2025
Comments on: Bariatric surgery targeting opioid prescribing: a national model for effectively reducing opioid use after bariatric surgery
Ying L, Ghiassi S. Comments on: Bariatric surgery targeting opioid prescribing: a national model for effectively reducing opioid use after bariatric surgery. Surgery For Obesity And Related Diseases 2025, 21: 410-411. PMID: 39864987, DOI: 10.1016/j.soard.2024.12.021.Peer-Reviewed Original Research
2024
Bariatric surgery targeting opioid prescribing: a national model for effectively reducing opioid use after bariatric surgery
Petrick A, Shah T, Gadaleta D, Gould J, Morton J, Smith A, Evans-Labok K, Knapp L, Ko C, Brethauer S. Bariatric surgery targeting opioid prescribing: a national model for effectively reducing opioid use after bariatric surgery. Surgery For Obesity And Related Diseases 2024, 21: 402-410. PMID: 39753417, DOI: 10.1016/j.soard.2024.11.011.Peer-Reviewed Original ResearchMedian morphine milligram equivalentsOpioid useBariatric surgeryOpioid prescriptionsOpioid prescribingPrescription opioidsMBSAQIP-accredited centersOpioid naive patientsOutpatient opioid useChronic opioid usersChronic opioid useInpatient opioid useMorphine milligram equivalentsBariatric Surgery AccreditationReduce opioid prescribingOpioid-related deathsMilligram equivalentsOpioid usersPrescription habitsOpioidSurgeryProtocol adherenceInpatient stayPrescription guidelinesBariatricThe Circumstances Surrounding Fatal Pediatric Opioid Poisonings, 2004-2020.
Gaither J, McCollum S, Bechtel K, Leventhal J, Mintz S. The Circumstances Surrounding Fatal Pediatric Opioid Poisonings, 2004-2020. Pediatrics 2024, 154 PMID: 39484873, PMCID: PMC11528886, DOI: 10.1542/peds.2024-067043n.Peer-Reviewed Original ResearchConceptsChild's own homeOpioid poisoningOwn homeHistory of maltreatmentSubstance use/abuseAge groupsDied of homicidePrimary caregiversYears of ageOpioid prescribingChildren 0Opioid fatalitiesHousehold factorsPrescription opioidsSubstance useChild maltreatmentCaregiversDecedentsReporting SystemIllicit fentanylMaltreatmentChildrenFatal opioid poisoningsAgeHomeRacial Disparities in Opioid Prescribing in the United States from 2011 to 2021: A Systematic Review and Meta-Analysis
Hirani S, Benkli B, Odonkor C, Hirani Z, Oso T, Bohacek S, Wiedrick J, Hildebrand A, Osuagwu U, Orhurhu V, Hooten W, Abdi S, Meghani S. Racial Disparities in Opioid Prescribing in the United States from 2011 to 2021: A Systematic Review and Meta-Analysis. Journal Of Pain Research 2024, 17: 3639-3649. PMID: 39529944, PMCID: PMC11552391, DOI: 10.2147/jpr.s477128.Peer-Reviewed Original ResearchNon-Hispanic white patientsOpioid analgesiaRacial/ethnic disparitiesWhite patientsMeta-analysisPain managementHispanic patientsSystematic reviewPain treatmentBlack patientsUnited StatesPersistent disparitiesAdult patient populationPrescription medicationsPain outcomesRacial disparitiesOpioid prescribingHispanic populationAnalgesic outcomesOpioid analgesicsSystematic searchPatient populationAnalgesiaPainDisparitiesStrategies to Deimplement Opioid Prescribing in Primary Care
Quanbeck A, Robinson J, Jacobson N, Li X, Hennessy-Garza R, Landeck J, Cohen A, Madden L, Pulvermacher A, Brown R. Strategies to Deimplement Opioid Prescribing in Primary Care. JAMA Network Open 2024, 7: e2438325. PMID: 39388183, PMCID: PMC11581553, DOI: 10.1001/jamanetworkopen.2024.38325.Peer-Reviewed Original ResearchConceptsCluster randomized clinical trialDeimplementation strategiesMorphine milligram equivalent doseMorphine milligram equivalentsPractice facilitationOpioid prescribingIncreased screeningTreatment agreementsUS health care systemCenters for Disease Control and Prevention guidelinesRandomized clinical trialsUrine drug screensPrimary care clinicsPrimary care settingPrimary outcomeMental health screeningPain-related interferenceHealth care systemHigh-intensity groupEnjoyment of lifeChronic pain managementPrimary careCare clinicsCare settingsHealth screeningUse of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees
Bongiovanni T, Gan S, Finlayson E, Ross J, Harrison J, Boscardin J, Steinman M. Use of Muscle Relaxants After Surgery in Traditional Medicare Part D Enrollees. Drugs & Aging 2024, 41: 615-622. PMID: 38980644, PMCID: PMC11249446, DOI: 10.1007/s40266-024-01124-x.Peer-Reviewed Original ResearchConceptsMuscle relaxant prescriptionsOlder adultsSpine proceduresPain controlMuscle relaxationRisk of prolonged useProlonged useMedication-related problemsDecreased opioid useRates of prescribingMuscle relaxant useResultsThe study cohortPostoperative pain managementPrescribed to patientsYears of agePostoperative prescribingStudy DesignUsingNonopioid medicationsOpioid useOpioid prescribingMedicare Part DPostoperative periodMedicare Part D enrolleesRetrospective analysisPain managementHow Should the Use of Opioids Be Regulated to Motivate Better Clinical Practice?
