmission in older adults treated with percutaneous coronary intervention for stable ischemic heart disease. Journal Of Geriatric Cardiology 2022, 19: 631-642. PMID: 36284680, PMCID: PMC9548058, DOI: 10.11909/j.issn.1671-5411.2022.09.006.Peer-Reviewed Original ResearchStable ischemic heart diseasePercutaneous coronary interventionInpatient percutaneous coronary interventionIschemic heart diseaseHospital mortalityOlder adultsIndex hospitalizationCoronary interventionHospital chargesHeart diseaseNational Readmission DatabaseTotal hospital chargesHigh-risk cohortOlder adult patientsPeriprocedural morbidityCardiovascular causesGastrointestinal hemorrhageHospital lengthHospital outcomesAdult patientsSecondary outcomesLonger LOSPrimary outcomeIntracranial hemorrhageProcedural riskSurrogate consent for surgery among older adult patients
Miller SM, Nagarkatti N, Ahuja V, Schneider EB, Mohanty S, Rosenthal RA, Kodadek LM. Surrogate consent for surgery among older adult patients. Surgery 2022, 172: 1748-1752. PMID: 36123180, DOI: 10.1016/j.surg.2022.08.015.Peer-Reviewed Original ResearchConceptsHalf of patientsCognitive impairmentSurrogate consentHigher comorbidity burdenOlder adult patientsComorbidity burdenPreoperative disabilityAdult patientsOlder patientsFemale patientsSurgical interventionElective proceduresSurgical proceduresHealth characteristicsAmerican CollegeDaily livingOwn consentPatientsOlder adultsImpairmentSurgeryConsentDescriptive analysisFurther researchDiagnosisA Qualitative Study of “What Matters” to Older Adults in the Emergency Department
Gettel CJ, Venkatesh AK, Dowd H, Hwang U, Ferrigno RF, Reid EA, Tinetti ME. A Qualitative Study of “What Matters” to Older Adults in the Emergency Department. Western Journal Of Emergency Medicine 2022, 23: 579-588. PMID: 35980413, PMCID: PMC9391017, DOI: 10.5811/westjem.2022.4.56115.Peer-Reviewed Original ResearchConceptsOlder adult patientsAdult patientsEmergency departmentOlder adultsED careAge-Friendly Health SystemIntact older adultsSymptom resolutionED cliniciansED settingPatient 1Clinician recommendationsPatient concernsPatient prioritiesDyadic semi-structured interviewsSymptom reductionClinical practicePatientsCliniciansHealth systemConversation guideHealthcare systemAdultsHome environmentOutcomes
2021
Predictors of Major Atrial Fibrillation Endpoints in the National Heart, Lung, and Blood Institute HCMR
Kramer CM, DiMarco JP, Kolm P, Ho CY, Desai MY, Kwong RY, Dolman SF, Desvigne-Nickens P, Geller N, Kim DY, Maron MS, Appelbaum E, Jerosch-Herold M, Friedrich MG, Schulz-Menger J, Piechnik SK, Mahmod M, Jacoby D, White J, Chiribiri A, Helms A, Choudhury L, Michels M, Bradlow W, Salerno M, Dawson DK, Weinsaft JW, Berry C, Nagueh SF, Buccarelli-Ducci C, Owens A, Casadei B, Watkins H, Weintraub WS, Neubauer S, Investigators H. Predictors of Major Atrial Fibrillation Endpoints in the National Heart, Lung, and Blood Institute HCMR. JACC Clinical Electrophysiology 2021, 7: 1376-1386. PMID: 34217663, PMCID: PMC8605982, DOI: 10.1016/j.jacep.2021.04.004.Peer-Reviewed Original ResearchConceptsBody mass indexSevere mitral regurgitationHistory of arrhythmiaMitral regurgitationHypertrophic cardiomyopathyAtrial fibrillationLA volumeProspective natural history studyVolume indexHigher body mass indexAtrial volume indexLA volume indexPermanent atrial fibrillationOlder adult patientsStrong risk factorNatural history studiesCommon morbidityAdult patientsElectrical cardioversionYounger patientsCatheter ablationEndpoint eventsMass indexNational HeartRisk factorsED‐DEL: Development of a change package and toolkit for delirium in the emergency department
