2025
Mapping the way to successful euploid frozen embryo transfer: a prospective pilot study of uterine elastography
Margolis C, Garrido N, Roberts L, Reig A, Gill P, Willson S, Genovese H, Barrett F, Zuckerman C, Whitehead C, Bergh P, Seli E, Werner M. Mapping the way to successful euploid frozen embryo transfer: a prospective pilot study of uterine elastography. Human Reproduction 2025, deaf029. PMID: 39999405, DOI: 10.1093/humrep/deaf029.Peer-Reviewed Original ResearchPredictive of clinical pregnancyClinical pregnancyClinical parametersPatient populationShear wave elastographyPosterior myometriumEmbryo transferDay prior to embryo transferElastography parametersEuploid frozen embryo transferLikelihood of clinical pregnancyPredictive valueAlternative patient populationsInfertile patient populationLower uterine segmentPredicting clinical pregnancyFrozen embryo transferLikelihood of conceptionProspective pilot studyMultivariate logistic regression modelReceiver operating characteristic curvePrediction of pregnancyShear wave elastography assessmentsUniversity-affiliated centerAssociated with increased likelihood
2024
Intensive, Real-Time Data Collection of Psychological and Physiological Stress During a 96-Hour Field Training Exercise at a Senior Military College: Feasibility and Acceptability Cohort Study
Pojednic R, Welch A, Thornton M, Garvey M, Grogan T, Roberts W, Ash G. Intensive, Real-Time Data Collection of Psychological and Physiological Stress During a 96-Hour Field Training Exercise at a Senior Military College: Feasibility and Acceptability Cohort Study. JMIR Formative Research 2024, 8: e60925. PMID: 39422988, PMCID: PMC11530722, DOI: 10.2196/60925.Peer-Reviewed Original ResearchConceptsField training exercisePhysical fitnessArmy Reserve Officers' Training Corps cadetsDiagnosis of mental health disordersTraining exercisesPsychological resiliencePoor physical fitnessReserve Officer Training Corps cadetsSelf-reported injuriesMental health disordersField-based trainingData collectionDaily wear timeMilitary field training exercisePhysical readinessTesting adherenceParticipant acceptabilityWear timeHealth disordersMilitary readinessAcceptability surveyOccupational stressorsCohort studyProspective pilot studyEconomic burden
2023
The effect of endoscopic gastric plication on portosystemic pressure gradient in patients with nonalcoholic fatty liver disease and compensated advanced chronic liver disease
Jirapinyo P, Thompson C, Garcia-Tsao G, Zucker S, Ryou M. The effect of endoscopic gastric plication on portosystemic pressure gradient in patients with nonalcoholic fatty liver disease and compensated advanced chronic liver disease. Endoscopy 2023, 56: 56-62. PMID: 37532114, DOI: 10.1055/a-2146-8857.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseEndoscopic gastric plicationAdvanced chronic liver diseaseFatty liver diseasePortosystemic pressure gradientChronic liver diseaseLiver diseaseTotal weight lossGastric plicationNoninvasive testsBaseline median body-mass indexMedian body mass indexPercent total weight lossWeight lossProportion of patientsProspective pilot studyBody mass indexLiver stiffness measurementWeight loss proceduresGoal of therapyHepatic decompensationSecondary outcomesPrimary outcomeMass indexPatients
2022
Nurse Practitioner–Led Integrated Rapid Access to HIV Prevention for People Who Inject Drugs (iRaPID): Protocol for a Pilot Randomized Controlled Trial
Khati A, Altice FL, Vlahov D, Eger WH, Lee J, Bohonnon T, Wickersham JA, Maviglia F, Copenhaver N, Shrestha R. Nurse Practitioner–Led Integrated Rapid Access to HIV Prevention for People Who Inject Drugs (iRaPID): Protocol for a Pilot Randomized Controlled Trial. JMIR Research Protocols 2022, 11: e42585. PMID: 36222826, PMCID: PMC9597427, DOI: 10.2196/42585.Peer-Reviewed Original ResearchINTERNATIONAL REGISTERED REPORT IDENTIFIERSame-day PrEPHIV prevention programsPreliminary efficacyTrial designReal-world settingPrevention programsPre-exposure prophylaxis uptakePilot studyProspective pilot studySignificant public health concernOpioid use disorderHIV prevention strategiesHepatitis C virusOutbreak of HIVEvidence-based preventionPublic health concernInstitutional review boardMOUD initiationControlled TrialsPilot RCTC virusOpioid epidemicHIV preventionNurse practitioners
2021
Peri‐transfusion quality‐of‐life assessment for patients with myelodysplastic syndromes
Abel GA, Klepin HD, Magnavita ES, Jaung T, Lu W, Shallis RM, Hantel A, Bahl NE, Dellinger‐Johnson R, Winer ES, Zeidan AM. Peri‐transfusion quality‐of‐life assessment for patients with myelodysplastic syndromes. Transfusion 2021, 61: 2830-2836. PMID: 34251040, DOI: 10.1111/trf.16584.Peer-Reviewed Original ResearchConceptsRed cell transfusionCell transfusionMyelodysplastic syndromeFollow-up questionnaireTransfusion decisionsQoL assessmentProportion of patientsProspective pilot studyQoL 1Repeat transfusionHemoglobin levelsPatients' qualityScore 7TransfusionPatientsStudy designQoLPilot studySignificant increaseSyndromeLife assessmentSignificant changesDaysQuestionnaireAssessment
