2025
The Challenging Problems of Cancer and Serious Mental Illness
Grassi L, McFarland D, Riba M, Ferrara M, Zaffarami G, Belvederi Murri M, Cruciata M, Caruso R. The Challenging Problems of Cancer and Serious Mental Illness. Current Psychiatry Reports 2025, 27: 41-57. PMID: 39786658, PMCID: PMC11724792, DOI: 10.1007/s11920-024-01570-9.Peer-Reviewed Original ResearchConceptsSerious mental illnessProblem of cancerMental illnessGeneral populationPhysical health careRates of screeningMental health servicesHealth-care systemMedication side effectsHealth servicesOncology settingUnhealthy lifestyleHealth careCancer preventionStandard cancer treatmentHigher mortalitySomatic disordersCareVulnerable segmentsNegative outcomesIllnessOncologyCancer treatmentDelayed treatmentCancer
2024
Immunogenicity of cell death and cancer immunotherapy with immune checkpoint inhibitors
Catanzaro E, Beltrán-Visiedo M, Galluzzi L, Krysko D. Immunogenicity of cell death and cancer immunotherapy with immune checkpoint inhibitors. Cellular & Molecular Immunology 2024, 22: 24-39. PMID: 39653769, PMCID: PMC11685666, DOI: 10.1038/s41423-024-01245-8.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsImmunogenic cell deathImmunogenic cell death inducerCheckpoint inhibitorsRefractory to immune checkpoint inhibitorsImmunogenicity of cell deathFraction of patientsCombinatorial treatment strategiesAdaptive immune responsesCell deathCombinatorial partnersCancer immunotherapyCombinatorial regimensClinical findingsClinical managementTreatment strategiesClinical activityImmune responseImmunotherapyPatientsCancerOncology settingInhibitorsDeathInducerBridging clinical informatics and implementation science to improve cancer symptom management in ambulatory oncology practices: experiences from the IMPACT consortium
McCleary N, Merle J, Richardson J, Bass M, Garcia S, Cheville A, Mitchell S, Jensen R, Minteer S, Austin J, Tesch N, DiMartino L, Hassett M, Osarogiagbon R, Wong S, Schrag D, Cella D, Smith A, Smith J, Cella D, Cheville A, Hassett M, Osarogiagbon R, Schrag D, Wong S, Kroner B, Smith A, DiMartino L, Garcia S, Griffin J, Jensen R, Mitchell S, Ruddy K, Smith J, Yanez B, Bian J, Dizon D, Hazard-Jenkins H, Ardini M, Ahrens P, Austin J, Barrett F, Bass M, Begnoche M, Cahue S, Caron K, Chlan L, Coughlin A, Cronin C, Dias S, Faris N, Flores A, Garcia M, Hemming K, Herrin J, Hodgdon C, Kircher S, Kroenke K, Lam V, Lancki N, H Q, Mallow J, McCleary N, Norton W, O'Connor M, Pachman D, Pearson L, Penedo F, Podratz J, Popovic J, Preiss L, Rahman P, Redmond S, Reich J, Richardson J, Richardson K, Ridgeway J, Rutten L, Schaepe K, Scholtens D, Poirier-Shelton T, Silberman P, Simpson J, Tasker L, Tesch N, Tofthagen C, Tramontano A, Tyndall B, Uno H, Wehbe F, Weiner B. Bridging clinical informatics and implementation science to improve cancer symptom management in ambulatory oncology practices: experiences from the IMPACT consortium. JAMIA Open 2024, 7: ooae081. PMID: 39234146, PMCID: PMC11373565, DOI: 10.1093/jamiaopen/ooae081.Peer-Reviewed Original ResearchElectronic patient-reported outcomesElectronic health recordsClinical informaticsImplementation scienceImplementation of electronic patient-reported outcomesElectronic health record designElectronic health record systemsImplementation strategiesCancer symptom managementSystematic symptom assessmentAmbulatory oncology settingAmbulatory oncology practicesManagement of symptomsPatient-reported outcomesEHR functionsEPRO dataCancer symptomsSymptom managementIS researchHealth recordsImplementation scientistsPragmatic trialOncology settingInformatics implementationSymptom assessmentBarriers to Clinical Trial Implementation Among Community Care Centers