Edens E, Garcia Vassallo G, Heimer R. How Should the Use of Opioids Be Regulated to Motivate Better Clinical Practice? The AMA Journal Of Ethic 2024, 26: e551-561. PMID: 38958424, DOI: 10.1001/amajethics.2024.551.Peer-Reviewed Original ResearchConceptsTreat opioid use disorderOpioid use disorderPrescribed long-term opioid therapyLong-term opioid therapyOpioid prescribing policiesOpioid therapyPrescribed opioidsOpioid prescribingUse disorderOpioidClinical practicePainPrescribing policiesDiagnostic categoriesClinical frameworkPrescribingPolitical reasonsTherapyOpioid prescribing trends and pain scores among adult patients with cancer in a large health system.
Baum L, Soulos P, KC M, Jeffery M, Ruddy K, Lerro C, Lee H, Graham D, Liberatore M, Rivera D, Leapman M, Jairam V, Dinan M, Gross C, Park H. Opioid prescribing trends and pain scores among adult patients with cancer in a large health system. Journal Of Clinical Oncology 2024, 42: 11059-11059. DOI: 10.1200/jco.2024.42.16_suppl.11059.Peer-Reviewed Original ResearchDocumented painHealth systemOpioid prescribingOpioid prescriptionsOpioid prescribing trendsYale New Haven Health SystemPrescribing trendsMetastatic cancerDocumented pain scoresUS health systemOpioid usePain scoresAdult patientsCalculated predicted probabilitiesFlowsheet dataRetrospective cohort studyRelated harmSolid tumor malignanciesCohort studyCancer painPrescribingContext of cancer treatmentStudy criteriaPainSurgery cohortDrivers of Variation in Opioid Prescribing after Common Surgical Procedures in a Large Multihospital Healthcare System
Zanocco K, Romanelli R, Meeker D, Mariano L, Shenoy R, Wagner Z, Kirkegaard A, Mudiganti S, Martinez M, Watkins K. Drivers of Variation in Opioid Prescribing after Common Surgical Procedures in a Large Multihospital Healthcare System. Journal Of The American College Of Surgeons 2024, 239: 242-252. PMID: 38690834, PMCID: PMC11321601, DOI: 10.1097/xcs.0000000000001095.Peer-Reviewed Original ResearchElectronic health recordsMultihospital healthcare systemOpioid prescribingHealthcare systemNon-Hispanic black raceMorphine milligram equivalentsPrimary care providersReducing postoperative opioid prescribingOpioid prescribing practicesInfluence pain levelsRandom-effects modelCare providersPatient safetyHealth recordsProvider levelInsurance statusMisuse of prescription opioidsPostoperative opioid prescribingPatient racePrescribing behaviorPrescribing variationGuideline recommendationsPrescribing practicesTargeted prescribingMedicare insuranceAlcohol-Related Care Among Veterans With Unhealthy Alcohol Use: The Role of Long-Term Opioid Therapy Receipt
Joudrey P, Wang M, DeRycke E, Williams E, Edelman E. Alcohol-Related Care Among Veterans With Unhealthy Alcohol Use: The Role of Long-Term Opioid Therapy Receipt. Journal Of Addiction Medicine 2024, 18: 293-299. PMID: 38533996, PMCID: PMC11150097, DOI: 10.1097/adm.0000000000001291.Peer-Reviewed Original ResearchUnhealthy alcohol useAlcohol-related careLong-term opioid therapyBrief interventionOpioid receiptAlcohol useReceipt of alcohol-related careReceipt of brief interventionVeterans Health Administration careRates of brief interventionDocumented brief interventionNational cohort of veteransWomen Veterans Cohort StudyCohort of veteransPositive alcohol screensAlcohol screeningIntervention receiptAdministration carePositive screenConsumption questionnaireOpioid prescribingNational cohortTherapy receiptCohort studyCareIdentifying provider, patient and practice factors that shape long-term opioid prescribing for cancer pain: a qualitative study of American and Australian providers