2017
(P040) A Prospective Pilot Study of PSA Levels During Post-Operative Prostate-Bed Only Salvage Radiotherapy as A Predictor of Treatment Response
Yang D, Dosoretz A, Yu J. (P040) A Prospective Pilot Study of PSA Levels During Post-Operative Prostate-Bed Only Salvage Radiotherapy as A Predictor of Treatment Response. International Journal Of Radiation Oncology • Biology • Physics 2017, 98: e26. DOI: 10.1016/j.ijrobp.2017.02.135.Peer-Reviewed Original ResearchPredictors of treatment responseProspective pilot studySalvage radiotherapyPSA levelsTreatment responseRadiotherapy
2016
Prospective Study Evaluating Na18F PET/CT in Predicting Clinical Outcomes and Survival in Advanced Prostate Cancer
Apolo AB, Lindenberg L, Shih JH, Mena E, Kim JW, Park JC, Alikhani A, McKinney YY, Weaver J, Turkbey B, Parnes HL, Wood LV, Madan RA, Gulley JL, Dahut WL, Kurdziel KA, Choyke PL. Prospective Study Evaluating Na18F PET/CT in Predicting Clinical Outcomes and Survival in Advanced Prostate Cancer. Journal Of Nuclear Medicine 2016, 57: 886-892. PMID: 26795292, PMCID: PMC6599519, DOI: 10.2967/jnumed.115.166512.Peer-Reviewed Original ResearchConceptsPET/CTAdvanced prostate cancerOverall survivalClinical impressionBone metastasesNumber of lesionsClinical outcomesProstate cancerMalignant lesionsMethylene diphosphonate bone scanProstate-specific antigen (PSA) changesPercentage changeMore bone metastasesDiphosphonate bone scanHigh-risk patientsProspective pilot studyPredicting Clinical OutcomesProstate cancer patientsMaximal percentage changeBone scanAntigen changesCancer patientsPositive lesionsBone diseaseMore lesions
2015
Prospective Pilot Study of a Single Daily Dosage of Trientine for the Treatment of Wilson Disease
Ala A, Aliu E, Schilsky ML. Prospective Pilot Study of a Single Daily Dosage of Trientine for the Treatment of Wilson Disease. Digestive Diseases And Sciences 2015, 60: 1433-1439. PMID: 25605552, PMCID: PMC4427615, DOI: 10.1007/s10620-014-3495-6.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdultAgedChelating AgentsDrug Administration ScheduleFemaleHepatolenticular DegenerationHumansMaleMedication AdherenceMiddle AgedPatient DropoutsPatient SatisfactionPilot ProjectsProspective StudiesSurveys and QuestionnairesTime FactorsTreatment OutcomeTrientineYoung AdultConceptsSingle daily doseWilson's diseaseDaily doseDaily treatment regimenStable Wilson's diseaseProspective pilot studyLiver synthetic functionSingle daily dosageEnd of treatmentResultsAll patientsMaintenance therapyTreatment regimenDaily dosageLifelong therapyLarge trialsZinc excretionUrine copperTreatment stoppageSide effectsTreatment efficacyTrientineTherapyPatientsPilot studyDisease
2012
The Use of Molecular Breast Imaging to Assess Response in Women Undergoing Neoadjuvant Therapy for Breast Cancer
Wahner-Roedler DL, Boughey JC, Hruska CB, Chen B, Rhodes DJ, Tortorelli CL, Maxwell RW, S. S, O'Connor MK. The Use of Molecular Breast Imaging to Assess Response in Women Undergoing Neoadjuvant Therapy for Breast Cancer. Clinical Nuclear Medicine 2012, 37: 344-350. PMID: 22391702, PMCID: PMC3296091, DOI: 10.1097/rlu.0b013e31824437b3.Peer-Reviewed Original ResearchConceptsMolecular breast imagingNeoadjuvant therapyTumor sizeBreast cancerResidual tumor sizeProspective pilot studyInvasive breast cancerBreast cancer treatmentTumor-specific radiopharmaceuticalsPathologic extentResidual diseasePretreatment valuesTumor responseTumor extentPosttreatment valuesIntravenous injectionPathologic measurementsRadiotracer uptakePredictive valueMolecular breastPatientsCancerCancer treatmentPilot studyInterest analysis
2008
Practice Patterns in Choice of Left Double-Lumen Tube Size for Thoracic Surgery
Amar D, Desiderio DP, Heerdt PM, Kolker AC, Zhang H, Thaler HT. Practice Patterns in Choice of Left Double-Lumen Tube Size for Thoracic Surgery. Anesthesia & Analgesia 2008, 106: 379-383. PMID: 18227288, DOI: 10.1213/ane.0b013e3181602e41.Peer-Reviewed Original ResearchConceptsDouble-lumen tubeFr double lumen tubeLung isolationDLT repositioningThoracic surgeryDouble-lumen tube sizeSized double-lumen tubePilot studyIntraoperative outcome measuresLeft mainstem bronchusProspective pilot studyIntraoperative hypoxemiaAirway traumaTransient hypoxemiaFiberoptic bronchoscopyMainstem bronchusIntraoperative outcomesSimilar incidenceBronchial cuffDLT sizePractice patternsOutcome measuresSurgeryHypoxemiaPatients
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