Ebrahimi H, Megally S, Plotkin E, Shivakumar L, Salgia N, Zengin Z, Meza L, Chawla N, Castro D, Dizman N, Bhagat R, Liv S, Li X, Rock A, Liu S, Tripathi A, Dorff T, Oyer R, Boehmer L, Pal S, Chehrazi-Raffle A. Barriers to Clinical Trial Implementation Among Community Care Centers. JAMA Network Open 2024, 7: e248739. PMID: 38683608, PMCID: PMC11059033, DOI: 10.1001/jamanetworkopen.2024.8739.Peer-Reviewed Original ResearchConceptsClinical trial implementationClinical trial enrollmentTrial enrollmentUnmet needsCancer clinical trial enrollmentHealth care practicesPatients seeking careTrial implementationCommunity care centersCommunity oncology settingNational survey studyRural practiceClinical research opportunitiesCare practicesCare settingsCancer clinicOncology settingLimited staffingPractice changeRural settingsOncology clinicMain OutcomesHispanic residentsReferral practicesTrial participantsDevelopment and Validation of Case-Finding Algorithms to Identify Pancreatic Cancer in the Veterans Health Administration
Mezzacappa C, Larki N, Skanderson M, Park L, Brandt C, Hauser R, Justice A, Yang Y, Wang L. Development and Validation of Case-Finding Algorithms to Identify Pancreatic Cancer in the Veterans Health Administration. Digestive Diseases And Sciences 2024, 69: 1507-1513. PMID: 38453743, DOI: 10.1007/s10620-024-08324-w.Peer-Reviewed Original ResearchElectronic health recordsVeterans Health AdministrationHealth AdministrationElectronic health records data elementsElectronic health record dataDiagnosis of exocrine pancreatic cancerNational Cancer RegistryCancer RegistryHealth recordsExocrine pancreatic cancerOncology settingOutpatient encountersInpatient encountersData elementsExpert adjudicationPancreatic ductal adenocarcinomaEpidemiological studiesRandom sampleInterquartile rangeIdentification of patientsRange of patientsPancreatic cancerVeteransLate diagnosisExcellent PPV
2023
Retrospective cohort study of scalp cooling in breast cancer patients
Rose L, Schnell P, Radcliff L, Lustberg M, Dulmage B. Retrospective cohort study of scalp cooling in breast cancer patients. Supportive Care In Cancer 2023, 31: 118. PMID: 36645520, DOI: 10.1007/s00520-022-07562-w.Peer-Reviewed Original ResearchConceptsScalp coolingChemotherapy regimenPatient ageInsurance statusRetrospective cohort studyCommon side effectsRetrospective chart reviewNon-white patientsBreast cancer patientsStage of cancerQuality of lifeChart reviewCohort studyWhite patientsPatient's likelihoodChemotherapy infusionCancer patientsTreatment optionsOncology settingBreast cancerPatient decisionSide effectsPatientsTreatment planHealthcare providers
2022
Sexual and gender minority cultural humility training for oncology settings: An example of iterative adaptation and implementation
Kamen C, Reichelt M, Dadgostar P, Alpert A, Doucette C, Vaughan P, Keuroghlian A, Yousefi-Nooraie R. Sexual and gender minority cultural humility training for oncology settings: An example of iterative adaptation and implementation. Frontiers In Health Services 2022, 2: 958274. PMID: 36925900, PMCID: PMC10012625, DOI: 10.3389/frhs.2022.958274.Peer-Reviewed Original ResearchCultural humility trainingOncology practiceOncology settingOncology care settingsCancer care providersMultiple national organizationsThe Fenway InstituteImplementing such trainingInstitutional culture changeOncology providersTraining team membersReporting AdaptationsCare providersCare settingsHealth needsSGM patientsTraining interventionHealth carePractice environmentTraining sessionsOncology departmentContent of trainingTeam membersNational organizationsRadiation oncology departmentsGender- and Sexual Orientation- Based Inequities: Promoting Inclusion, Visibility, and Data Accuracy in Oncology.