Fereydooni S, Lorenz K, Azarfar A, Luckett T, Phillips J, Becker W, Giannitrapani K. Identifying provider, patient and practice factors that shape long-term opioid prescribing for cancer pain: a qualitative study of American and Australian providers. BMJ Open 2024, 14: e082033. PMID: 38514141, PMCID: PMC10961503, DOI: 10.1136/bmjopen-2023-082033.Peer-Reviewed Original ResearchConceptsPractice-related factorsLong-term opioid prescribingPrescribed long-term opioid therapyQualitative studyOpioid prescribingQuality of careProvider-related factorsLong-term prescribingPatient’s social contextLong-term opioid therapyAlternative pain therapiesCancer-related painConcurrent qualitative studyDisadvantaged patientsHealthcare interventionsExacerbate disparitiesIdentified providersAustralian providersOpioid practicesSocioeconomic statusSecondary analysisPrescribed opioidsCancer painProvidersPrescribingPost-Traumatic Stress Disorder Is Associated With Increased Emergency Department Services and Similar Rates of Opioid Prescriptions Following Primary Total Hip Arthroplasty: A Propensity Matched Analysis
Monahan P, Martinazzi B, Pahapill N, Graefe S, Jimenez A, Mason M. Post-Traumatic Stress Disorder Is Associated With Increased Emergency Department Services and Similar Rates of Opioid Prescriptions Following Primary Total Hip Arthroplasty: A Propensity Matched Analysis. The Journal Of Arthroplasty 2024, 39: s287-s292.e1. PMID: 38492824, DOI: 10.1016/j.arth.2024.03.012.Peer-Reviewed Original ResearchPost-traumatic stress disorderPost-traumatic stress disorder patientsHealth care utilizationStress disorderPrimary total hip arthroplastyRate of postoperative complicationsCare utilizationTotal hip arthroplastyRate of opioid prescriptionsPrescribed opioid analgesicsPropensity matched analysisRates of health care utilizationSimilarity ratingsEmergency department servicesEmergency department visitsHip arthroplastyPreoperative characteristicsPostoperative prescriptionOpioid analgesicsPostoperative complicationsOpioid prescriptionsOpioid prescribingPsychiatric diagnosisPeer Comparison or Guideline-Based Feedback and Postsurgery Opioid Prescriptions
Wagner Z, Kirkegaard A, Mariano L, Doctor J, Yan X, Persell S, Goldstein N, Fox C, Brummett C, Romanelli R, Bouskill K, Martinez M, Zanocco K, Meeker D, Mudiganti S, Waljee J, Watkins K. Peer Comparison or Guideline-Based Feedback and Postsurgery Opioid Prescriptions. JAMA Health Forum 2024, 5: e240077. PMID: 38488780, PMCID: PMC10943416, DOI: 10.1001/jamahealthforum.2024.0077.Peer-Reviewed Original ResearchConceptsCluster randomized clinical trialPeer comparison interventionOpioid prescribingEmail feedbackGuideline interventionComparison interventionIntervention periodHealth care delivery systemRandomized clinical trialsOpioid prescriptionsCare delivery systemPeer comparisonExcessive opioid prescribingSocial norm-based interventionsControl groupIntervention monthsMain OutcomesQuantity of opioidsClinical trialsDischarged patientsPeer surgeonsPrescribingOpioid misuseInterventionSurgical specialties
2023
Paths Forward for Clinicians Amidst the Rise of Unregulated Clinical Decision Support Software: Our Perspective on NarxCare
Buonora M, Axson S, Cohen S, Becker W. Paths Forward for Clinicians Amidst the Rise of Unregulated Clinical Decision Support Software: Our Perspective on NarxCare. Journal Of General Internal Medicine 2023, 39: 858-862. PMID: 37962733, PMCID: PMC11043299, DOI: 10.1007/s11606-023-08528-2.Peer-Reviewed Original ResearchClinical decision support toolClinical decision support softwareHealthcare institutionsOpioid prescribingOverdose epidemicPatient encountersIndividual cliniciansPatient careProprietary formulaRigorous external validationCliniciansWider implementationExternal validationPrescribingPotential harmSufficient evidencePublic healthDecision support softwareDecision support toolSpecific actionsMortalityCareTrends in new and persistent opioid use in older adults with and without cancer