Kennedy M, Webb M, Gartaganis S, Hwang U, Biese K, Stuck A, Lesser A, Hshieh T, Inouye SK. ED‐DEL: Development of a change package and toolkit for delirium in the emergency department. Journal Of The American College Of Emergency Physicians Open 2021, 2: e12421. PMID: 33969341, PMCID: PMC8082702, DOI: 10.1002/emp2.12421.Peer-Reviewed Original ResearchEmergency departmentED settingGeriatric Emergency Department GuidelinesManagement of deliriumOlder adult patientsEmergency Department GuidelinesEmergency department environmentAvailable patient informationAdult patientsChange packageInpatient unitDelirium identificationPatient acuityDeliriumDelirium programOlder populationOlder adultsDepartment guidelinesPatient crowdingPatient informationDepartment environmentDeadly problemUnique needsDepartmentMultistep process
2019
Association of atypical antipsychotics and mortality for patients hospitalised with pneumonia
Boivin Z, Perez M, Atuegwu N, Metersky M, Alvarez C, Anzueto A, Mortensen E. Association of atypical antipsychotics and mortality for patients hospitalised with pneumonia. ERJ Open Research 2019, 5: 00223-2018. PMID: 31720299, PMCID: PMC6826252, DOI: 10.1183/23120541.00223-2018.Peer-Reviewed Original ResearchAtypical antipsychotic useAntipsychotic useAtypical antipsychoticsPatients 65Retrospective cohort studyOdds of mortalityOlder adult patientsAtypical antipsychotic usersAdult patientsCohort studyAntipsychotic usersSafety dataCardiac conditionsPneumoniaPatientsPrimary analysisPsychiatric conditionsAntipsychoticsMortalityNonusersOddsAssociationMedicationsAdmissionConfounders
2017
Care of the Geriatric Surgery Patient: The Surgeon’s Perspective
Hornor M, McDonald J, Anaya D, Rosenthal R. Care of the Geriatric Surgery Patient: The Surgeon’s Perspective. 2017, 85-97. DOI: 10.1007/978-3-319-66878-9_7.ChaptersGeriatric surgical patientsSurgical patientsHigh-quality surgical careHealthcare goalsGeriatric surgery patientsOlder adult patientsRisk of complicationsInterdisciplinary teamAdult patientsAnalgesic planDevastating complicationSurgery patientsEarly mobilizationPerioperative phaseGeriatric patientsGeriatric physiciansOptimal carePatient goalsPredictable complicationsFunctional declineSurgical careHigh riskPatientsPatient engagementPhysical therapistsEffects of depression screening on diagnosing and treating mood disorders among older adults in office-based primary care outpatient settings: An instrumental variable analysis
Rhee TG, Capistrant BD, Schommer JC, Hadsall RS, Uden DL. Effects of depression screening on diagnosing and treating mood disorders among older adults in office-based primary care outpatient settings: An instrumental variable analysis. Preventive Medicine 2017, 100: 101-111. PMID: 28414065, DOI: 10.1016/j.ypmed.2017.04.015.Peer-Reviewed Original ResearchConceptsNational Ambulatory Medical Care SurveyEffect of depressionAntidepressant prescriptionsDepression screeningOlder adultsMood disordersCross-sectional population-based studyOutpatient primary care settingPrimary care outpatient settingPrimary care outpatient visitsAmbulatory Medical Care SurveyPrimary care visitsOlder adult patientsPopulation-based studyPrimary care physiciansPrimary care settingOlder adults age 65Mood disorder diagnosisOutcomes of interestAdults age 65Effectiveness of depressionAdult patientsCare visitsCare physiciansOutpatient visitsSystematic Review of Hospital Readmissions Among Patients With Cancer in the United States.
Bell J, Whitney R, Reed S, Poghosyan H, Lash R, Kim K, Davis A, Bold R, Joseph J. Systematic Review of Hospital Readmissions Among Patients With Cancer in the United States. Oncology Nursing Forum 2017, 44: 176-191. PMID: 28222076, DOI: 10.1011/17.onf.176-191.Peer-Reviewed Original ResearchConceptsReadmission ratesImplement evidence-based interventionsNational Cancer Institute's Surveillance EpidemiologyCare coordination interventionEvidence-based interventionsOlder adult patientsOncology nursesNursing interventionsOncology settingReadmission preventionSignificant predictors of readmissionCoordinated interventionsDatabases-PubMedHospital readmissionPredictors of readmissionManagement of nauseaSurveillance EpidemiologySystematic reviewInclusion criteriaAdvanced cancerInfection preventionLength of hospital stayReadmissionOlder ageComorbid conditions
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