Alpert A, Scout N, Schabath M, Adams S, Obedin-Maliver J, Safer J. Gender- and Sexual Orientation- Based Inequities: Promoting Inclusion, Visibility, and Data Accuracy in Oncology. American Society Of Clinical Oncology Educational Book 2022, 42: 1-17. PMID: 35658501, DOI: 10.1200/edbk_350175.Peer-Reviewed Original ResearchConceptsTransgender identityTransgender peopleGender minoritiesImpact of stigmaGender identitySexual orientationSGM peopleStructural discriminationSGM patientsSGMPromote inclusionGenderSystem changesU.S. populationOncology settingPeopleStigmaIdentityGenderqueerQueerTransgenderAgenderComprehensive data collectionCancer disparitiesInequality
2018
Association of Broad-Based Genomic Sequencing With Survival Among Patients With Advanced Non–Small Cell Lung Cancer in the Community Oncology Setting
Presley CJ, Tang D, Soulos PR, Chiang AC, Longtine JA, Adelson KB, Herbst RS, Zhu W, Nussbaum NC, Sorg RA, Agarwala V, Abernethy AP, Gross CP. Association of Broad-Based Genomic Sequencing With Survival Among Patients With Advanced Non–Small Cell Lung Cancer in the Community Oncology Setting. JAMA 2018, 320: 469-477. PMID: 30088010, PMCID: PMC6142984, DOI: 10.1001/jama.2018.9824.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnaplastic Lymphoma KinaseAntineoplastic AgentsCarcinoma, Non-Small-Cell LungDNA, NeoplasmFemaleGenes, erbB-1GenomicsGenotypeHumansImmunotherapyLung NeoplasmsMaleMiddle AgedMutationNeoplasm StagingReceptor Protein-Tyrosine KinasesRetrospective StudiesSequence Analysis, DNASurvival AnalysisConceptsAdvanced non-small cell lung cancerNon-small cell lung cancerCommunity oncology settingCell lung cancerLung cancerOncology settingRoutine testingNonsquamous non-small cell lung cancerTargeted treatmentPropensity score-matched survival analysisStage IIIB/IVFlatiron Health databaseIIIB/IVRetrospective cohort studyThird-line treatmentFirst-line treatmentMinority of patientsUnadjusted mortality ratesEGFR/ALKCohort studyOverall survivalSecondary outcomesUnmatched cohortPrimary outcomeAntineoplastic treatment
2017
Systematic Review of Hospital Readmissions Among Patients With Cancer in the United States.
Bell J, Whitney R, Reed S, Poghosyan H, Lash R, Kim K, Davis A, Bold R, Joseph J. Systematic Review of Hospital Readmissions Among Patients With Cancer in the United States. Oncology Nursing Forum 2017, 44: 176-191. PMID: 28222076, DOI: 10.1011/17.onf.176-191.Peer-Reviewed Original ResearchConceptsReadmission ratesImplement evidence-based interventionsNational Cancer Institute's Surveillance EpidemiologyCare coordination interventionEvidence-based interventionsOlder adult patientsOncology nursesNursing interventionsOncology settingReadmission preventionSignificant predictors of readmissionCoordinated interventionsDatabases-PubMedHospital readmissionPredictors of readmissionManagement of nauseaSurveillance EpidemiologySystematic reviewInclusion criteriaAdvanced cancerInfection preventionLength of hospital stayReadmissionOlder ageComorbid conditions
2013
Assessing Tobacco Use by Cancer Patients and Facilitating Cessation: An American Association for Cancer Research Policy Statement
Toll BA, Brandon TH, Gritz ER, Warren GW, Herbst RS, Tobacco and Cancer W. Assessing Tobacco Use by Cancer Patients and Facilitating Cessation: An American Association for Cancer Research Policy Statement. Clinical Cancer Research 2013, 19: 1941-1948. PMID: 23570694, PMCID: PMC5992896, DOI: 10.1158/1078-0432.ccr-13-0666.Peer-Reviewed Original ResearchConceptsTobacco useTobacco cessationCessation interventionsEvidence-based cessation interventionsTreatment-related toxicitySecond primary tumorsTobacco cessation interventionsQuality cancer careQuality of lifeAmerican AssociationCessation assistancePoor outcomeCancer careCancer patientsPrimary tumorOncology settingCancer recurrencePatientsTreatment efficacyTreatment settingsEvidence-based proceduresCancer leadCancerCancer progressionClinical infrastructure
2008
NCCN Task Force Report: breast cancer in the older woman.
Carlson RW, Moench S, Hurria A, Balducci L, Burstein HJ, Goldstein LJ, Gradishar WJ, Hughes KS, Jahanzeb M, Lichtman SM, Marks LB, McClure JS, McCormick B, Nabell LM, Pierce LJ, Smith ML, Topham NS, Traina TA, Ward JH, Winer EP. NCCN Task Force Report: breast cancer in the older woman. Journal Of The National Comprehensive Cancer Network 2008, 6 Suppl 4: s1-25; quiz s26-7. PMID: 18597715, DOI: 10.6004/jnccn.2008.2004.Peer-Reviewed Original ResearchConceptsBreast cancerOlder patientsOlder womenBreast cancer treatment recommendationsCancer treatment recommendationsSurgical axillary stagingGeriatric assessment toolsPresence of comorbiditiesMetastatic breast cancerBreast cancer patientsRandomized clinical trialsCurative surgeryNCCN institutionsAxillary stagingEndocrine therapyGeriatric oncologySupportive therapyTask ForceMedical oncologyCancer patientsFunctional statusOncology settingTreatment recommendationsClinical trialsMultidisciplinary panel
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