Baum L, KC M, Soulos P, Jeffery M, Ruddy K, Lerro C, Lee H, Graham D, Rivera D, Leapman M, Jairam V, Dinan M, Gross C, Park H. Trends in new and persistent opioid use in older adults with and without cancer. Journal Of The National Cancer Institute 2023, 116: 316-323. PMID: 37802882, DOI: 10.1093/jnci/djad206.Peer-Reviewed Original ResearchAdditional opioid useNew opioid useOpioid useNon-metastatic cancerPersistent opioid useRetrospective cohort studySolid tumor malignanciesClinical strataEligible patientsNaïve patientsOpioid prescribingMetastatic patientsSurgery patientsCohort studySEER-MedicareMetastatic cancerPatientsTumor malignancyCancerOlder adultsSurgeryRandom sampleAdditional useChemotherapyPrescribingChanges in opioid prescribing in veterans with headache during the COVID‐19 pandemic: A regression discontinuity in time analysis
Wang K, Fenton B, Skanderson M, Black A, Becker W, Seng E, Anthony S, Guirguis A, Altalib H, Kimber A, Lorenze N, Scholten J, Graham G, Sandbrink F, Sico J. Changes in opioid prescribing in veterans with headache during the COVID‐19 pandemic: A regression discontinuity in time analysis. Headache The Journal Of Head And Face Pain 2023, 63: 1295-1303. PMID: 37596904, DOI: 10.1111/head.14605.Peer-Reviewed Original ResearchMorphine equivalent daily dosesVeterans Health AdministrationNumber of prescriptionsOpioid prescribingOpioid prescriptionsLong-term opioid therapyMME/dayRetrospective cohort studyEquivalent daily dosesCOVID-19 pandemicOpioid therapyPre-pandemic periodCohort studyDaily doseChronic painOutpatient visitsPrevious diagnosisDaily dosesMean ageSubgroup analysisHeadache disordersOpioid accessHealth AdministrationPrescribingCoronavirus diseaseThe Current Status of Medical Student Education on Opioids
Jegede O, Na P, Petrakis I, Muvvala S. The Current Status of Medical Student Education on Opioids. 2023, 121-138. DOI: 10.1093/oxfordhb/9780197618431.013.5.Peer-Reviewed Original ResearchTrends in the Use of Gabapentinoids and Opioids in the Postoperative Period Among Older Adults
Bongiovanni T, Gan S, Finlayson E, Ross J, Harrison J, Boscardin W, Steinman M. Trends in the Use of Gabapentinoids and Opioids in the Postoperative Period Among Older Adults. JAMA Network Open 2023, 6: e2318626. PMID: 37326989, PMCID: PMC10276300, DOI: 10.1001/jamanetworkopen.2023.18626.Peer-Reviewed Original ResearchConceptsPostoperative periodCross-sectional studyGabapentinoid prescribingSurgical proceduresConcomitant prescribingGabapentinoid prescriptionOlder adultsPostoperative prescribingProcedure typeSerial cross-sectional studyPatients 66 yearsUse of gabapentinoidsProportion of patientsTotal study cohortAdverse drug eventsCommon surgical procedureConcurrent prescribingMultimodal painPostoperative opioidsOpioid prescribingOpioid usePain SocietyStudy cohortMean ageDrug eventsReal-World Observational Evaluation of Common Interventions to Reduce Emergency Department Prescribing of Opioid Medications
Sangal R, Rothenberg C, Hawk K, D'Onofrio G, Hsiao A, Solad Y, Venkatesh A. Real-World Observational Evaluation of Common Interventions to Reduce Emergency Department Prescribing of Opioid Medications. The Joint Commission Journal On Quality And Patient Safety 2023, 49: 239-246. PMID: 36914528, DOI: 10.1016/j.jcjq.2023.01.013.Peer-Reviewed Original ResearchConceptsOpioid prescribingED visitsElectronic health recordsOpioid prescriptionsEmergency department opioid prescriptionsAnalgesia prescriptionOpioid stewardshipOpioid medicationsSecondary outcomesPrimary outcomePreintervention periodInterruptive alertsCommon interventionPrescribingAlert fatigueElectronic prescribingPrevious interventionsHospital systemObservational evaluationHealth recordsVisitsStewardship policiesInterventionOutcomesPrescriptionSafe Opioid Prescribing and Controlled Substance Policies
Tobin D, Barrette E. Safe Opioid Prescribing and Controlled Substance Policies. 2023, 233-254. DOI: 10.1007/978-3-031-40273-9_16.Peer-Reviewed Original ResearchOpioid prescribingPrimary care physiciansResident continuity clinicProperties of opioidsContinuity clinicCare physiciansRisk of overdoseClinical directorsOpioidIndividual patientsPotential harmAdverse effectsPrescribingPatientsClinicPotential benefitsRegulatory landscapeRiskPotential riskAnalgesicPhysicians
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